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General information


80
17616664
Homo sapiens (9606)
disease
Hepatocellular carcinoma

Study information


Patient study phenotype-phenotype
Phenotype 1: patients with HCC (hepatocellular carcinoma) arisen on cirrhotic livers (n=17); Phenotype 2: patients with LC (liver cirrhosis) (n=21);
liver

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7a-1 miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 1.47
2 hsa-let-7a-2 miRNA microarray miRNA downregulation 1.69
3 hsa-let-7a-3 miRNA microarray miRNA downregulation 1.59
4 hsa-let-7b miRNA microarray miRNA downregulation 1.35
5 hsa-let-7c miRNA microarray miRNA downregulation 1.61
6 hsa-let-7d miRNA microarray miRNA downregulation 1.43
7 hsa-let-7e miRNA microarray miRNA downregulation 1.3
8 hsa-let-7f-2 miRNA microarray miRNA downregulation 1.43
9 hsa-let-7g miRNA microarray miRNA downregulation 1.41
10 hsa-mir-122 miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 1.59 CCNG1
11 hsa-mir-124-2 miRNA microarray miRNA downregulation 1.45
12 hsa-mir-130a miRNA microarray miRNA downregulation 2
13 hsa-mir-132 miRNA microarray miRNA downregulation 1.33
14 hsa-mir-136 miRNA microarray miRNA downregulation 1.72
15 hsa-mir-141 miRNA microarray miRNA downregulation 1.35
16 hsa-mir-142 miRNA microarray miRNA downregulation 1.96
17 hsa-mir-143 miRNA microarray miRNA downregulation 1.39
18 hsa-mir-145 miRNA microarray miRNA downregulation 1.87
19 hsa-mir-146a miRNA microarray miRNA downregulation 1.69
20 hsa-mir-150 miRNA microarray miRNA downregulation 2.13
21 hsa-mir-155 miRNA microarray miRNA downregulation 1.75
22 hsa-mir-181a-1 miRNA microarray miRNA downregulation 1.47
23 hsa-mir-181a-2 miRNA microarray miRNA downregulation 1.56
24 hsa-mir-181c miRNA microarray miRNA downregulation 1.49
25 hsa-mir-195 miRNA microarray miRNA downregulation 1.33
26 hsa-mir-199a-1 miRNA microarray miRNA downregulation 2.22
27 hsa-mir-199a-2 miRNA microarray miRNA downregulation 2.33
28 hsa-mir-199b miRNA microarray miRNA downregulation 2.04
29 hsa-mir-200b miRNA microarray miRNA downregulation 1.35 - 1.45
30 hsa-mir-214 miRNA microarray miRNA downregulation 1.69
31 hsa-mir-221 miRNA microarray Northern Blot, quantitative PCR miRNA overexpression 1.49
32 hsa-mir-223 miRNA microarray miRNA downregulation 2.27

Detailed information about selected miRNA


hsa-let-7a-1
miRNA microarray
Northern Blot, quantitative PCR
miRNA downregulation
1.47    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

Comments


General comment: HCC (hepatocellular carcinoma) microarray data for each microRNA were normalized on respective cirrhosis.