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General information


384
18337557
Homo sapiens (9606)
disease
Leukemia, acute myeloid

Study information


Patient study phenotype-phenotype
Phenotype 1: Inv(16) mutant (n=15); Phenotype 2: all remaining AML patients in the cohort (n=200);
bone marrow

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7b quantitative PCR miRNA downregulation 2.941
2 hsa-mir-10a quantitative PCR miRNA downregulation 100
3 hsa-mir-10b quantitative PCR miRNA downregulation 50
4 hsa-mir-127 quantitative PCR miRNA downregulation 50
5 hsa-mir-135a-1 quantitative PCR miRNA downregulation 12.5
6 hsa-mir-135b quantitative PCR miRNA downregulation 3.846
7 hsa-mir-148a quantitative PCR miRNA downregulation 2.857
8 hsa-mir-155 quantitative PCR miRNA downregulation 2.439
9 hsa-mir-192 quantitative PCR miRNA downregulation 2.128
10 hsa-mir-193a quantitative PCR miRNA overexpression 2.12
11 hsa-mir-196a-1 quantitative PCR miRNA downregulation 5.882
12 hsa-mir-196b quantitative PCR miRNA downregulation 5.556
13 hsa-mir-199b quantitative PCR miRNA overexpression 2.57
14 hsa-mir-218-1 quantitative PCR miRNA downregulation 2.941
15 hsa-mir-296 quantitative PCR miRNA downregulation 2.222
16 hsa-mir-335 quantitative PCR miRNA overexpression 2.47
17 hsa-mir-365-1 quantitative PCR miRNA overexpression 2.51
18 hsa-mir-424 quantitative PCR miRNA overexpression 2.63
19 hsa-mir-432 quantitative PCR miRNA downregulation 9.091
20 hsa-mir-511-1 quantitative PCR miRNA overexpression 2.36

Detailed information about selected miRNA


hsa-let-7b
quantitative PCR
miRNA downregulation
2.941    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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