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General information

Homo sapiens (9606)
Cervical cancer, somatic

Study information

Cell culture study
The HPV-18-positive cell line HeLa was compared to the normal cervix.
HeLa cell

miRNA list

Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-1-1 miRNA microarray miRNA downregulation 9.3
2 hsa-mir-106a miRNA microarray miRNA overexpression 12.2
3 hsa-mir-106b miRNA microarray miRNA overexpression 4.4
4 hsa-mir-133b miRNA microarray miRNA downregulation 7.6
5 hsa-mir-139 miRNA microarray miRNA downregulation 3.3
6 hsa-mir-143 miRNA microarray quantitative PCR, Northern Blot miRNA downregulation 6.8
7 hsa-mir-145 miRNA microarray quantitative PCR, Northern Blot miRNA downregulation 9.1
8 hsa-mir-17 miRNA microarray miRNA overexpression 6.6
9 hsa-mir-182 miRNA microarray miRNA overexpression 6.5
10 hsa-mir-183 miRNA microarray miRNA overexpression 5.2
11 hsa-mir-196a-1 miRNA microarray miRNA overexpression 6.2
12 hsa-mir-199a-1 miRNA microarray miRNA downregulation 5.7
13 hsa-mir-200a miRNA microarray miRNA downregulation 4.6
14 hsa-mir-200c miRNA microarray miRNA downregulation 3.7
15 hsa-mir-205 miRNA microarray miRNA downregulation 8
16 hsa-mir-214 miRNA microarray miRNA downregulation 6.7
17 hsa-mir-224 miRNA microarray miRNA overexpression 3.6
18 hsa-mir-25 miRNA microarray miRNA overexpression 4.5
19 hsa-mir-30a miRNA microarray miRNA overexpression 5.6
20 hsa-mir-31 miRNA microarray miRNA overexpression 13.7
21 hsa-mir-329-1 miRNA microarray miRNA downregulation 4.6
22 hsa-mir-376c miRNA microarray miRNA downregulation 5.6
23 hsa-mir-451 miRNA microarray miRNA downregulation 5.3
24 hsa-mir-93 miRNA microarray miRNA overexpression 8.9

Detailed information about selected miRNA

Authors' designation: hsa-miR-1;
miRNA microarray
miRNA downregulation

Genes associated with selected miRNA

target gene regulation mechanism of regulation comment


General comment: The following microRNAs from supplementary table 3 could not be annotated: ambi-miR-13143, ambi-miR-9630, ambi-miR-7029.