|
7,548
|
| 74710 |
TH
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
|
| 74711 |
TH
|
|
decreases_quantity of
|
Tyrosine
|
|
| 74712 |
DDC
|
|
decreases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
|
| 74713 |
DDC
|
|
increases_quantity of
|
Dopamine
|
|
| 74714 |
3,4-Dihydroxy-L-phenylalanine
|
|
increases_quantity of
|
Dopamine
|
|
| 74715 |
Tyrosine
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
|
|
|
Metabolic
|
|
13,665
|
| 128368 |
NF-kappaB complex
|
|
increases_quantity of
|
TNF
|
|
|
23664135
|
Immunological
|
|
13,750
|
| 129224 |
kidney
|
|
increases_quantity of
|
Dopamine
|
|
| 129226 |
Dopamine
|
|
decreases_activity of
|
response to oxidative stress
|
|
| 129404 |
Dopamine
|
|
decreases_activity of
|
renin-angiotensin system
|
|
|
22688335
|
Renal
|
|
13,752
|
| 129228 |
Dopamine
|
|
increases_activity of
|
glomerular filtration
|
in kidney
|
| 129234 |
Dopamine
|
|
decreases_activity of
|
Nephropathy, diabetic
|
|
|
22688335
|
Nephropathy, diabetic
|
|
13,808
|
| 129785 |
CCL2
|
|
increases_activity of
|
inflammatory response
|
|
|
25003613
|
Nephropathy, diabetic
|
|
13,867
|
| 130744 |
3,4-Dihydroxy-L-phenylalanine
|
|
increases_quantity of
|
Dopamine
|
in kidney
|
| 130748 |
DDC
|
|
increases_quantity of
|
Dopamine
|
in kidney
|
| 130750 |
Dopamine
|
|
increases_quantity of
|
3-Methoxytyramine
|
|
| 130751 |
COMT
|
|
increases_quantity of
|
3-Methoxytyramine
|
|
| 130752 |
COMT
|
|
decreases_quantity of
|
Dopamine
|
|
| 130753 |
MAOA
|
|
decreases_quantity of
|
Dopamine
|
|
| 130755 |
MAOA
|
|
increases_quantity of
|
3,4-Dihydroxyphenylacetate
|
|
| 130756 |
Dopamine
|
|
increases_quantity of
|
3,4-Dihydroxyphenylacetate
|
|
| 130771 |
Dopamine
|
|
interacts (colocalizes) with
|
DRD1
|
|
| 130772 |
Dopamine
|
|
interacts (colocalizes) with
|
DRD5
|
|
| 130773 |
Dopamine
|
|
interacts (colocalizes) with
|
DRD2
|
|
| 130775 |
Dopamine
|
|
interacts (colocalizes) with
|
DRD3
|
|
| 130776 |
Dopamine
|
|
interacts (colocalizes) with
|
DRD4
|
|
| 130822 |
Dopamine
|
|
increases_activity of
|
glomerular filtration
|
by inhibiting mesangial contraction
|
| 130824 |
Dopamine
|
|
decreases_activity of
|
kidney inflammation
|
by activation of D1-like and D2-like receptors
|
| 130825 |
Dopamine
|
|
decreases_activity of
|
response to oxidative stress
|
by activation of D1-like and D2-like receptors
|
| 132299 |
DDC
|
|
decreases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in kidney
|
| 132365 |
Dopamine
|
|
increases_activity of
|
increased urine sodium level
|
|
| 132498 |
Dopamine
|
|
increases_activity of
|
polyuria
|
in kidney
|
|
25949933
|
Renal
|
|
13,868
|
| 130827 |
DRD2
|
|
increases_expression of
|
PARK7
|
in kidney
|
| 130828 |
DRD2
|
|
increases_expression of
|
PON2
|
in kidney
|
| 130829 |
DRD2
|
|
increases_expression of
|
HMOX2
|
in kidney
|
| 130830 |
PARK7
|
|
decreases_activity of
|
NADPH oxidase complex
|
in kidney
|
| 130831 |
PON2
|
|
decreases_activity of
|
NADPH oxidase complex
|
in kidney
|
| 130832 |
HMOX2
|
|
decreases_activity of
