|
2,476
|
| 22995 |
GCK
|
|
affects_activity of
|
MODY, type II
|
|
|
8433729
|
MODY, type II
Diabetes mellitus, type II
Insulin resistance
|
|
2,477
|
| 132224 |
GCK
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
|
16936201
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,947
|
| 26876 |
MODY, type II
|
|
increases_activity of
|
negative regulation of glycogen biosynthetic process
|
in liver
|
| 26885 |
MODY, type II
|
|
increases_activity of
|
positive regulation of gluconeogenesis
|
in liver
|
| 26888 |
negative regulation of glycogen biosynthetic process
|
|
increases_activity of
|
hyperglycemia
|
|
| 26889 |
positive regulation of gluconeogenesis
|
|
increases_activity of
|
hyperglycemia
|
|
|
8878425
|
MODY, type II
Diabetes mellitus, type II
Insulin resistance
|
|
3,445
|
| 32190 |
GCK
|
|
affects_activity of
|
glucose metabolic process
|
|
|
22040461
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,783
|
| 54588 |
GCK
|
|
increases_activity of
|
insulin secretion
|
in pancreas, in pancreatic beta cells
|
|
25697093
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,365
|
| 60059 |
GCK
|
|
decreases_quantity of
|
Glucose
|
in pancreatic beta cells
|
| 60060 |
GCK
|
|
increases_quantity of
|
Glucose 6-phosphate
|
in pancreatic beta cells
|
|
25070829
|
Diabetes mellitus, type II
Insulin resistance
|
|
7,723
|
| 132607 |
GCK
|
|
affects_activity of
|
Gestational diabetes mellitus
|
|
|
23029294
|
Gestational diabetes mellitus
|
|
9,061
|
| 94969 |
GCK
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreas
|
| 94972 |
GCK
|
|
increases_activity of
|
glycogen biosynthetic process
|
in liver
|
|
29850377
|
MODY, type II
Hypouricemia, renal, 2
|
|
13,888
|
| 131174 |
GCK
|
|
affects_activity of
|
MODY, type II
|
|
| 131176 |
GCK
|
|
affects_activity of
|
detection of glucose
|
|
|
33292863
|
MODY
|
|
13,933
|
| 131639 |
GCK rs587780345
|
|
increases_activity of
|
MODY, type II
|
|
| 131640 |
GCK-p.L185Q
|
|
increases_activity of
|
MODY, type II
|
|
| 131641 |
GCK-p.A208P
|
|
increases_activity of
|
MODY, type II
|
|
| 131642 |
GCK rs1057521093
|
|
increases_activity of
|
MODY, type II
|
|
| 131643 |
GCK rs193922340
|
|
increases_activity of
|
MODY, type II
|
|
| 131644 |
GCK-p.T326P
|
|
increases_activity of
|
MODY, type II
|
|
| 131645 |
GCK-p.R447Lfs
|
|
increases_activity of
|
MODY, type II
|
|
|
31595705
|
MODY
|
|
13,965
|
| 131936 |
GCK rs762263694
|
|
increases_activity of
|
MODY, type II
|
|
| 131937 |
GCK-p.M37T
|
|
increases_activity of
|
MODY, type II
|
|
| 131938 |
GCK rs267601516
|
|
increases_activity of
|
MODY, type II
|
|
| 131939 |
GCK rs1554335761
|
|
increases_activity of
|
MODY, type II
|
|
| 131940 |
GCK-p.K142X
|
|
increases_activity of
|
MODY, type II
|
|
| 131941 |
GCK-p.L146V
|
|
increases_activity of
|
MODY, type II
|
|
| 131942 |
GCK rs193922297
|
|
increases_activity of
|
MODY, type II
|
|
| 131943 |
GCK-p.A173Qfs
|
|
increases_activity of
|
MODY, type II
|
|
| 131944 |
GCK-p.A173T
|
|
increases_activity of
|
MODY, type II
|
|
| 131945 |
GCK-V181D
|
|
increases_activity of
|
MODY, type II
|
|
| 131946 |
GCK rs1554335421
|
|
increases_activity of
|
MODY, type II
|
|
| 131947 |
GCK-p.C220X
|
|
increases_activity of
|
MODY, type II
|
|
| 131948 |
GCK-p.Y234H
|
|
increases_activity of
|
MODY, type II
|
|
| 131949 |
GCK rs193922326
|
|
increases_activity of
|
MODY, type II
|
|
| 131950 |
GCK-p.C252Y
|
|
increases_activity of
|
MODY, type II
|
|
| 131951 |
GCK-p.W257X
|
|
increases_activity of
|
MODY, type II
|
|
| 131952 |
GCK rs1583596378
|
|
increases_activity of
|
MODY, type II
|
|
| 131953 |
GCK-p.G261A
|
|
increases_activity of
|
MODY, type II
|
|
| 131954 |
GCK-c.864-1G>T
|
|
increases_activity of
|
MODY, type II
|
|
| 131955 |
GCK-p.C371X
|
|
increases_activity of
|
MODY, type II
|
|
| 131956 |
GCK rs1415041911
|
|
increases_activity of
|
MODY, type II
|
|
| 131957 |
GCK rs777870079
|
|
increases_activity of
|
MODY, type II
|
|
| 131958 |
GCK-p.E443K
|
|
increases_activity of
|
MODY, type II
|
|
|
33477506
|
MODY
|
|
13,966
|
| 131971 |
GCK-p.E440X
|
|
increases_activity of
|
MODY, type II
|
|
|
25041077
|
MODY
|
|
14,010
|
| 132305 |
GCK rs80356654
|
|
increases_activity of
|
MODY, type II
|
|
| 132306 |
GCK rs104894008
|
|
increases_activity of
|
MODY, type II
|
|
|
33324081
|
MODY
|
|
14,033
|
| 132593 |
GCK rs4607517
|
|
increases_activity of
|
MODY, type II
|
|
|
33363396
|
MODY
|
|
14,038
|
| 132610 |
GCK
|
|
affects_activity of
|
Diabetes mellitus, permanent neonatal, 1
|
|
|
14578306
|
Diabetes mellitus, permanent neonatal
|
|
14,039
|
| 132612 |
GCK
|
|
affects_activity of
|
Hyperinsulinemic hypoglycemia, familial, 3
|
|
|
9435328
|
Hyperinsulinemic hypoglycemia, familial, 3
|
CIDeRplus