|
2,578
|
| 24269 |
KCNJ11
|
|
is_part_of
|
ATP-sensitive potassium channel complex
|
in pancreas, in pancratic beta cells, in pancreatic alpha cells, in intestinal L-cells, in neurons
|
| 24281 |
Sulfonylurea
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreas, in pancreatic beta cells
|
| 24299 |
KCNJ11
|
|
affects_activity of
|
Hyperinsulinemic hypoglycemia, familial, 2
|
|
| 24313 |
KCNJ11
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
|
21968738
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,605
|
| 62959 |
KCNJ11 rs587783672
|
|
increases_activity of
|
MODY, type XIII
|
|
|
22701567
|
Diabetes mellitus, type II
Insulin resistance
MODY, type XIII
|
|
6,639
|
| 63600 |
KCNJ11 rs80356610
|
|
increases_activity of
|
MODY, type XIII
|
|
|
15784703
|
Diabetes mellitus, type II
Insulin resistance
MODY, type XIII
|
|
6,640
|
| 63601 |
KCNJ11 rs774714794
|
|
increases_activity of
|
MODY, type XIII
|
|
| 63602 |
KCNJ11 rs750778014
|
|
increases_activity of
|
MODY, type XIII
|
|
| 63603 |
KCNJ11-p.S116F117del
|
|
increases_activity of
|
MODY, type XIII
|
|
|
24018988
|
Diabetes mellitus, type II
Insulin resistance
MODY, type XIII
|
|
7,420
|
| 72858 |
ATP-sensitive potassium channel complex
|
|
affects_activity of
|
insulin granule exocytosis
|
|
|
26862218
|
Diabetes mellitus, type II
Insulin resistance
|
|
9,122
|
| 97066 |
Insulin
|
|
increases_activity of
|
ATP-sensitive potassium channel complex
|
in lean rats
|
|
29619754
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
13,888
|
| 131194 |
KCNJ11
|
|
affects_activity of
|
MODY, type XIII
|
|
| 131195 |
KCNJ11
|
|
affects_activity of
|
ATP-sensitive potassium channel complex
|
|
| 131196 |
KCNJ11
|
|
affects_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
|
|
33292863
|
MODY
|
|
13,918
|
| 131455 |
ATP-sensitive potassium channel complex
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
| 131458 |
increased ATP/ADP ratio
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131459 |
increased ATP/ADP ratio
|
|
increases_activity of
|
membrane depolarization
|
in pancreatic beta cells
|
| 131463 |
membrane depolarization
|
|
increases_activity of
|
Voltage-gated calcium channel
|
in pancreatic beta cells
|
| 131464 |
membrane depolarization
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 131465 |
calcium ion import
|
|
increases_activity of
|
increased cytosolic calcium level
|
in pancreatic beta cells
|
| 131466 |
increased cytosolic calcium level
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
| 131467 |
Sulfonylurea
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131468 |
Diazoxide
|
|
increases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131475 |
KCNJ11
|
|
affects_activity of
|
Diabetes mellitus, permanent neonatal, 2
|
|
| 131476 |
KCNJ11
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
| 131477 |
KCNJ11
|
|
affects_activity of
|
Diabetes mellitus, transient neonatal 3
|
|
|
16249427
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,919
|
| 131481 |
KCNJ11
|
|
affects_activity of
|
Diabetes mellitus, permanent neonatal, 2
|
|
| 131482 |
KCNJ11
|
|
affects_activity of
|
MODY, type XIII
|
|
| 131483 |
KCNJ11
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
| 131484 |
KCNJ11
|
|
affects_activity of
|
Hyperinsulinemic hypoglycemia, familial, 2
|
|
| 131488 |
glucose import
|
|
increases_activity of
|
increased ATP/ADP ratio
|
in pancreatic beta cells
|
| 131490 |
ATP
|
|
interacts (colocalizes) with
|
KCNJ11
|
in pancreatic beta cells
|
| 131492 |
glucose import
|
|
increases_quantity of
|
ATP
|
in pancreatic beta cells
|
| 131493 |
ATP
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131495 |
increased ATP/ADP ratio
|
|
increases_activity of
|
membrane depolarization
|
in pancreatic beta cells
|
| 131497 |
membrane depolarization
|
|
increases_activity of
|
Voltage-gated calcium channel
|
in pancreatic beta cells
|
| 131498 |
Voltage-gated calcium channel
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 131499 |
calcium ion import
|
|
increases_activity of
|
increased cytosolic calcium level
|
in pancreatic beta cells
|
| 131500 |
increased cytosolic calcium level
|
|
increases_activity of
|
insulin granule exocytosis
|
in pancreatic beta cells
|
| 131501 |
KCNJ11
|
|
affects_activity of
|
hyperglycemia
|
|
| 131502 |
KCNJ11
|
|
affects_activity of
|
hypoglycemia
|
|
| 131503 |
MODY, type XIII
|
|
increases_activity of
|
hyperglycemia
|
|
| 131506 |
Hyperinsulinemic hypoglycemia, familial, 2
|
|
increases_activity of
|
hypoglycemia
|
|
| 131510 |
Hyperinsulinemic hypoglycemia, familial, 2
|
|
increases_activity of
|
increased circulating insulin level
|
|
|
32935446
|
MODY, type XIII
|
|
13,926
|
| 131550 |
LEP
|
|
increases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131552 |
LEP
|
|
decreases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
|
31151172
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,933
|
| 131671 |
KCNJ11 rs766658650
|
|
increases_activity of
|
MODY, type XIII
|
|
|
31595705
|
MODY
|
CIDeRplus