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| EXAMPLE | |
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This example is related to the clinical study (Denkert et al, 2006).
In this study a set of sixty-six invasive ovarian carcinomas
and nine borderline tumors of the ovary were analyzed
by gas chromatography/time-of-flight mass spectrometry (GCTOF MS).
After automated mass spectral deconvolution, 291 metabolites were detected,
of which 114 (39.1%) were annotated as known compounds.
By a t test statistics with P < 0.01, 51 metabolites were identified
to be significantly different between borderline tumors and carcinomas.
In the paper 21 significantly different metabolites that are mapped to the global metabolic network
were reported. The KEGG Ids for this compounds are presented below.
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