|
NADPH oxidase complex
|
in kidney
|
| 130833 |
DRD5
|
|
decreases_activity of
|
PLD2
|
in kidney
|
| 130834 |
PLD2
|
|
increases_activity of
|
NADPH oxidase complex
|
in kidney
|
|
25949933
|
Renal
Nephropathy, diabetic
|
|
13,869
|
| 130961 |
SLC9A3
|
|
increases_activity of
|
renal sodium ion absorption
|
in renal proximal tubules
|
| 130963 |
renal sodium ion absorption
|
|
increases_activity of
|
sodium ion homeostasis
|
in renal proximal tubules
|
|
18547994
|
Renal
|
|
13,870
|
| 130856 |
EDNRB
|
|
increases_activity of
|
DRD3
|
in proximal tubules of the kidney
|
|
18547994
|
Renal
|
|
13,873
|
| 132191 |
DRD2
|
|
decreases_activity of
|
Sodium:potassium-exchanging ATPase complex
|
in proximal tubule segment; only in the presence of D1-receptor type
|
| 132192 |
DRD1
|
|
affects_activity of
|
DRD2
|
in proximal tubule segment
|
|
1979719
|
Renal
|
|
13,874
|
| 130928 |
DRD2
|
|
decreases_activity of
|
KDR
|
|
| 132190 |
KDR
|
|
increases_activity of
|
angiogenesis
|
|
|
15371263
|
Gastrointestinal
|
|
13,877
|
| 132366 |
Dopamine
|
|
increases_activity of
|
increased urine sodium level
|
|
|
32259353
|
Renal
|
|
13,880
|
| 131021 |
DRD2
|
|
decreases_activity of
|
NF-kappaB complex
|
in renal proximal tubule cells
|
|
22719934
|
Renal
|
|
13,891
|
| 131278 |
Dopamine
|
|
decreases_activity of
|
renin-angiotensin system
|
in kidney
|
|
21701066
|
Renal
|
|
13,894
|
| 131312 |
Dopamine
|
|
decreases_activity of
|
albuminuria
|
in kidney
|
|
22169008
|
Renal
|
|
13,895
|
| 131325 |
NADPH oxidase complex
|
|
increases_quantity of
|
Reactive oxygen species
|
|
|
19330604
|
Renal
|
|
13,911
|
| 131411 |
DRD5
|
|
decreases_quantity of
|
AGTR1
|
in renal proximal tubular cells
|
|
18172057
|
Renal
|
|
13,914
|
| 131415 |
DRD4
|
|
decreases_quantity of
|
AGTR1
|
in renal proximal tubule cells
|
| 131416 |
DRD4
|
|
increases_quantity of
|
AGTR1
|
in renal proximal tubule cells of spontaneously hypertensive rats
|
|
25368031
|
Renal
|
|
13,915
|
| 131417 |
DRD1
|
|
increases_activity of
|
AGTR2
|
|
| 131418 |
AGTR2
|
|
increases_activity of
|
DRD1
|
if AGTR2 has been stimulated with angiotensin III
|
|
31030607
|
Renal
|
|
13,916
|
| 131423 |
SLC9A3
|
|
increases_activity of
|
renal sodium ion absorption
|
in proximal tubules
|
|
28768665
|
Renal
|
|
13,917
|
| 131453 |
Tyrosine
|
|
increases_activity of
|
TH
|
in proximal tubule epithelial cells
|
| 131454 |
TH
|
|
decreases_quantity of
|
Tyrosine
|
in proximal tubule epithelial cells
|
| 131457 |
TH
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in proximal tubule epithelial cells
|
| 131461 |
Tyrosine
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in proximal tubule epithelial cells
|
| 131462 |
3,4-Dihydroxy-L-phenylalanine
|
|
increases_quantity of
|
Dopamine
|
in proximal tubule epithelial cells
|
| 131471 |
DRD1
|
|
decreases_activity of
|
Sodium:potassium-exchanging ATPase complex
|
in proximal tubule epithelial cells
|
| 131836 |
SLC7A8
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in proximal tubule epithelial cells
