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General information


24
17563749
Homo sapiens (9606)
disease
Cancer
Thyroid carcinoma, anaplastic
Thyroid carcinomas comprise a broad spectrum of tumors with different clinical behaviors. On the one side, there are occult papillary carcinomas (PTC), slow growing and clinically silent, and on the other side, rapidly growing anaplastic carcinomas (ATC), which are among the most lethal human neoplasms. Comparison of miRNA profile between occult papillary carcinomas and anaplastic carcinomas (ATC) in this study does not show any significant similarity.

Study information


Patient study phenotype-control
10
10
thyroid gland

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-125a miRNA microarray miRNA downregulation 2.1
2 hsa-mir-125b-1 miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 3.7
3 hsa-mir-125b-2 miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 3.1
4 hsa-mir-138-1 miRNA microarray miRNA downregulation 2.3
5 hsa-mir-224 miRNA microarray miRNA downregulation 2.7
6 hsa-mir-25 miRNA microarray miRNA downregulation 2.2
7 hsa-mir-26a-1 miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 3.3
8 hsa-mir-30a miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 3
9 hsa-mir-30d miRNA microarray Northern Blot, quantitative PCR miRNA downregulation 4.5
10 hsa-mir-92a-2 miRNA microarray miRNA downregulation 2.3

Detailed information about selected miRNA


hsa-mir-125a
miRNA microarray
miRNA downregulation
2.1    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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