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General information

Homo sapiens (9606)
Leukemia, acute myeloid

Study information

Patient study phenotype-phenotype
Phenotype 1: Flt3-ITD mutant (n=20); Phenotype 2: all remaining AML patients in the cohort (n=195);
bone marrow

miRNA list

Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-10b quantitative PCR miRNA overexpression 4.71
2 hsa-mir-130a quantitative PCR miRNA downregulation 1.83
3 hsa-mir-135a-1 quantitative PCR miRNA overexpression 1.97
4 hsa-mir-143 quantitative PCR miRNA downregulation 2.74
5 hsa-mir-145 quantitative PCR miRNA downregulation 2.41
6 hsa-mir-155 quantitative PCR miRNA overexpression 4.92
7 hsa-mir-182 quantitative PCR miRNA downregulation 2.51
8 hsa-mir-203 quantitative PCR miRNA downregulation 1.18
9 hsa-mir-214 quantitative PCR miRNA downregulation 1.3
10 hsa-mir-30a quantitative PCR miRNA downregulation 2.73
11 hsa-mir-338 quantitative PCR miRNA downregulation 2.71
12 hsa-mir-511-1 quantitative PCR miRNA overexpression 2.78

Detailed information about selected miRNA

quantitative PCR
miRNA overexpression

Genes associated with selected miRNA

target gene regulation mechanism of regulation comment


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