Thickened skin

Symptom Information:

Symptom ID: HPO:0001072
Synonyms:
Diffusely thickened skin [HPO:0001072]
Pachydermia [HPO:0001072]
Thick skin [Orphanet:23400]
Pachyderma (morphologic abnormality) [Orphanet:23400]
Thick skin (finding) [Orphanet:23400]
Thickness of skin (observable entity) [Orphanet:23400]
Thickening of skin (disorder) [Orphanet:23400]
Pachyderma [Orphanet:23400]
Thickening of skin [Orphanet:23400]
Thickness of skin [Orphanet:23400]
Pachydermia [OMIM:Pachydermia]
Thickened skin [OMIM:Thickened skin]
Thick skin/pachydermia/orange skin [Orphanet:23400]
Skin thickening [HPO:0001072]
Skin thickening [Orphanet:23400]
Skin hypertrophy [MedDRA:10040867]
Dorsi manus hypertrophy [MedDRA:10040867]
Finger joint skin hypertrophy [MedDRA:10040867]
Hypertrophy of skin [MedDRA:10040867]
Hypertrophy skin [MedDRA:10040867]
Skin thickening [MedDRA:10040867]
Pachyderma [OMIM:Pachyderma]
Skin thickening [OMIM:Skin thickening]
Thick skin [OMIM:Thick skin]
Thick skin (66%) [OMIM:Thick skin (66%)]
Thick skin (74%) [OMIM:Thick skin (74%)]
Orange peel skin [Orphanet:23400]
'Orange peel' skin [OMIM:'Orange peel' skin]
'Orange peel' skin (large pores) [OMIM:'Orange peel' skin (large pores)]
Quality:
Cross references:
Orphanet:23400 "Thick skin/pachydermia/orange skin" [Orphanet:23400]
OMIM: "Pachydermia" [OMIM:Pachydermia]
OMIM: "Thickened skin" [OMIM:Thickened skin]
OMIM: "Pachyderma" [OMIM:Pachyderma]
OMIM: "Skin thickening" [OMIM:Skin thickening]
OMIM: "Thick skin" [OMIM:Thick skin]
OMIM: "Thick skin (66%)" [OMIM:Thick skin (66%)]
OMIM: "Thick skin (74%)" [OMIM:Thick skin (74%)]
OMIM: "'Orange peel' skin" [OMIM:'Orange peel' skin]
OMIM: "'Orange peel' skin (large pores)" [OMIM:'Orange peel' skin (large pores)]
UMLS:C0423758 "Thick skin" [Orphanet:23400]
UMLS:C0334008 "Pachyderma" [Orphanet:23400]
UMLS:C0241165 "Thickening of skin" [Orphanet:23400]
UMLS:C0423756 "Thickness of skin" [Orphanet:23400]
Is a (Direct Parents):
MedDRA Skin hyperplasias and hypertrophies
HPO         Abnormality of skin morphology
Orphanet Abnormality of the skin
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of the skin(HPO:0000951)
             Generalized abnormality of skin(HPO:0011354)
                Abnormality of skin morphology(HPO:0011121)
                   Thickened skin(HPO:0001072)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Cornification and dystrophic skin disorders(MedDRA:10011063)
       Skin hyperplasias and hypertrophies(MedDRA:10040866)
          Thickened skin(HPO:0001072)
Database Frequency: 87 / 7739
Resource:

All diseases associated with this symptom:

