General Information:

Id: 11,656 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Mammalia
review
Reference: Cortada E et al.Trafficking and Function of the Voltage-Gated Sodium Channel beta2 Subunit [PMID: 31614896]

Interaction Information:

Comment Within the context of cardiac function, an important result in this regard is the recent finding showing that beta1, by mediating cell-cell adhesion, contributes to spreading of the AP along ventricular cardiomyocytes. Beta1 facilitates coupling of adjacent cells for ion exchange, being located within clefts of the perinexus, i.e., the narrow stretch of membranes closely apposed and adjacent to the gap junctions.
Formal Description
Interaction-ID: 115986

gene/protein

SCN1B

affects_activity of

process

action potential

Drugbank entries Show/Hide entries for SCN1B