|
908
|
| 5423 |
Reactive oxygen species
|
|
increases_activity of
|
inflammatory response
|
in astrocytes; if ROS production is Abeta-induced
|
| 5514 |
Resveratrol
|
|
decreases_activity of
|
inflammatory response
|
|
| 5551 |
Curcumin
|
|
decreases_activity of
|
inflammatory response
|
|
|
19191039
|
|
985
|
| 6135 |
Allium sativum (garlic) supplementation
|
|
decreases_activity of
|
inflammatory response
|
|
| 6136 |
S-allyl-cysteine
|
|
decreases_activity of
|
inflammatory response
|
|
| 6137 |
Di-allyl-disulfide
|
|
decreases_activity of
|
inflammatory response
|
|
|
16842945
|
|
1,057
|
| 6606 |
PS cDKO mouse
|
|
increases_activity of
|
inflammatory response
|
in neocortex and hippocampus
|
|
15345711
|
|
1,102
|
| 6995 |
Alzheimer disease
|
|
increases_activity of
|
inflammatory response
|
in PBMCs from AD patients compared to PBMCs in healthy controls
|
|
20462385
|
|
1,107
|
| 7080 |
amyloid beta deposits
|
|
affects_activity of
|
inflammatory response
|
in AD brain
|
| 7094 |
inflammatory response
|
|
increases_activity of
|
microglia
|
concerning local or systemic inflammation
|
| 145268 |
neurofibrillary tangles
|
|
affects_activity of
|
inflammatory response
|
in AD brain
|
|
20462385
|
|
1,111
|
| 7125 |
inflammatory response
|
|
affects_activity of
|
TGFB1
|
in brain
|
|
11329064
|
|
1,112
|
| 7184 |
transgenic hAPP/TGFbeta1 mouse
|
|
increases_activity of
|
inflammatory response
|
in transgenic hAPP/TGF-beta1 mice
|
|
11329064
|
|
1,119
|
| 7180 |
CFH
|
|
decreases_activity of
|
inflammatory response
|
|
|
18801740
|
|
1,154
|
| 8245 |
CD14
|
|
affects_activity of
|
inflammatory response
|
|
| 8246 |
TLR2
|
|
affects_activity of
|
inflammatory response
|
|
|
17905482
|
|
1,169
|
| 7760 |
IL1B
|
|
affects_activity of
|
inflammatory response
|
|
|
15290893
|
|
1,184
|
| 7845 |
microglial cell activation
|
|
increases_activity of
|
inflammatory response
|
within the diseased brain
|
| 7858 |
Amyloid beta peptide (fibrillar)
|
|
increases_activity of
|
inflammatory response
|
|
|
17094809
|
|
1,302
|
| 8898 |
Alzheimer disease
|
|
affects_activity of
|
inflammatory response
|
|
| 8899 |
monocyte-derived dendritic cell
|
|
affects_activity of
|
inflammatory response
|
in AD patients
|
|
20110602
|
|
1,422
|
| 10037 |
inflammatory response
|
|
increases_activity of
|
Cytokine
|
|
|
19021541
|
|
1,554
|
| 11092 |
inflammatory response
|
|
affects_quantity of
|
HAMP
|
|
| 11104 |
inflammatory response
|
|
affects_activity of
|
iron ion homeostasis
|
|
|
19898775
|
|
1,588
|
| 11454 |
innate immune response
|
|
affects_activity of
|
inflammatory response
|
|
| 11455 |
inflammatory response
|
|
increases_quantity of
|
Proinflammatory cytokine
|
|
| 11688 |
response to nitrosative stress
|
|
affects_activity of
|
inflammatory response
|
|
|
20463396
|
|
1,688
|
| 12720 |
inflammatory response
|
|
affects_expression of
|
mir-17
|
|
|
20888417
|
|
1,745
|
| 13118 |
Alzheimer disease
|
|
increases_activity of
|
inflammatory response
|
in postmortem AD brain
|
| 13183 |
Amyloid beta peptide
|
|
increases_activity of
