CIDeRplusGeneral Information:
| Id: | 5,454 (click here to show other Interactions for entry) |
| Diseases: |
Metabolic
N-acetylglutamate synthase deficiency - [OMIM] |
| Homo sapiens | |
| review | |
| Reference: | Haberle J(2011) Role of carglumic acid in the treatment of acute hyperammonemia due to N-acetylglutamate synthase deficiency Ther Clin Risk Manag 7: 327-332 [PMID: 21941437] |
Interaction Information:
| Comment | N-acetylglutamate synthase (NAGS) is localized in mitochondrion. NAGS catalyzes the conversion of glutamate and acetyl Co-enzyme A to N-acetylglutamate, which serves as allosteric activator of the first enzyme of the urea cycle, carbamoylphosphate synthetase 1. (cited information) |
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Formal Description Interaction-ID: 53225 |
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| Drugbank entries | Show/Hide entries for NAGS |