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General information


653
19127597
Homo sapiens (9606)
disease
Bladder cancer
Urothelial carcinomas originate from the epithelial cells of the inner lining of the bladder wall. The majority is papillary and confined to the urothelial mucosa (stage Ta) or to the lamina propria (Stage T1), whereas the remaining invades the underlying muscle tissue (T2), perivesical fat (T3) or surrounding organs (T4). Data of this entry refer to T2/T3 tumors.

Study information


Patient study phenotype-phenotype
17
Altogether 7 Ta, 10 T1 and 17 T2/3 tumors were included in the study. Of these, 10 were low-grade (grades G1 and G2) and 24 high-grade (G3) tumors.
urothelium

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-100 miRNA microarray miRNA overexpression 2.17
2 hsa-mir-125b-1 miRNA microarray miRNA overexpression 2.02
3 hsa-mir-199b miRNA microarray miRNA overexpression 1.94
4 hsa-mir-222 miRNA microarray miRNA overexpression 1.8

Detailed information about selected miRNA


hsa-mir-100
miRNA microarray
miRNA overexpression
2.17    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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