|
194
|
| 812 |
aging
|
|
decreases_activity of
|
Mitochondrial GPAT
|
in splenic T-lymphocytes
|
| 954 |
aging
|
NOT |
decreases_activity of
|
Microsomal GPAT
|
in splenic T-lymphocytes
|
| 955 |
aging
|
NOT |
decreases_activity of
|
LPAAT
|
in splenic T-lymphocytes
|
|
15708364
|
Diabetes mellitus, type II
Insulin resistance
|
|
232
|
| 957 |
aging
|
|
decreases_activity of
|
Mitochondrial GPAT
|
|
|
12573444
|
Diabetes mellitus, type II
Insulin resistance
|
|
429
|
| 1875 |
aging
|
|
affects_activity of
|
Mitochondrial GPAT
|
|
|
11716470
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
658
|
| 3525 |
aging
|
|
increases_activity of
|
amyloid beta deposits
|
increasing the sensitivity of mitochondria to oligomeric Abeta42 damage
|
| 3527 |
aging
|
|
decreases_activity of
|
mitochondrion
|
|
|
19337449
|
Alzheimer disease
|
|
772
|
| 4356 |
aging
|
|
increases_quantity of
|
Reactive oxygen species
|
in skeletal muscle mitochondria
|
|
17584954
|
Amyotrophic lateral sclerosis
|
|
922
|
| 5590 |
Vaccinium (blueberry plant) supplementation
|
|
decreases_activity of
|
aging
|
|
|
12793519
|
Alzheimer disease
|
|
988
|
| 6151 |
aging
|
|
increases_activity of
|
Alzheimer disease
|
|
|
17380553
|
Alzheimer disease
|
|
990
|
| 6148 |
aging
|
|
increases_activity of
|
Alzheimer disease
|
|
|
17380553
|
Alzheimer disease
|
|
1,107
|
| 150123 |
aging
|
|
increases_activity of
|
abnormal cholesterol level
|
at midlife
|
|
20462385
|
Alzheimer disease
Dementia
|
|
1,209
|
| 8107 |
aging
|
|
decreases_quantity of
|
TARDBP
|
|
| 8111 |
aging
|
|
decreases_quantity of
|
FUS
|
|
| 8112 |
aging
|
NOT |
decreases_quantity of
|
TARDBP
|
in motor neurons
|
| 8113 |
aging
|
NOT |
decreases_quantity of
|
FUS
|
in motor neurons
|
|
20616880
|
Amyotrophic lateral sclerosis
|
|
1,237
|
| 8325 |
aging
|
|
increases_expression of
|
HSPB8
|
in G93A-SOD1 mice
|
|
20570967
|
Amyotrophic lateral sclerosis
|
|
1,239
|
| 8324 |
aging
|
|
decreases_expression of
|
HSPB8
|
in wild-type mice
|
|
20570967
|
Amyotrophic lateral sclerosis
|
|
1,253
|
| 8475 |
cellular response to DNA damage stimulus
|
|
increases_activity of
|
aging
|
|
| 8477 |
aging
|
|
increases_activity of
|
Parkinson disease
|
|
|
19616617
|
Parkinson disease
|
|
1,271
|
| 8689 |
aging
|
NOT |
increases_expression of
|
mir-144
|
in human cortex
|
|
20451302
|
Alzheimer disease
|
|
1,275
|
| 8693 |
aging
|
|
increases_expression of
|
mir-144
|
in the aging cerebellum and cortex
|
|
20451302
|
Alzheimer disease
|
|
1,277
|
| 8696 |
aging
|
|
increases_expression of
|
mir-144
|
|
|
20451302
|
Alzheimer disease
|
|
1,377
|
| 9458 |
aging
|
|
increases_activity of
|
protein oxidation
|
|
| 9459 |
aging
|
|
decreases_activity of
|
response to oxidative stress
|
|
| 9460 |
aging
|
|
increases_activity of
|
Alzheimer disease
|
|
| 9461 |
aging
|
|
increases_activity of
|
response to oxidative stress
|
|
| 9635 |
aging
|
|
increases_activity of
|
abnormal mitochondrial physiology
|
brain aging increases mitochondrial mutations
|
|
20552043
|
Alzheimer disease
|
|
1,455
|
| 10266 |
aging
|
|
increases_expression of
|
IL1B
|
in epididymal adipose tissue
|
| 10267 |
aging
|
|
increases_expression of
|
IL6
|
in epididymal adipose tissue
|
| 10268 |
aging
|
|
increases_expression of
|
TNF
|
in epididymal adipose tissue
|
| 10269 |
aging
|
|
increases_expression of
|
PTGS2
|
in epididymal adipose tissue
|
| 10270 |
aging
|
|
decreases_expression of
|
PPARG
|
in epididymal adipose tissue
|
| 10271 |
aging
|
NOT |
affects_quantity of
|
macrophage
|
in adipose tissue
|
| 10274 |
aging
|
|
increases_quantity of
|
Ceramide
|
in adipose tissue
|
| 10280 |
aging
|
|
increases_activity of
|
inflammatory response
|
in adipose tissue
|
|
17878382
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,501
|
| 10598 |
alpha-Tocopherol
|
|
decreases_activity of
|
aging
|
|
|
20890446
|
Parkinson disease
|
|
1,554
|
| 11098 |
aging
|
|
increases_quantity of
|
HAMP
|
in cerebral cortex, hippocampus and striatum
|
|
19898775
|
Alzheimer disease
|
|
1,582
|
| 11398 |
aging
|
|
increases_quantity of
|
amyloid beta deposits
|
|
|
16551656
|
Alzheimer disease
|
|
1,654
|
| 12159 |
aging
|
|
increases_quantity of
|
KL
|
|
|
12196559
|
Alzheimer disease
|
|
1,867
|
| 14185 |
aging
|
|
increases_quantity of
|
amyloid beta deposits
|
|
| 14186 |
aging
|
|
increases_activity of
|
astroglia
|
|
| 14187 |
aging
|
|
increases_activity of
|
microglia
|
|
|
19091971
|
Alzheimer disease
Tauopathy
|
|
1,884
|
| 14305 |
aging
|
|
decreases_activity of
|
immune system process
|
|
| 14306 |
aging
|
|
affects_activity of
|
cell redox homeostasis
|
|
| 14315 |
aging
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
18692159
|
Alzheimer disease
|
|
1,888
|
| 14331 |
aging
|
|
affects_activity of
|
PPARA
|
|
| 14332 |
aging
|
|
affects_activity of
|
PPARG
|
|
|
18313368
|
Alzheimer disease
|
|
1,953
|
| 15137 |
aging
|
|
decreases_quantity of
|
STAT3-phos
|
in hippocampal neurons in AD mouse model and AD patients
|
|
18813209
|
Alzheimer disease
|
|
1,957
|
| 15180 |
aging
|
|
decreases_activity of
|
metabolic process
|
|
|
19076444
|
Alzheimer disease
|
|
2,040
|
| 16313 |
aging
|
|
increases_activity of
|
osteoporosis
|
|
| 16314 |
aging
|
|
increases_activity of
|
Alzheimer disease
|
|
|
21187587
|
Alzheimer disease
|
|
2,108
|
| 17226 |
aging
|
|
increases_quantity of
|
Tryptophan
|
|
|
10693155
|
Autism
|
|
2,143
|
| 17843 |
aging
|
|
increases_expression of
|
SERPINE1
|
|
|
19604604
|
Alzheimer disease
|
CIDeRplus