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General information


494
18977327
Homo sapiens (9606)
tumor angiogenesis
Glioma cells have a high capacity to induce angiogenesis and were used to stimulate angiogenesis in primary human microvascular endothelial cells (HBMVECs) isolated from normal human brain. microRNA expression profile was analysed in HBMVECs after addition of Glioma cells and compared to the expression profile without Glioma cells.

Study information


Bioprocess study
cerebrovascular endothelial cell

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-101-1 miRNA microarray miRNA downregulation 2.703
2 hsa-mir-103-1 miRNA microarray miRNA downregulation 4.348
3 hsa-mir-125b-1 miRNA microarray miRNA downregulation 6.25
4 hsa-mir-126 miRNA microarray miRNA downregulation 4.545
5 hsa-mir-181a-1 miRNA microarray miRNA downregulation 2.564
6 hsa-mir-21 miRNA microarray miRNA downregulation 3.333
7 hsa-mir-22 miRNA microarray miRNA downregulation 3.333
8 hsa-mir-23b miRNA microarray miRNA downregulation 3.704
9 hsa-mir-27a miRNA microarray miRNA downregulation 3.226
10 hsa-mir-296 miRNA microarray quantitative PCR miRNA overexpression 1.96 HGS
11 hsa-mir-29a miRNA microarray miRNA downregulation 5.263
12 hsa-mir-30b miRNA microarray miRNA downregulation 3.226
13 hsa-mir-31 miRNA microarray miRNA downregulation 3.704

Detailed information about selected miRNA


hsa-mir-101-1
Authors' designation: hsa-miR-101;
miRNA microarray
miRNA downregulation
2.703    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

Comments


General comment: Glioma cells can influence miRNA expression in endothelial blood vessel cells (HBMVECs) isolated from human brain.