Field	Query
							(e.g. PSEN1, beta-amyloid formation, Resveratrol)

	Field	Term

Alzheimer disease

List all interactions

Statistics

Interactions	19586	Proteins/Genes	2701	Chemical compounds/drugs	873
Biological Process(GO)	1244	Phenotype	1384

Proteins/Genes

APOE (isoform E4)	1289
Amyloid beta peptide	539
APP	354
Amyloid beta peptide (42)	294
MAPT	236
APOE	228
APOE (isoform E3)	198
BACE1	190
GSK3B	182
APP (intracellular domain AICD)	158
more...

Biological Process(GO)

aging	400
response to oxidative stress	168
inflammatory response	132
neuron death	76
autophagy	71
apoptotic process	68
amyloid-beta clearance	63
alternative mRNA splicing, via spliceosome	60
menopause transition	58
microglial cell activation	57
more...

Chemical compounds/drugs

Reactive oxygen species	121
Cholesterol	114
Estradiol	110
Melatonin	107
Testosterone	69
N-Acylsphingosine	63
Glucose	55
Estrogen	53
Sphingomyelin	52
ATP	51
more...

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