Search Results for "menopause transition" - 58 interactions found in 4 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
12,066
118441 menopause transition increases_activity of decreased circulating estrogen level
118518 hormone replacement therapy decreases_activity of menopause transition when started during perimenopause
130634 menopause transition decreases_activity of Mitochondrial respiratory chain complex IV in a cohort of 43, 40‚Äď60 year-old clinically and cognitively normal women at different endocrine transition stages including premenopause, perimenopause and postmenopause; compared to premenopause, correlated with a decline of cerebral glucose metabolism in AD-vulnerable regions
130649 menopause transition decreases_activity of decreased brain glucose metabolic process in a cohort of 43, 40‚Äď60 year-old clinically and cognitively normal women at different endocrine transition stages including premenopause, perimenopause and postmenopause; compared to premenopause, correlated with a reduction in mitochondrial COX activity
130651 menopause transition increases_activity of Alzheimer disease in aging females
130652 menopause transition decreases_activity of response to estrogen in female animal studies; faltered estrogenic regulation of cerebral glucose metabolism
130653 menopause transition increases_activity of decreased brain glucose metabolic process in female animal studies; faltered estrogenic regulation of cerebral glucose metabolism
29755342
13,668
128426 menopause transition increases_activity of abnormal mitochondrial physiology in female brain; depending on stage-specific shift of chronological and endocrinological transition
128427 menopause transition decreases_activity of glucose metabolic process in female brain; depending on stage-specific shift of chronological and endocrinological transition
132465 aging increases_activity of menopause transition in aging female brain
32444841
14,021
132448 menopause transition increases_activity of reproductive senescence
132505 menopause transition increases_activity of decreased ovarian follicle number
132507 menopause transition decreases_expression of SLC2A3 in the hippocampus of 9-10 m irregular cyclers; compared to 9‚Äď10 month regular cyclers
132510 menopause transition decreases_expression of HSPD1 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132511 menopause transition increases_activity of irregular cycling
132512 menopause transition increases_activity of abnormal fertility/fecundity
132513 menopause transition increases_activity of irregular steroid hormone fluctuation
132514 menopause transition increases_activity of insensitivity to estrogen
132518 menopause transition decreases_expression of PDHA1 in the hippocampus of 9-10 m irregular cyclers; compared to 9-10 m regular cyclers
132519 menopause transition decreases_expression of ATPAF2 in the hippocampus of 9-10 m irregular cyclers; compared to 9-10 m regular cyclers
132524 menopause transition increases_expression of CPT2 when the rats transitioned from irregular cycling to acyclic
132525 menopause transition increases_expression of ESRRA when the rats transitioned from irregular cycling to acyclic
132526 menopause transition NOT affects_expression of genes involved in glycolysis when the rats transitioned from irregular cycling to acyclic, transient response, lost with further chronological aging to 16 months
132530 menopause transition decreases_expression of BNIP1 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132531 menopause transition increases_expression of NFE2L2 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in redox-sensitive transcription
132532 menopause transition decreases_expression of GLRX2 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132533 menopause transition decreases_expression of PRDX3 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132534 menopause transition decreases_expression of GAD1 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132535 menopause transition decreases_expression of GAD2 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132538 menopause transition decreases_expression of CXCR4 in 9‚Äď10 month regular cyclers; a neuronal survival gene, compared to 6-month cyclers
132578 menopause transition increases_expression of HADH in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in lipid metabolism
132579 menopause transition increases_expression of PLCG2 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in lipid metabolism
132580 menopause transition increases_expression of PLCD1 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in lipid metabolism
132581 menopause transition increases_expression of APOA1 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132582 menopause transition increases_expression of ABCA7 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers
132583 menopause transition increases_expression of C4A in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in inflammation
132584 menopause transition increases_expression of APEH in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in amyloid processing
132585 menopause transition increases_expression of CASP8 in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in apoptosis
132586 menopause transition increases_expression of CLU in 9‚Äď10 month regular cyclers; compared to 6-month cyclers, involved in apoptosis
132622 menopause transition increases_quantity of Estradiol in serum of the 9‚Äď10 month regular and irregular cyclers ; serum E2 was not correlated with cortex E2 at the same endocrine stage
132623 menopause transition increases_quantity of Progesterone in serum of the 9‚Äď10 month irregular cyclers; serum P4 levels were correlated with cortical levels
132625 menopause transition increases_expression of PGR (isoform A) in 9‚Äď10 month irregular cyclers; compared to 6 month regular cyclers
132627 menopause transition decreases_quantity of Estradiol in cortex of 6 month to 9‚Äď10 month rats; serum E2 was not correlated with cortex E2 at the same endocrine stage
132628 menopause transition decreases_quantity of Progesterone in serum of the transition into 9‚Äď10 month acyclic and in the cortex from 6 month regular to 9‚Äď10 month regular and irregular cyclers; serum P4 levels were correlated with cortical levels, remaining low in the 16 month acyclic group
132631 menopause transition decreases_expression of ESR2 in the 9‚Äď10 month irregular cyclers
132634 menopause transition increases_expression of PGR (isoform B) in 9‚Äď10 month irregular cyclers; compared to 6 month regular cyclers
132635 menopause transition NOT affects_expression of PGRMC1 in all compared groups of the Perimenopause Animal Model (PAM)
132636 menopause transition increases_expression of PGR in 9‚Äď10 month irregular cyclers; compared to 6 month regular cyclers, concerning both isoforms A and B
133264 menopause transition increases_expression of PLD1
133272 menopause transition increases_expression of HRH1
133926 menopause transition decreases_expression of PPARG in the 16 month acyclic group; compared to the 9‚Äď10 month acyclic group
133986 menopause transition decreases_expression of PLA2G1B in the 16 month acyclic group; compared to the 9‚Äď10 month acyclic group
25921624
14,463
136490 menopause transition increases_activity of increased decline in estrogen-dependent memory tests in postmenopausal perimenopausal women; compared to males / men
136496 menopause transition increases_activity of increased decline in cerebral metabolic rate of glucose consumption in postmenopausal perimenopausal women; compared to males / men
136505 menopause transition increases_activity of decreased hippocampus volume in postmenopausal women/females; compared to males / men
136509 menopause transition increases_quantity of amyloid beta deposits in both PCC (posterior cingulate cortex) and frontal cortex of postmenopausal women; compared to the PRE (15 premenopausal controls) and male groups
136519 menopause transition increases_quantity of amyloid beta deposits in frontal cortex of perimenopausal women; compared to the premenopausal control group and men
136520 menopause transition increases_quantity of amyloid beta deposits in postmenopausal women; compared to males / men
30540774
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