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General information


4
16039986
Homo sapiens (9606)
disease
Glioblastoma multiforme, somatic

Study information


Cell culture study
A-172 cell
This study included 10 glioblastoma cell lines (DBTRG-05MG, U118, U87, A172, LN18, M059J, M059K, LN229, T98G, U138MG). miRNA expression profiles were compared with those of two adult and two fetal normal brain samples.

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-125b-1 miRNA microarray miRNA downregulation 3.23
2 hsa-mir-125b-2 miRNA microarray miRNA downregulation 2.56
3 hsa-mir-128-2 miRNA microarray Northern Blot miRNA downregulation 1.89
4 hsa-mir-181a-2 miRNA microarray Northern Blot miRNA downregulation 2.86
5 hsa-mir-181b-1 miRNA microarray Northern Blot miRNA downregulation 2.94
6 hsa-mir-181c miRNA microarray miRNA downregulation 2.04
7 hsa-mir-191 miRNA microarray miRNA overexpression 1.92
8 hsa-mir-197 miRNA microarray miRNA downregulation 3.03
9 hsa-mir-21 miRNA microarray miRNA overexpression 1.61
10 hsa-mir-220a miRNA microarray miRNA overexpression 1.68
11 hsa-mir-221 miRNA microarray Northern Blot miRNA overexpression 5.34 CDKN1B
12 hsa-mir-222 miRNA microarray miRNA overexpression 2.43 CDKN1B
13 hsa-mir-23a miRNA microarray miRNA overexpression 6.22
14 hsa-mir-23b miRNA microarray miRNA overexpression 3.28
15 hsa-mir-24-1 miRNA microarray miRNA overexpression 1.83
16 hsa-mir-24-2 miRNA microarray miRNA overexpression 1.88

Detailed information about selected miRNA


hsa-mir-125b-1
miRNA microarray
miRNA downregulation
3.23    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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