|
2,458
|
| 131574 |
ABCC8
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
|
15111507
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,578
|
| 24268 |
ABCC8
|
|
is_part_of
|
ATP-sensitive potassium channel complex
|
in pancreas, in pancratic beta cells, in pancreatic alpha cells, in intestinal L-cells, in neurons
|
| 24281 |
Sulfonylurea
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreas, in pancreatic beta cells
|
| 24297 |
ABCC8
|
|
affects_activity of
|
Diabetes mellitus, permanent neonatal, 3
|
|
| 24300 |
ABCC8
|
|
affects_activity of
|
Hyperinsulinemic hypoglycemia, familial, 1
|
|
| 24314 |
ABCC8
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
|
21968738
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,002
|
| 27344 |
ABCC8
|
|
affects_activity of
|
Diabetes mellitus, permanent neonatal, 3
|
|
|
18162506
|
Diabetes mellitus, type II
Diabetes mellitus, permanent neonatal
Insulin resistance
MODY, type X
|
|
7,420
|
| 72858 |
ATP-sensitive potassium channel complex
|
|
affects_activity of
|
insulin granule exocytosis
|
|
|
26862218
|
Diabetes mellitus, type II
Insulin resistance
|
|
9,122
|
| 97066 |
Insulin
|
|
increases_activity of
|
ATP-sensitive potassium channel complex
|
in lean rats
|
|
29619754
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
13,888
|
| 131190 |
ABCC8
|
|
affects_activity of
|
MODY, type XII
|
|
|
33292863
|
MODY
|
|
13,918
|
| 131455 |
ATP-sensitive potassium channel complex
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
| 131458 |
increased ATP/ADP ratio
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131459 |
increased ATP/ADP ratio
|
|
increases_activity of
|
membrane depolarization
|
in pancreatic beta cells
|
| 131463 |
membrane depolarization
|
|
increases_activity of
|
Voltage-gated calcium channel
|
in pancreatic beta cells
|
| 131464 |
membrane depolarization
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 131465 |
calcium ion import
|
|
increases_activity of
|
increased cytosolic calcium level
|
in pancreatic beta cells
|
| 131466 |
increased cytosolic calcium level
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
| 131467 |
Sulfonylurea
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131468 |
Diazoxide
|
|
increases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
|
16249427
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,919
|
| 131492 |
glucose import
|
|
increases_quantity of
|
ATP
|
in pancreatic beta cells
|
| 131493 |
ATP
|
|
decreases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131498 |
Voltage-gated calcium channel
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 131500 |
increased cytosolic calcium level
|
|
increases_activity of
|
insulin granule exocytosis
|
in pancreatic beta cells
|
| 131511 |
Hyperinsulinemic hypoglycemia, familial, 1
|
|
increases_activity of
|
hypoglycemia
|
|
| 131512 |
Hyperinsulinemic hypoglycemia, familial, 1
|
|
increases_activity of
|
increased circulating insulin level
|
|
|
32935446
|
MODY, type XIII
|
|
13,926
|
| 131550 |
LEP
|
|
increases_activity of
|
ATP-sensitive potassium channel complex
|
in pancreatic beta cells
|
| 131552 |
LEP
|
|
decreases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
|
31151172
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,932
|
| 131631 |
ABCC8
|
|
affects_activity of
|
MODY, type XII
|
|
| 131632 |
ABCC8 rs193922401
|
|
increases_activity of
|
MODY, type XII
|
|
| 131633 |
ABCC8 rs1274656446
|
|
increases_activity of
|
MODY, type XII
|
|
| 131634 |
ABCC8 rs761757944
|
|
increases_activity of
|
MODY, type XII
|
|
| 131635 |
ABCC8-p.N1245D
|
|
increases_activity of
|
MODY, type XII
|
|
|
21989597
|
MODY, type XII
|
|
13,933
|
| 131663 |
ABCC8-p.S53C
|
|
increases_activity of
|
MODY, type XII
|
|
| 131664 |
ABCC8 rs938611347
|
|
increases_activity of
|
MODY, type XII
|
|
| 131665 |
ABCC8-p.V563D
|
|
increases_activity of
|
MODY, type XII
|
|
| 131666 |
ABCC8 rs149400972
|
|
increases_activity of
|
MODY, type XII
|
|
| 131667 |
ABCC8 rs777986828
|
|
increases_activity of
|
MODY, type XII
|
|
| 131668 |
ABCC8 rs779736828
|
|
increases_activity of
|
MODY, type XII
|
|
| 131669 |
ABCC8 rs775087568
|
|
increases_activity of
|
MODY, type XII
|
|
| 131670 |
ABCC8 rs1262517518
|
|
increases_activity of
|
MODY, type XII
|
|
|
31595705
|
MODY
|
|
13,934
|
| 131674 |
ABCC8
|
|
affects_activity of
|
Hypoglycemia, leucine-induced
|
|
|
15356046
|
Hypoglycemia, leucine-induced
|
|
13,935
|
| 131675 |
ABCC8
|
|
affects_activity of
|
Diabetes mellitus, permanent neonatal, 3
|
|
| 131676 |
ABCC8
|
|
affects_activity of
|
Diabetes mellitus, transient neonatal, 2
|
|
|
16885549
|
Diabetes mellitus, permanent neonatal, 3
Diabetes mellitus, transient neonatal, 2
|
|
13,936
|
| 131684 |
ABCC8 rs769989185
|
|
increases_activity of
|
MODY, type XII
|
|
|
33013711
|
MODY, type XII
|
|
13,965
|
| 131968 |
ABCC8 rs72559717
|
|
increases_activity of
|
MODY, type XII
|
|
|
33477506
|
MODY
|
CIDeRplus