General search

List as:
Entries miRNAs
Search type:
Fuzzy Strict


Specific search

List as:
Entries miRNAs
Search type:
Fuzzy Strict

About phenomir

List all entries
List all diseases
List all miRNAs


© 2009 - Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH) Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany

Data Protection Statement

MIPS Databases and associated information are protected by copyright. This server and its associated data and services are for academic, non-commercial use only. The Helmholtz Zentrum München has no liability for the use of results, data or information which have been provided through this server. Neither the use for commercial purposes, nor the redistribution of MIPS database files to third parties nor the distribution of parts of files or derivative products to any third parties is permitted.

Home > List > Detailed view

General information

Homo sapiens (9606)
Rheumatoid arthritis

Study information

Patient study phenotype-control
Experiments were done in sorted CD3+, CD4+ and CD8+ lymphocytes of patients with active RA (Rheumatoid arthritis) and healthy control subjects.

miRNA list

Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-223 miRNA microarray quantitative PCR miRNA overexpression

Detailed information about selected miRNA

miR-223 is predominantly expressed in CD4+ cells..
miRNA microarray
quantitative PCR
miRNA overexpression

Genes associated with selected miRNA

target gene regulation mechanism of regulation comment


General comment: CD4+ cells have been highlighted previously as key players in RA pathology. It is therefore of interest that this subpopulation seems to be responsible for most of the miR-223 measured within the CD3+ cells of RA patients.