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General information


389
18337557
Homo sapiens (9606)
disease
Leukemia, acute myeloid

Study information


Patient study phenotype-phenotype
Phenotype 1: NPM1 mutant (n=68); Phenotype 2: all remaining AML patients in the cohort (n=147);
bone marrow

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7b quantitative PCR miRNA overexpression 2.25
2 hsa-mir-10a quantitative PCR miRNA overexpression 5.31
3 hsa-mir-10b quantitative PCR miRNA overexpression 5.19
4 hsa-mir-126 quantitative PCR miRNA downregulation 4
5 hsa-mir-127 quantitative PCR miRNA downregulation 33.333
6 hsa-mir-130a quantitative PCR miRNA downregulation 3.571
7 hsa-mir-134 quantitative PCR miRNA downregulation 5.556
8 hsa-mir-135a-1 quantitative PCR miRNA overexpression 2.41
9 hsa-mir-143 quantitative PCR miRNA downregulation 2.041
10 hsa-mir-146a quantitative PCR miRNA downregulation 2.083
11 hsa-mir-151 quantitative PCR miRNA downregulation 2.326
12 hsa-mir-152 quantitative PCR miRNA overexpression 2.3
13 hsa-mir-193b quantitative PCR miRNA downregulation 2.439
14 hsa-mir-196a-1 quantitative PCR miRNA overexpression 2.25
15 hsa-mir-196b quantitative PCR miRNA overexpression 2.31
16 hsa-mir-203 quantitative PCR miRNA downregulation 3.226
17 hsa-mir-224 quantitative PCR miRNA downregulation 6.667
18 hsa-mir-299 quantitative PCR miRNA downregulation 4.348
19 hsa-mir-320a quantitative PCR miRNA downregulation 2.128
20 hsa-mir-323 quantitative PCR miRNA downregulation 2
21 hsa-mir-335 quantitative PCR miRNA downregulation 3.226
22 hsa-mir-365-1 quantitative PCR miRNA downregulation 2.5
23 hsa-mir-370 quantitative PCR miRNA downregulation 5.882
24 hsa-mir-376a-1 quantitative PCR miRNA downregulation 11.111
25 hsa-mir-379 quantitative PCR miRNA downregulation 6.25
26 hsa-mir-382 quantitative PCR miRNA downregulation 10
27 hsa-mir-424 quantitative PCR miRNA downregulation 12.5
28 hsa-mir-432 quantitative PCR miRNA downregulation 6.667
29 hsa-mir-433 quantitative PCR miRNA downregulation 4.348
30 hsa-mir-450a-1 quantitative PCR miRNA downregulation 2.5
31 hsa-mir-451 quantitative PCR miRNA downregulation 4.545
32 hsa-mir-485 quantitative PCR miRNA downregulation 3.571
33 hsa-mir-494 quantitative PCR miRNA downregulation 2.326
34 hsa-mir-497 quantitative PCR miRNA downregulation 2.083
35 hsa-mir-511-1 quantitative PCR miRNA downregulation 2.174
36 hsa-mir-99b quantitative PCR miRNA downregulation 2

Detailed information about selected miRNA


hsa-let-7b
quantitative PCR
miRNA overexpression
2.25    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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