Absence of fingerprints - congenital milia (Orphanet:1658)
Acquired epidermolysis bullosa (Orphanet:46487)
Acquired hypertrichosis lanuginosa (Orphanet:2221)
Acrocephalopolydactyly (Orphanet:221054)
Acrocephalosyndactyly (Orphanet:946)
Acromegaloid facial appearance syndrome (Orphanet:965)
Acromegaly (Orphanet:963)
Acromicric dysplasia (Orphanet:969)
Acroosteolysis, dominant type (Orphanet:955)
Alström syndrome (Orphanet:64)
Berardinelli-Seip congenital lipodystrophy (Orphanet:528)
Blepharonasofacial malformation syndrome (Orphanet:1252)
CREST syndrome (Orphanet:90290)
Combined oxidative phosphorylation defect type 11 (Orphanet:324535)
Congenital erythropoietic porphyria (Orphanet:79277)
Congenital hypothyroidism (Orphanet:442)
Cranio-osteoarthropathy (Orphanet:1525)
Cutaneous mastocytoma (Orphanet:79455)
Cyprus facial-neuromusculoskeletal syndrome (Orphanet:2674)
DERMATOLEUKODYSTROPHY (OMIM:221790)
DWARFISM WITH STIFF JOINTS AND OCULAR ABNORMALITIES (OMIM:127200)
Dahlberg-Borer-Newcomer syndrome (Orphanet:1563)
Darier disease (Orphanet:218)
Dermato-cardio-skeletal syndrome, Borrone type (Orphanet:1266)
Dermatofibrosarcoma protuberans (Orphanet:31112)
Dermatoleukodystrophy (Orphanet:1659)
Diffuse cutaneous mastocytosis (Orphanet:79456)
Diffuse palmoplantar keratoderma-acrocyanosis syndrome (Orphanet:86918)
Familial Dupuytren contracture (Orphanet:79142)
Fetal Gaucher disease (Orphanet:85212)
GELEOPHYSIC DYSPLASIA 1 (OMIM:231050)
GELEOPHYSIC DYSPLASIA 2 (OMIM:614185)
Gaucher disease type 2 (Orphanet:77260)
Geleophysic dysplasia (Orphanet:2623)
Glaucoma - ectopia - microspherophakia - stiff joints - short stature (Orphanet:2084)
Haim-Munk syndrome (Orphanet:2342)
Hereditary palmoplantar keratoderma (Orphanet:79357)
Hereditary sensory and autonomic neuropathy type 4 (Orphanet:642)
Hermansky-Pudlak syndrome (Orphanet:79430)
Hurler syndrome (Orphanet:93473)
Hurler-Scheie syndrome (Orphanet:93476)
Inherited epidermolysis bullosa (Orphanet:79361)
Intestinal lymphangiectasia (Orphanet:36204)
Isolated punctate palmoplantar keratoderma (Orphanet:2338)
Juvenile idiopathic arthritis (Orphanet:92)
KID syndrome (Orphanet:477)
Keratosis follicularis spinulosa decalvans (Orphanet:2340)
Leprechaunism (Orphanet:508)
Leri pleonosteosis (Orphanet:2900)
Lethal restrictive dermopathy (Orphanet:1662)
Lipodystrophy due to peptidic growth factors deficiency (Orphanet:1979)
Lipoid proteinosis (Orphanet:530)
MUCOLIPIDOSIS III ALPHA/BETA (OMIM:252600)
Melorheostosis (Orphanet:2485)
Menkes disease (Orphanet:565)
Microcephaly - lymphedema - chorioretinopathy (Orphanet:2526)
Mucolipidosis type 3 (Orphanet:577)
Mucopolysaccharidosis type 2 (Orphanet:580)
Mucopolysaccharidosis type 2, attenuated form (Orphanet:217093)
Mucopolysaccharidosis type 2, severe form (Orphanet:217085)
Multiple benign circumferential skin creases on limbs (Orphanet:2505)
Mutilating palmoplantar keratoderma with periorificial keratotic plaques (Orphanet:659)
Myalgia-eosinophilia syndrome associated with tryptophan (Orphanet:2582)
Myhre syndrome (Orphanet:2588)
Neurocutaneous melanocytosis (Orphanet:2481)
Oculocutaneous albinism type 1B (Orphanet:79434)
Omenn syndrome (Orphanet:39041)
PMM2-CDG (Orphanet:79318)
POEMS syndrome (Orphanet:2905)
Pachydermoperiostosis (Orphanet:2796)
Palmoplantar keratoderma-spastic paralysis syndrome (Orphanet:2201)
Parana hard-skin syndrome (Orphanet:2812)
Pityriasis rubra pilaris (Orphanet:2897)
Primary cutis verticis gyrata (Orphanet:671)
Primary intestinal lymphangiectasia (Orphanet:90362)
Proteus syndrome (Orphanet:744)
Rabson-Mendenhall syndrome (Orphanet:769)
Scleroderma (Orphanet:801)
Secondary intestinal lymphangiectasia (Orphanet:90363)
Split hand - urinary anomalies - spina bifida (Orphanet:2437)
Stern-Lubinsky-Durrie syndrome (Orphanet:3194)
Stiff skin syndrome (Orphanet:2833)
Torg-Winchester syndrome (Orphanet:3460)
WEILL-MARCHESANI SYNDROME 1 (OMIM:277600)
Weill-Marchesani syndrome (Orphanet:3449)
X-linked dominant chondrodysplasia punctata (Orphanet:35173)
Xeroderma pigmentosum (Orphanet:910)