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Home > List > Detailed view

General information


132
16530703
Homo sapiens (9606)
disease
Lung cancer

Study information


Patient study phenotype-control
104
104
lung

miRNA list


Nr miRNA Method Further methods Evidence Foldchange Genes
1 hsa-let-7a-2 miRNA microarray miRNA downregulation
2 hsa-mir-101-1 miRNA microarray miRNA downregulation
3 hsa-mir-106a miRNA microarray miRNA overexpression
4 hsa-mir-124-1 miRNA microarray miRNA downregulation
5 hsa-mir-124-3 miRNA microarray miRNA downregulation
6 hsa-mir-125a miRNA microarray miRNA downregulation
7 hsa-mir-126 miRNA microarray quantitative PCR miRNA downregulation
8 hsa-mir-140 miRNA microarray miRNA downregulation
9 hsa-mir-143 miRNA microarray miRNA downregulation
10 hsa-mir-145 miRNA microarray miRNA downregulation
11 hsa-mir-146a miRNA microarray miRNA overexpression
12 hsa-mir-150 miRNA microarray miRNA overexpression
13 hsa-mir-155 miRNA microarray miRNA overexpression
14 hsa-mir-17 miRNA microarray miRNA overexpression
15 hsa-mir-181c miRNA microarray miRNA downregulation
16 hsa-mir-191 miRNA microarray miRNA overexpression
17 hsa-mir-192 miRNA microarray miRNA overexpression
18 hsa-mir-197 miRNA microarray miRNA overexpression
19 hsa-mir-198 miRNA microarray miRNA downregulation
20 hsa-mir-199b miRNA microarray miRNA downregulation
21 hsa-mir-203 miRNA microarray miRNA overexpression
22 hsa-mir-205 miRNA microarray quantitative PCR miRNA overexpression
23 hsa-mir-21 miRNA microarray quantitative PCR miRNA overexpression
24 hsa-mir-210 miRNA microarray miRNA overexpression
25 hsa-mir-212 miRNA microarray miRNA overexpression
26 hsa-mir-214 miRNA microarray miRNA overexpression
27 hsa-mir-216a miRNA microarray miRNA downregulation
28 hsa-mir-218-2 miRNA microarray miRNA downregulation
29 hsa-mir-219-1 miRNA microarray miRNA downregulation
30 hsa-mir-220a miRNA microarray miRNA downregulation
31 hsa-mir-224 miRNA microarray miRNA downregulation
32 hsa-mir-24-2 miRNA microarray miRNA overexpression
33 hsa-mir-26a-1 miRNA microarray miRNA downregulation
34 hsa-mir-27b miRNA microarray miRNA downregulation
35 hsa-mir-29b-2 miRNA microarray miRNA downregulation
36 hsa-mir-30a miRNA microarray miRNA downregulation
37 hsa-mir-32 miRNA microarray miRNA downregulation
38 hsa-mir-33a miRNA microarray miRNA downregulation
39 hsa-mir-9-1 miRNA microarray miRNA downregulation
40 hsa-mir-95 miRNA microarray miRNA downregulation

Detailed information about selected miRNA


hsa-let-7a-2
Authors' designation: hsa-let-7a-2-prec; high hsa-mir-155 and low hsa-let-7a-2 expression correlated with poor survival.
miRNA microarray
miRNA downregulation
   

Genes associated with selected miRNA


target gene regulation mechanism of regulation comment

Comments


General comment: The authors showed that the lung adenocarcinoma patients with either high hsa-mir-155 or reduced hsa-let-7a-2 expression had a poorer survival than the patients with low hsa-mir-155 or high hsa-let-7a-2 expression, respectively. The difference in the prognosis of these two groups was statistically significant for hsa-mir-155 and marginally significant for hsa-let-7a-2.