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General information


498
17108120
Homo sapiens (9606)
response to folate starvation
Expression of miRNAs was analysed in lymphoblast cell line TK-6 cultured in standard medium RPMI 1640 or folate-deficient medium RPMI 1640 for 6 days.

Study information


Bioprocess study
cell culture

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-103-1 miRNA microarray miRNA overexpression 1.62
2 hsa-mir-107 miRNA microarray miRNA overexpression 1.62
3 hsa-mir-125b-1 miRNA microarray miRNA overexpression 2.89
4 hsa-mir-130b miRNA microarray miRNA overexpression 1.8
5 hsa-mir-145 miRNA microarray miRNA overexpression 2.79
6 hsa-mir-146a miRNA microarray miRNA overexpression 2.8
7 hsa-mir-181a-1 miRNA microarray miRNA overexpression 2.29
8 hsa-mir-181b-1 miRNA microarray miRNA overexpression 2.49
9 hsa-mir-182 miRNA microarray miRNA overexpression 2.7
10 hsa-mir-183 miRNA microarray miRNA overexpression 2.35
11 hsa-mir-191 miRNA microarray miRNA overexpression 1.62
12 hsa-mir-198 miRNA microarray miRNA downregulation 1.78
13 hsa-mir-205 miRNA microarray miRNA overexpression 3.62
14 hsa-mir-210 miRNA microarray quantitative PCR miRNA downregulation 1.84
15 hsa-mir-22 miRNA microarray quantitative PCR miRNA overexpression 1.93
16 hsa-mir-221 miRNA microarray quantitative PCR miRNA overexpression 2.5
17 hsa-mir-222 miRNA microarray quantitative PCR miRNA overexpression 2.09
18 hsa-mir-24-1 miRNA microarray miRNA overexpression 1.36
19 hsa-mir-345 miRNA microarray miRNA overexpression 3.23
20 hsa-mir-34a miRNA microarray miRNA overexpression 2.08
21 hsa-mir-361 miRNA microarray miRNA overexpression 2.27
22 hsa-mir-378 miRNA microarray miRNA overexpression 1.33
23 hsa-mir-99a miRNA microarray miRNA overexpression 2.51

Detailed information about selected miRNA


hsa-mir-103-1
Authors' designation: hsa-miR-103;
miRNA microarray
miRNA overexpression
1.62    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

Comments


General comment: In addition, the authors mentioned ambi-mir-7037 with fold change 1.56. Folate deficiency and exposure to sodium arsenite led to global increases in miRNA expression. No significant alteration in miRNA expression was found in cells treated with (gamma)-irradiation.