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General information


386
18337557
Homo sapiens (9606)
disease
Leukemia, acute myeloid

Study information


Patient study phenotype-phenotype
Phenotype 1: t.(8;21) mutant (n=12); Phenotype 2: all remaining AML patients in the cohort (n=203);
bone marrow

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7b quantitative PCR miRNA downregulation 3.846
2 hsa-let-7c quantitative PCR miRNA downregulation 5
3 hsa-mir-1-1 quantitative PCR miRNA downregulation 16.667
4 hsa-mir-100 quantitative PCR miRNA downregulation 14.286
5 hsa-mir-107 quantitative PCR miRNA downregulation 2.128
6 hsa-mir-10b quantitative PCR miRNA downregulation 100
7 hsa-mir-125b-1 quantitative PCR miRNA downregulation 14.286
8 hsa-mir-126 quantitative PCR miRNA overexpression 5.48
9 hsa-mir-133a-1 quantitative PCR miRNA downregulation 25
10 hsa-mir-133b quantitative PCR miRNA downregulation 33.333
11 hsa-mir-135a-1 quantitative PCR miRNA downregulation 9.091
12 hsa-mir-148a quantitative PCR miRNA downregulation 11.111
13 hsa-mir-152 quantitative PCR miRNA downregulation 6.25
14 hsa-mir-182 quantitative PCR miRNA downregulation 5.263
15 hsa-mir-187 quantitative PCR miRNA downregulation 2.941
16 hsa-mir-188 quantitative PCR miRNA downregulation 2.222
17 hsa-mir-196a-1 quantitative PCR miRNA downregulation 100
18 hsa-mir-19a quantitative PCR miRNA downregulation 2
19 hsa-mir-20b quantitative PCR miRNA downregulation 2.857
20 hsa-mir-210 quantitative PCR miRNA downregulation 4.167
21 hsa-mir-221 quantitative PCR miRNA downregulation 2.128
22 hsa-mir-224 quantitative PCR miRNA downregulation 33.333
23 hsa-mir-338 quantitative PCR miRNA downregulation 2.439
24 hsa-mir-339 quantitative PCR miRNA downregulation 4
25 hsa-mir-342 quantitative PCR miRNA downregulation 2.632
26 hsa-mir-500 quantitative PCR miRNA downregulation 6.25
27 hsa-mir-501 quantitative PCR miRNA downregulation 3.846
28 hsa-mir-502 quantitative PCR miRNA downregulation 4.348
29 hsa-mir-9-1 quantitative PCR miRNA downregulation 100
30 hsa-mir-99a quantitative PCR miRNA downregulation 14.286

Detailed information about selected miRNA


hsa-let-7b
quantitative PCR
miRNA downregulation
3.846    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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