|
| 131837 |
SLC7A8
|
|
increases_quantity of
|
Tyrosine
|
in proximal tubule epithelial cells; into in renal epithelial cells
|
|
30808844
|
Renal
|
|
13,923
|
| 131545 |
MAO
|
|
decreases_quantity of
|
Dopamine
|
in urine
|
|
16168010
|
Renal
|
|
13,925
|
| 131548 |
RNLS
|
|
decreases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
|
|
24500688
|
Renal
|
|
13,927
|
| 131573 |
DRD5
|
|
increases_expression of
|
RNLS
|
in renal proximal tubule cells; but not in spontaneously hypertensive rats
|
|
24500688
|
Renal
|
|
13,930
|
| 131580 |
SLC7A5
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in renal proximal tubules
|
| 131581 |
SLC7A8
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in renal proximal tubules
|
| 131582 |
SLC1A5
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in renal proximal tubules
|
| 131583 |
SLC6A19
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in renal proximal tubules
|
| 131584 |
aging
|
|
decreases_quantity of
|
Dopamine
|
in urine
|
| 131585 |
Insulin
|
|
increases_quantity of
|
3,4-Dihydroxy-L-phenylalanine
|
in proximal tubular cells
|
| 131794 |
MAOA
|
|
decreases_quantity of
|
Dopamine
|
in kidney
|
| 131801 |
aging
|
|
decreases_quantity of
|
Dopamine
|
|
| 131802 |
hypertension
|
|
decreases_quantity of
|
Dopamine
|
in urine
|
| 131804 |
Diabetes mellitus, type I
|
|
decreases_quantity of
|
Dopamine
|
in kidney
|
| 131805 |
Diabetes mellitus, type II
|
|
decreases_quantity of
|
Dopamine
|
in kidney
|
| 131806 |
Nephropathy, diabetic
|
|
decreases_quantity of
|
Dopamine
|
in kidney
|
| 131927 |
DRD1
|
|
increases_quantity of
|
AGTR2
|
|
| 131928 |
DRD1
|
|
decreases_activity of
|
AGTR1
|
|
| 132045 |
NPPA
|
|
increases_activity of
|
DRD1
|
in renal proximal tubules
|
| 132060 |
DRD3
|
|
increases_quantity of
|
EDNRB
|
in rat renal proximal tubule cells
|
| 132064 |
EDNRB
|
|
decreases_activity of
|
Sodium:potassium-exchanging ATPase complex
|
in rat renal proximal tubule cells
|
| 132065 |
EDNRB
|
|
increases_activity of
|
DRD3
|
in rat renal proximal tubule cells
|
|
23733636
|
Renal
|
|
13,950
|
| 131871 |
DRD1
|
|
decreases_quantity of
|
NLRP3 inflammasome
|
in renal lysates
|
| 132471 |
Dopamine
|
|
decreases_activity of
|
kidney inflammation
|
|
| 132472 |
NLRP3 inflammasome
|
|
increases_activity of
|
inflammatory response
|
in renal lysates
|
|
32446726
|
Renal
|
|
13,951
|
| 131874 |
DRD1
|
|
increases_quantity of
|
INSR
|
in renal proximal tubule cells
|
| 131875 |
DRD1
|
|
interacts (colocalizes) with
|
SNX5
|
in renal proximal tubule cells
|
| 132489 |
SNX5
|
|
increases_quantity of
|
INSR
|
in renal proximal tubule cells
|
|
25825816
|
Renal
|
|
13,952
|
| 131876 |
DRD3
|
|
decreases_activity of
|
REN
|
in kidney
|
|
9691085
|
Renal
|
|
13,954
|
| 131906 |
DRD5
|
|
decreases_quantity of
|
AGTR1
|
in kidney
|
|
18464932
|
Renal
|
|
13,955
|
| 131912 |
DRD5
|
|
decreases_quantity of
|
AGTR1
|
in renal proximal tubule cells and HEK293 cells; via the ubiquitin/proteasome pathway
|
|
18464932
|
Renal
|
CIDeRplus