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General information


78
18521080
Homo sapiens (9606)
disease
Hepatocellular carcinoma

Study information


Patient study phenotype-control
liver

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-221 quantitative PCR miRNA overexpression CDKN1BCDKN1C

Detailed information about selected miRNA


hsa-mir-221
quantitative PCR
miRNA overexpression
   

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment
CDKN1B down translational repression The results suggest that miR-221, which is upregulated in 71% of HCCs, has an oncogenic function through the inhibition of CDKN1C/p57 and CDKN1B/p27 protein expression.
CDKN1C down translational repression The results suggest that miR-221, which is upregulated in 71% of HCCs, has an oncogenic function through the inhibition of CDKN1C/p57 and CDKN1B/p27 protein expression.

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