| 31686 |
APP (CTF-C99)
|
|
increases_quantity of
|
APP (intracellular domain AICD)
|
AICD is a free fragment
|
| 31689 |
IDE
|
|
decreases_activity of
|
APP (intracellular domain AICD)
|
|
| 31694 |
IDE
|
|
decreases_quantity of
|
APP (intracellular domain AICD)
|
by degradation of AICD
|
| 31702 |
APBA1
|
|
decreases_activity of
|
APP (intracellular domain AICD)
|
(AICD-induced transactivation)
|
| 31703 |
APBA2
|
|
decreases_activity of
|
APP (intracellular domain AICD)
|
(AICD-induced transactivation)
|
| 31704 |
APBA3
|
NOT |
affects_activity of
|
APP (intracellular domain AICD)
|
(AICD-induced transactivation)
|
| 31842 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
CD82
|
via promoter-binding
|
| 31844 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
GSK3B
|
|
| 31845 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
APP
|
|
| 31846 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
BACE1
|
|
| 31847 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
KAT5
|
|
| 31851 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
MME
|
via promoter-binding; depending on cell type
|
| 31869 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
PTCH1
|
via promoter-binding
|
| 31870 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
TP53
|
via promoter-binding
|
| 31871 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
TAGLN
|
|
| 31872 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
IGFBP3
|
|
| 31873 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
S100A9
|
|
| 31874 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
AQP1
|
|
| 31875 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
SLC17A6
|
|
| 31876 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
CCNB1
|
|
| 31877 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
CCND1
|
|
| 31878 |
APP (intracellular domain AICD)
|
|
decreases_expression of
|
EGFR
|
via promoter-binding
|
| 31879 |
APP (intracellular domain AICD)
|
|
decreases_expression of
|
LRP1
|
via promoter-binding
|
| 31880 |
APP (intracellular domain AICD)
|
|
decreases_expression of
|
CLU
|
|
| 31881 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
DDIT3
|
via promoter-binding
|
| 31883 |
APP (intracellular domain AICD)
|
|
increases_expression of
|
ACTA2
|
|
| 52848 |
PSEN1
|
|
affects_quantity of
|
APP (intracellular domain AICD)
|
|
| 52849 |
PSEN2
|
|
affects_quantity of
|
APP (intracellular domain AICD)
|
|
| 52853 |
APP (CTF-C99)
|
|
increases_quantity of
|
APP (intracellular domain AICD)
|
both C83 and C99 behave as potential precursors of AICD
|
| 52854 |
APP (CTF-C83)
|
|
increases_quantity of
|
APP (intracellular domain AICD)
|
|
| 52856 |
Alzheimer disease
|
|
increases_quantity of
|
APP (intracellular domain AICD)
|
in sporadic AD-affected brains
|
| 52861 |
GRB2
|
|
interacts (colocalizes) with
|
APP (intracellular domain AICD)
|
|
| 52862 |
ABL1
|
|
interacts (colocalizes) with
|
APP (intracellular domain AICD)
|
|
| 52863 |
NUMB
|
|
interacts (colocalizes) with
|
APP (intracellular domain AICD)
|
|
| 52864 |
DAB1
|
|
interacts (colocalizes) with
|
APP (intracellular domain AICD)
|
|
| 52865 |
SHC1
|
|
interacts (colocalizes) with
|
APP (intracellular domain AICD)
|
|
| 52866 |
SHC2
|
|
interacts (colocalizes) with
|
APP (intracellular domain AICD)
|
|
| 52867 |
APP (intracellular domain AICD)
|
|
is localized in
|
nucleus
|
|
| 52868 |
APP (intracellular domain AICD)
|
|
interacts (colocalizes) with
|
APBB1
|
|
| 52869 |
APP (intracellular domain AICD)
|
|
interacts (colocalizes) with
|
NOTCH (intracellular domain NICD)
|
|
| 52870 |
APP (intracellular domain AICD)
|
|
affects_activity of
|
calcium ion homeostasis
|
|
| 52871 |
APP (intracellular domain AICD)
|
|
increases_activity of
|
cell death
|
in Jurkat cells; FADD (Fas domain associated protein)-induced cell death;
|
| 52872 |
APP (intracellular domain AICD)
|
|
interacts (colocalizes) with
|
TP53 (promoter)
|
|
| 67185 |
APP (intracellular domain AICD)
|
|
increases_quantity of
|
APP (cytotoxic fragment C31)
|
|
AlzNet-DB