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General information


171
17283129
Homo sapiens (9606)
disease
Neuroblastoma

Study information


Patient study phenotype-phenotype
Phenotype 1: neuroblastoma tumor, MYCN-amplified (MNA) (n=12); Phenotype 2: neuroblastoma tumor, with hemizygous loss of chromosome 11q material; Both tumor subtypes are associated with poor survival.
neuroblastoma cell
Tissue was isolated from primary neuroblastoma tumors without further specification.

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7a-1 quantitative PCR miRNA overexpression 2.4
2 hsa-let-7a-2 quantitative PCR miRNA overexpression 2.4
3 hsa-let-7a-3 quantitative PCR miRNA overexpression 2.4
4 hsa-let-7b quantitative PCR miRNA overexpression 3.99
5 hsa-mir-141 quantitative PCR miRNA downregulation 3.85
6 hsa-mir-150 quantitative PCR miRNA downregulation 2.94
7 hsa-mir-181a-2 quantitative PCR miRNA overexpression 3.75
8 hsa-mir-181b-1 quantitative PCR miRNA overexpression 8.85
9 hsa-mir-181b-2 quantitative PCR miRNA overexpression 8.85
10 hsa-mir-184 quantitative PCR miRNA downregulation 2.38
11 hsa-mir-200c quantitative PCR miRNA downregulation 2.22
12 hsa-mir-216a quantitative PCR miRNA downregulation 3.7
13 hsa-mir-301a quantitative PCR miRNA downregulation 2.7
14 hsa-mir-323 quantitative PCR miRNA downregulation 3.7
15 hsa-mir-331 quantitative PCR miRNA downregulation 1.59

Detailed information about selected miRNA


hsa-let-7a-1
quantitative PCR
miRNA overexpression
2.4    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

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