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General information

Homo sapiens (9606)
Bladder cancer
Urothelial carcinomas originate from the epithelial cells of the inner lining of the bladder wall. The majority is papillary and confined to the urothelial mucosa (stage Ta) or to the lamina propria (Stage T1), whereas the remaining invades the underlying muscle tissue (T2), perivesical fat (T3) or surrounding organs (T4). Data of this entry refer to T2/T3 tumors.

Study information

Patient study phenotype-phenotype
Altogether 7 Ta, 10 T1 and 17 T2/3 tumors were included in the study. Of these, 10 were low-grade (grades G1 and G2) and 24 high-grade (G3) tumors.

miRNA list

Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-100 miRNA microarray miRNA overexpression 2.17
2 hsa-mir-125b-1 miRNA microarray miRNA overexpression 2.02
3 hsa-mir-199b miRNA microarray miRNA overexpression 1.94
4 hsa-mir-222 miRNA microarray miRNA overexpression 1.8

Detailed information about selected miRNA

miRNA microarray
miRNA overexpression

Genes associated with selected miRNA

target gene regulation mechanism of regulation comment


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