|
2
|
| 1 |
NRP1
|
|
decreases_activity of
|
apoptotic process
|
|
|
19176370
|
Cancer
Amyotrophic lateral sclerosis
|
|
4
|
| 3 |
PLXNA1
|
|
decreases_activity of
|
apoptotic process
|
if levels of Sema6D and Nrp1 are decreased.
|
|
19176370
|
Cancer
Amyotrophic lateral sclerosis
|
|
6
|
| 10 |
KDR
|
|
decreases_activity of
|
apoptotic process
|
|
|
19176370
|
Cancer
Amyotrophic lateral sclerosis
|
|
32
|
| 78 |
SEMA3A
|
|
increases_activity of
|
apoptotic process
|
|
|
18056484
|
Amyotrophic lateral sclerosis
|
|
33
|
| 81 |
FAS
|
|
increases_activity of
|
apoptotic process
|
|
|
18056484
|
Amyotrophic lateral sclerosis
|
|
35
|
| 84 |
FAS
|
|
increases_activity of
|
apoptotic process
|
|
| 85 |
DAXX
|
|
increases_activity of
|
apoptotic process
|
|
|
9215629
|
Amyotrophic lateral sclerosis
|
|
43
|
| 109 |
Doxycycline
|
|
decreases_activity of
|
apoptotic process
|
|
| 117 |
IFNG
|
|
increases_activity of
|
apoptotic process
|
|
|
16551748
|
Diabetes mellitus, type I
|
|
100
|
| 332 |
GSK3B
|
|
increases_activity of
|
apoptotic process
|
if catalytically active GSK3B is overexpressed
|
|
9685326
|
Alzheimer disease
|
|
122
|
| 911 |
GSK3B
|
|
increases_activity of
|
apoptotic process
|
|
|
11527574
|
Alzheimer disease
|
|
205
|
| 817 |
TNF
|
|
decreases_activity of
|
apoptotic process
|
|
| 818 |
LTA
|
|
decreases_activity of
|
apoptotic process
|
|
| 819 |
Glucose
|
|
decreases_activity of
|
apoptotic process
|
|
|
7507336
|
Amyotrophic lateral sclerosis
|
|
297
|
| 1190 |
ANG
|
|
decreases_activity of
|
apoptotic process
|
hypoxia induced
|
| 1194 |
ANG-p.K40I
|
NOT |
decreases_activity of
|
apoptotic process
|
hypoxia induced
|
| 1195 |
ANG-p.R31K
|
NOT |
decreases_activity of
|
apoptotic process
|
hypoxia induced
|
|
19444281
|
Amyotrophic lateral sclerosis
|
|
419
|
| 1853 |
GPAM
|
|
affects_activity of
|
apoptotic process
|
in liver
|
|
17258706
|
Diabetes mellitus, type II
Insulin resistance
|
|
559
|
| 2994 |
STK11
|
|
affects_activity of
|
apoptotic process
|
|
| 2997 |
STK11
|
|
decreases_activity of
|
apoptotic process
|
induced by elevated AMP
|
|
14985505
|
Diabetes mellitus, type II
Peutz-Jeghers syndrome
Cancer
Insulin resistance
|
|
607
|
| 3209 |
SEMA3A
|
|
increases_activity of
|
apoptotic process
|
|
|
17099709
|
Amyotrophic lateral sclerosis
|
|
623
|
| 3381 |
GPAM
|
|
affects_activity of
|
apoptotic process
|
in T-lymphocyte
|
|
18971390
|
Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
|
|
683
|
| 3778 |
Dantrolene
|
|
decreases_activity of
|
apoptotic process
|
in PC12/PS2mt cells; treated with L-glutamate and amyloid beta peptide (25-35)
|
|
16394273
|
Alzheimer disease
|
|
796
|
| 4588 |
NCK1
|
NOT |
affects_activity of
|
apoptotic process
|
|
|
16835242
|
Amyotrophic lateral sclerosis
|
|
809
|
| 4674 |
PDIA2
|
|
decreases_activity of
|
apoptotic process
|
|
|
16724068
|
Alzheimer disease
Parkinson disease
|
|
835
|
| 4981 |
ERN1
|
NOT |
affects_activity of
|
apoptotic process
|
in IRE1alpha-deficient placenta.
|
|
19805353
|
Neurological
Amyotrophic lateral sclerosis
|
|
843
|
| 5001 |
SERTAD1
|
|
affects_activity of
|
apoptotic process
|
|
|
20237268
|
Alzheimer disease
|
|
908
|
| 5422 |
abnormal mitochondrial physiology
|
|
increases_activity of
|
apoptotic process
|
in astrocytes
|
|
19191039
|
Alzheimer disease
|
|
1,081
|
| 6846 |
PTEN
|
|
increases_activity of
|
apoptotic process
|
|
| 6847 |
AKT1
|
|
decreases_activity of
|
apoptotic process
|
|
|
9778245
|
Neurological
|
|
1,304
|
| 8914 |
BCL2L11
|
|
increases_activity of
|
apoptotic process
|
|
| 8915 |
BMF
|
|
increases_activity of
|
apoptotic process
|
|
| 8916 |
BBC3
|
|
increases_activity of
|
apoptotic process
|
|
| 8917 |
PMAIP1
|
|
increases_activity of
|
apoptotic process
|
|
| 8926 |
CTBP2
|
|
decreases_activity of
|
apoptotic process
|
|
|
19798104
|
Disease-related-protein CtBP
|
|
1,305
|
| 8906 |
BIK
|
|
increases_activity of
|
apoptotic process
|
|
|
19798104
|
Disease-related-protein CtBP
|
|
1,307
|
| 8937 |
CTBP2
|
|
decreases_activity of
|
apoptotic process
|
in a p53-independent way
|
|
16508011
|
Disease-related-protein CtBP
|
|
1,323
|
| 9063 |
CTBP2
|
|
decreases_activity of
|
apoptotic process
|
|
|
14567915
|
Disease-related-protein CtBP
|
|
1,324
|
| 9059 |
HIPK2
|
|
increases_activity of
|
apoptotic process
|
via phosphorylation of p53
|
|
14567915
|
Disease-related-protein CtBP
|
|
1,449
|
| 10189 |
GLRX2
|
|
decreases_activity of
|
apoptotic process
|
in mitochondria of mutant SOD1G93A transfected cell lines; if GRX2 is overexpressed
|
| 10208 |
SOD1-p.G93A
|
|
increases_activity of
|
apoptotic process
|
in mitochondria
|
|
20829229
|
Amyotrophic lateral sclerosis
|
|
1,474
|
| 10391 |
EPO
|
|
decreases_activity of
|
apoptotic process
|
|
|
19100675
|
Amyotrophic lateral sclerosis
|
|
1,475
|
| 10401 |
AMPA
|
|
increases_activity of
|
apoptotic process
|
|
| 10405 |
KDR
|
|
decreases_activity of
|
apoptotic process
|
|
|
20456006
|
Amyotrophic lateral sclerosis
|
CIDeRplus