General search


List as:
Entries miRNAs
Search type:
Fuzzy Strict


help

Specific search


List as:
Entries miRNAs
Search type:
Fuzzy Strict

help
About phenomir
Download

List all entries
List all diseases
List all miRNAs

Home

© 2009 - Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH) Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany


Imprint


Disclaimer:
MIPS Databases and associated information are protected by copyright. This server and its associated data and services are for academic, non-commercial use only. The Helmholtz Zentrum München has no liability for the use of results, data or information which have been provided through this server. Neither the use for commercial purposes, nor the redistribution of MIPS database files to third parties nor the distribution of parts of files or derivative products to any third parties is permitted.

Home > List > Detailed view

General information


402
18223217
Homo sapiens (9606)
disease
Hepatocellular carcinoma
Hepatocellular carcinoma, associated with hepatitis B/C viral infection and cirrhosis

Study information


Patient study phenotype-control
12
12
The authors analysed adjacent benign tissue of HCC (hepatocellular carcinoma) V(+) C(+) patients, refering to cirrhosis (C) and viral hepatitis infection (V), versus 12 normal liver tissues.
liver

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7a-1 quantitative PCR miRNA overexpression 3.3
2 hsa-let-7a-2 quantitative PCR miRNA overexpression 2.8
3 hsa-let-7a-3 quantitative PCR miRNA overexpression 6.7
4 hsa-let-7d quantitative PCR miRNA overexpression 3
5 hsa-let-7f-1 quantitative PCR miRNA overexpression 3.2
6 hsa-mir-125b-1 quantitative PCR miRNA overexpression 3.2
7 hsa-mir-128-1 quantitative PCR miRNA overexpression 2.1
8 hsa-mir-135a-1 quantitative PCR miRNA overexpression 3.5
9 hsa-mir-135a-2 quantitative PCR miRNA overexpression 3.5
10 hsa-mir-147 quantitative PCR miRNA overexpression 5.3
11 hsa-mir-181a-1 quantitative PCR miRNA overexpression 3.2
12 hsa-mir-181b-1 quantitative PCR miRNA overexpression 2.4
13 hsa-mir-181b-2 quantitative PCR miRNA overexpression 2.4
14 hsa-mir-181c quantitative PCR miRNA overexpression 3.2
15 hsa-mir-186 quantitative PCR miRNA overexpression 2.2
16 hsa-mir-199a-2 quantitative PCR miRNA overexpression 2.4
17 hsa-mir-208a quantitative PCR miRNA overexpression 2.3
18 hsa-mir-214 quantitative PCR miRNA overexpression 1.9
19 hsa-mir-221 quantitative PCR miRNA overexpression 3.6
20 hsa-mir-23a quantitative PCR miRNA overexpression 2.4
21 hsa-mir-23b quantitative PCR miRNA overexpression 2.4
22 hsa-mir-370 quantitative PCR miRNA overexpression 2.5
23 hsa-mir-371 quantitative PCR miRNA overexpression 2.8
24 hsa-mir-93 quantitative PCR miRNA overexpression 3.5

Detailed information about selected miRNA


hsa-let-7a-1
quantitative PCR
miRNA overexpression
3.3    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

Comments


General comment: The authors show that a large number of miRNAs have increased expression in the hepatitis-positive and cirrhotic specimens compared with the liver tissues that developed HCC in the context of a histologically normal liver or in normal liver not associated with HCCs.