|
inflammatory response
|
|
|
12270682
|
|
1,820
|
| 13675 |
IRAK2
|
|
increases_activity of
|
inflammatory response
|
if IRAK-2 is NF-kappaB-induced upregulated
|
|
20937840
|
|
1,884
|
| 14307 |
immune system process
|
|
affects_activity of
|
inflammatory response
|
|
| 14311 |
cell redox homeostasis
|
|
affects_activity of
|
inflammatory response
|
|
| 14320 |
inflammatory response
|
|
affects_activity of
|
macrophage activation
|
|
|
18692159
|
|
1,888
|
| 14330 |
PPARA
|
|
affects_activity of
|
inflammatory response
|
via close association with increased levels of inflammatory mediators during the aging
|
| 14335 |
PPARG
|
|
decreases_activity of
|
inflammatory response
|
by inhibiting the expression of inflammatory genes, such as cytokines, matrix metalloproteases
|
| 14339 |
PPARA
|
|
decreases_activity of
|
inflammatory response
|
by inhibiting the expression of inflammatory genes, such as cytokines, matrix metalloproteases
|
| 14401 |
inflammatory response
|
|
affects_quantity of
|
PTGS2
|
|
|
18313368
|
|
1,914
|
| 14683 |
Glutathione
|
|
affects_activity of
|
inflammatory response
|
in glia cells; Decreasing intracellular levels of GSH induce a neuroinflammatory response in microglia and astrocytes.
|
| 14850 |
response to oxidative stress
|
|
affects_activity of
|
inflammatory response
|
Oxidative stress induced by inhibition of glutathione (GSH) biosynthesis is correlated with activation of the inflammatory pathways.
|
|
20228251
|
|
2,121
|
| 17382 |
AD11 anti-NGF mouse
|
|
affects_activity of
|
inflammatory response
|
|
| 17396 |
inflammatory response
|
|
affects_activity of
|
Alzheimer disease
|
|
|
19604602
|
|
2,249
|
| 19228 |
Atorvastatin
|
|
decreases_activity of
|
inflammatory response
|
|
|
21536132
|
|
2,278
|
| 19438 |
NSAID
|
|
decreases_activity of
|
inflammatory response
|
|
| 27791 |
Triflusal
|
|
affects_activity of
|
inflammatory response
|
in AD
|
|
21345168
|
|
2,315
|
| 19938 |
Tg2576 mouse
|
|
increases_activity of
|
inflammatory response
|
to lipopolysaccharide
|
| 19949 |
Lipopolysaccharide
|
|
increases_activity of
|
inflammatory response
|
|
| 19951 |
amyloid beta deposits
|
|
increases_activity of
|
inflammatory response
|
in AD brain
|
|
11786245
|
|
2,389
|
| 21273 |
astrocyte
|
|
increases_activity of
|
inflammatory response
|
|
| 21275 |
Minocycline
|
|
decreases_activity of
|
inflammatory response
|
when the astrocytic response was attenuated with minocycline
|
|
21633390
|
|
2,525
|
| 23548 |
Somatostatin
|
|
affects_activity of
|
inflammatory response
|
|
| 23549 |
EDN1
|
|
affects_activity of
|
inflammatory response
|
|
| 23550 |
Bradykinin
|
|
affects_activity of
|
inflammatory response
|
|
|
20937084
|
|
2,576
|
| 24262 |
S100A8
|
|
affects_activity of
|
inflammatory response
|
|
| 24263 |
S100A9
|
|
affects_activity of
|
inflammatory response
|
|
|
19196476
|
|
3,238
|
| 29898 |
Curcumin
|
|
decreases_activity of
|
inflammatory response
|
|
|
15974909
|
|
3,449
|
| 32214 |
inflammatory response
|
|
increases_quantity of
|
CCL2
|
in brain
|
|
22303443
|
AlzNet-DB