|
2,966
|
| 27035 |
PDX1
|
|
affects_expression of
|
PAX4
|
in pancreas, in pancreatic islets
|
|
19855005
|
Diabetes mellitus, type II
Insulin resistance
MODY, type IV
|
|
2,991
|
| 27237 |
PAX4 rs121917718
|
|
increases_activity of
|
MODY, type IX
|
in Thais, the effective allele is T (Trp)
|
| 27238 |
PAX4 IVS7-1G>A
|
|
increases_activity of
|
MODY, type IX
|
in Thais
|
| 53290 |
PAX4
|
|
decreases_expression of
|
INS
|
via promoter repression
|
| 53295 |
PAX4
|
|
decreases_expression of
|
GCG
|
via promoter repression
|
| 53296 |
PAX4 rs121917718
|
|
decreases_activity of
|
PAX4
|
if PAX4 acts as repressor
|
|
17426099
|
Diabetes mellitus, type II
Insulin resistance
Nephropathy, diabetic
MODY, type IX
|
|
2,993
|
| 27242 |
PAX4-c.374-412 del39
|
|
increases_activity of
|
MODY, type IX
|
in Japanese
|
| 27243 |
PAX4-c.374-412 del39
|
|
increases_activity of
|
hyperglycemia
|
after fasting, in Japanese
|
| 27244 |
PAX4-c.374-412 del39
|
|
decreases_activity of
|
PAX4
|
in Japanese
|
| 27245 |
PAX4
|
|
decreases_expression of
|
INS
|
in Japanese
|
| 27246 |
PAX4
|
|
decreases_expression of
|
GCG
|
in Japanese
|
|
21263211
|
Diabetes mellitus, type II
Insulin resistance
MODY, type IX
|
|
2,994
|
| 27251 |
PAX4
|
|
affects_activity of
|
type B pancreatic cell apoptotic process
|
if cytokine-mediated
|
| 27259 |
PAX4
|
|
affects_expression of
|
SLC2A2
|
|
| 27260 |
PAX4
|
|
decreases_activity of
|
type B pancreatic cell apoptotic process
|
|
| 27261 |
PAX4
|
|
decreases_activity of
|
NF-kappaB complex
|
|
| 27263 |
PAX4
|
|
increases_activity of
|
type B pancreatic cell proliferation
|
|
|
21521872
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,001
|
| 27331 |
PAX4
|
|
decreases_expression of
|
GCG
|
|
| 27333 |
PAX4
|
|
decreases_expression of
|
INS
|
|
|
10891400
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,473
|
| 53303 |
PAX4
|
|
decreases_expression of
|
INS
|
|
| 53306 |
PAX4
|
|
decreases_expression of
|
GCG
|
|
|
10567552
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,481
|
| 131878 |
PAX4
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
|
11723072
|
Diabetes mellitus, type II
Insulin resistance
MODY, type IX
|
|
5,490
|
| 131877 |
PAX4
|
|
affects_activity of
|
Diabetes mellitus, ketosis-prone
|
|
|
15509590
|
Diabetes mellitus, type II
Insulin resistance
Diabetes mellitus, ketosis-prone
|
|
13,888
|
| 131160 |
PAX4
|
|
affects_activity of
|
MODY, type IX
|
|
| 131165 |
PAX4
|
|
affects_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
|
|
33292863
|
MODY
|
|
13,963
|
| 131932 |
PAX4-p.R164Q
|
|
increases_activity of
|
MODY, type IX
|
|
|
32801813
|
MODY, type IX
|
|
13,966
|
| 131978 |
PAX4-p.R31L
|
|
increases_activity of
|
MODY, type IX
|
|
|
25041077
|
MODY
|
|
13,967
|
| 131981 |
PAX4
|
|
increases_activity of
|
type B pancreatic cell development
|
|
|
28282933
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,969
|
| 131998 |
PAX4-p.Q250del
|
|
increases_activity of
|
MODY, type IX
|
|
|
25951767
|
MODY, type IX
|
CIDeRplus