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General information


164
18316553
Homo sapiens (9606)
disease
Breast cancer

Study information


Patient study phenotype-control
219
10
breast

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-mir-21 quantitative PCR miRNA microarray miRNA overexpression 1.31
2 hsa-mir-210 quantitative PCR miRNA microarray miRNA overexpression 5.48 HIF1A

Detailed information about selected miRNA


hsa-mir-21
quantitative PCR
miRNA microarray
miRNA overexpression
1.31    

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

Comments


General comment: The authors show that hsa-miR-210 overexpression is induced by hypoxia in a HIF-1alpha and VHL-dependent fashion and its expression levels in breast cancer samples are an independent prognostic factor.