Search Results for metfmecha - 166 interactions found in 64 entries.

123Next
Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
155
628 AMPK increases_activity of fatty acid beta-oxidation
10051453 Diabetes mellitus, type II
Insulin resistance
258
1061 SREBF1 increases_expression of FASN in liver; after fasting-refeeding treatment
10585467 Diabetes mellitus, type II
Insulin resistance
318
12340 SREBF1 increases_expression of FASN
9421459 Diabetes mellitus, type II
Insulin resistance
341
1339 Metformin decreases_activity of Fatty liver disease, nonalcoholic in ob/ob mice
10973319 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
459
12751 AMPK decreases_activity of CRTC2
16308421 Diabetes mellitus, type II
Peutz-Jeghers syndrome
Insulin resistance
549
2829 AMPK decreases_activity of gluconeogenesis
2838 AMPK decreases_activity of CRTC2
20028864 Breast cancer
Colorectal cancer
Diabetes mellitus, type II
Obesity
Insulin resistance
Metabolic syndrome
559
2983 AMPK decreases_activity of ACACA via phosphorylation at Ser79 of ACC
12836 AMPK increases_activity of fatty acid beta-oxidation via inhibition of ACC
14985505 Diabetes mellitus, type II
Peutz-Jeghers syndrome
Cancer
Insulin resistance
595
3150 AMPK decreases_activity of gluconeogenesis in liver
19665995 Diabetes mellitus, type II
Insulin resistance
664
3755 AMPK decreases_quantity of Malonyl-CoA in liver; if cellular AMP/ATP ratio increases
3757 Malonyl-CoA decreases_activity of fatty acid beta-oxidation in liver
3761 AMPK increases_activity of fatty acid beta-oxidation in liver; by decreasing malonyl-CoA inhibition
10940327 Diabetes mellitus, type II
Diabetes mellitus, type I
Insulin resistance
Hypothyroidism
732
4097 MLXIPL increases_expression of FASN in response to glucose
16614395 Diabetes mellitus, type II
Insulin resistance
904
5383 SIRT1 decreases_activity of Fatty liver disease, nonalcoholic
18599449 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
918
5576 CRTC2 increases_activity of gluconeogenesis in liver; after short-term fasting
5728 SIRT1 decreases_activity of CRTC2
18849969 Diabetes mellitus, type II
Insulin resistance
1,267
8636 FASN increases_activity of lipid biosynthetic process in white adipose tissue
18522830 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
1,574
62055 AMPK decreases_expression of VCAM1 in umbilical vein endothelial cells
62057 AMPK decreases_expression of ICAM1 in umbilical vein endothelial cells
16636195 Diabetes mellitus, type II
Insulin resistance
2,083
16817 Reactive oxygen species increases_quantity of Advanced glycation end-product
16821 Reactive oxygen species increases_activity of NF-kappaB complex
10783895 Diabetes mellitus, type II
Insulin resistance
2,088
16838 Advanced glycation end-product affects_activity of regulation of vascular permeability
16851 VCAM1 increases_activity of atherosclerotic lesions
16852 Diabetes mellitus, type II increases_quantity of Advanced glycation end-product
10082470 Diabetes mellitus, type II
Insulin resistance
2,135
17604 NOS3 increases_quantity of NO if NOS3 is overexpressed
16179591 Diabetes mellitus, type II
Insulin resistance
2,141
17816 AMPK increases_activity of NOS3
20018878 Diabetes mellitus, type II
Insulin resistance
2,403
21406 Diabetes mellitus, type II increases_activity of gluconeogenesis in liver
1401068 Diabetes mellitus, type II
Insulin resistance
2,451
22686 Diabetes mellitus, type II decreases_expression of GLP1R in pancreas, in pancreatic islets
19386626 Diabetes mellitus, type II
Insulin resistance
2,556
23809 ATM rs11212617 affects_activity of Metformin in Europeans, the effective allele is C
21186350 Diabetes mellitus, type II
Insulin resistance
2,558
23821 ATM affects_activity of Metformin
21186350 Diabetes mellitus, type II
Ataxia-telangiectasia
Insulin resistance
2,710
25309 Diabetes mellitus, type II decreases_activity of glucose import in pancreas, in pancreatic islets
21841783 Diabetes mellitus, type II
Obesity
Insulin resistance
Fatty liver disease, nonalcoholic
2,784
25723 Metformin increases_quantity of Glucagon-like peptide 1 in blood plasma
25734 Metformin increases_expression of GLP1R in pancreas, in pancreatic islets
20972533 Diabetes mellitus, type II
Insulin resistance
2,786
25759 Glucagon-like peptide 1 increases_activity of GLP1R
21673955 Diabetes mellitus, type II
Insulin resistance
2,829
26123 Metformin decreases_activity of Mitochondrial respiratory chain complex I
10617608 Diabetes mellitus, type II
Insulin resistance
2,831
26130 Diabetes mellitus, type II increases_activity of gluconeogenesis in liver
11118008 Diabetes mellitus, type II
Insulin resistance
2,868
26442 Metformin decreases_activity of gluconeogenesis in liver; independent of AMPK catalytic chains and independent of STK11 (LKB1)
20577053 Diabetes mellitus, type II
Insulin resistance
2,977
27114 G6PC increases_activity of gluconeogenesis
20374962 Diabetes mellitus, type II
Insulin resistance
MODY, type VI
3,445
32191 PCK1 increases_activity of gluconeogenesis
22040461 Diabetes mellitus, type II
Insulin resistance
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