Hypothyroidism

Symptom Information:

Symptom ID: HPO:0000821
Synonyms:
Low T4 [HPO:0000821]
Hypothyroidism (disorder) [Orphanet:41210]
Hypothyroidism [Orphanet:41210]
Hypothyroidism [OMIM:Hypothyroidism]
Low T4 [OMIM:Low T4]
Hypothyroidy [Orphanet:41210]
Hypothyroidism [MedDRA:10021114]
Acquired hypothyroidism [MedDRA:10021114]
Acquired hypothyroidism other [MedDRA:10021114]
Iodine hypothyroidism [MedDRA:10021114]
Myxedema juvenile [MedDRA:10021114]
Other iatrogenic hypothyroidism [MedDRA:10021114]
Other specified acquired hypothyroidism [MedDRA:10021114]
Thyroid activity decreased [MedDRA:10021114]
Thyroid function decreased [MedDRA:10021114]
Unspecified hypothyroidism [MedDRA:10021114]
Myxoedema juvenile [MedDRA:10021114]
Latent hypothyroidism [MedDRA:10021114]
Subclinical hypothyroidism [MedDRA:10021114]
Hypothyroidism (20% of adults) [OMIM:Hypothyroidism (20% of adults)]
Hypothyroidism (30% patients) [OMIM:Hypothyroidism (30% patients)]
Hypothyroidism (autoimmune) [OMIM:Hypothyroidism (autoimmune)]
Hypothyroidism (if untreated) [OMIM:Hypothyroidism (if untreated)]
Hypothyroidism (in 1 of 3 siblings) [OMIM:Hypothyroidism (in 1 of 3 siblings)]
Hypothyroidism (in 2/4 patients) [OMIM:Hypothyroidism (in 2/4 patients)]
Hypothyroidism (less common) [OMIM:Hypothyroidism (less common)]
Hypothyroidism (rare) [OMIM:Hypothyroidism (rare)]
Hypothyroidism, subclinical [OMIM:Hypothyroidism, subclinical]
Quality:
Cross references:
Orphanet:41210 "Hypothyroidy" [Orphanet:41210]
OMIM: "Hypothyroidism" [OMIM:Hypothyroidism]
OMIM: "Low T4" [OMIM:Low T4]
OMIM: "Hypothyroidism (20% of adults)" [OMIM:Hypothyroidism (20% of adults)]
OMIM: "Hypothyroidism (30% patients)" [OMIM:Hypothyroidism (30% patients)]
OMIM: "Hypothyroidism (autoimmune)" [OMIM:Hypothyroidism (autoimmune)]
OMIM: "Hypothyroidism (if untreated)" [OMIM:Hypothyroidism (if untreated)]
OMIM: "Hypothyroidism (in 1 of 3 siblings)" [OMIM:Hypothyroidism (in 1 of 3 siblings)]
OMIM: "Hypothyroidism (in 2/4 patients)" [OMIM:Hypothyroidism (in 2/4 patients)]
OMIM: "Hypothyroidism (less common)" [OMIM:Hypothyroidism (less common)]
OMIM: "Hypothyroidism (rare)" [OMIM:Hypothyroidism (rare)]
OMIM: "Hypothyroidism, subclinical" [OMIM:Hypothyroidism, subclinical]
UMLS:C0020676 "Hypothyroidism" [HPO:0000821]
UMLS:C0020676 "Hypothyroidism" [Orphanet:41210]
Is a (Direct Parents):
MedDRA Thyroid hypofunction disorders
HPO         Abnormality of thyroid physiology
Orphanet Abnormality of the thyroid gland
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the endocrine system(HPO:0000818)
          Abnormality of the thyroid gland(HPO:0000820)
             Abnormality of thyroid physiology(HPO:0002926)
                Hypothyroidism(HPO:0000821)
MedDRA:
Endocrine disorders(MedDRA:10014698)
    Thyroid gland disorders(MedDRA:10043739)
       Thyroid hypofunction disorders(MedDRA:10043741)
          Hypothyroidism(HPO:0000821)
Database Frequency: 141 / 7739
Resource:

All diseases associated with this symptom:

17p11.2 microduplication syndrome (Orphanet:1713)
19p13.12 microdeletion syndrome (Orphanet:254346)
1p36 deletion syndrome (Orphanet:1606)
22q11.2 deletion syndrome (Orphanet:567)
46,XY disorder of sex development due to 17-beta-hydroxysteroid dehydrogenase 3 deficiency (Orphanet:752)
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET (OMIM:615952)
Aceruloplasminemia (Orphanet:48818)
Acetazolamide-responsive myotonia (Orphanet:99736)
Adiposis dolorosa (Orphanet:36397)
Albright hereditary osteodystrophy (Orphanet:665)
Alexander disease (Orphanet:58)
Allan-Herndon-Dudley syndrome (Orphanet:59)
Alström syndrome (Orphanet:64)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Ascher syndrome (Orphanet:1253)
Athyreosis (Orphanet:95713)
Autoimmune polyendocrinopathy type 2 (Orphanet:3143)
Autosomal recessive cutis laxa type 1 (Orphanet:90349)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
Bamforth syndrome (Orphanet:1226)
Bangstad syndrome (Orphanet:1227)
Bardet-Biedl syndrome 12 (OMIM:615989)
Beckwith-Wiedemann syndrome (Orphanet:116)
Beta-thalassemia major (Orphanet:231214)
Blepharophimosis-intellectual deficit syndrome, Ohdo type (Orphanet:2728)
Blepharophimosis-intellectual deficit syndrome, SBBYS type (Orphanet:3047)
CHARGE syndrome (Orphanet:138)
COWDEN SYNDROME 5 (OMIM:615108)
COWDEN SYNDROME 6 (OMIM:615109)
Castleman disease (Orphanet:160)
Cenani-Lenz syndrome (Orphanet:3258)
Central congenital hypothyroidism (Orphanet:226298)
Central precocious puberty (Orphanet:759)
Congenital atransferrinemia (Orphanet:1195)
Congenital hypothyroidism (Orphanet:442)
Congenital hypothyroidism due to developmental anomaly (Orphanet:95711)
Congenital hypothyroidism due to transplacental passage of maternal TSH-binding inhibitory antibodies (Orphanet:95715)
Congenital nephrotic syndrome, Finnish type (Orphanet:839)
Cowden syndrome (Orphanet:201)
Cronkhite-Canada syndrome (Orphanet:2930)
Cutis laxa (Orphanet:209)
Cutis marmorata telangiectatica congenita (Orphanet:1556)
Cystinosis (Orphanet:213)
DIGEORGE SYNDROME (OMIM:188400)
Dahlberg-Borer-Newcomer syndrome (Orphanet:1563)
Deafness - intellectual deficit, Martin-Probst type (Orphanet:85321)
Down syndrome (Orphanet:870)
Ectodermal dysplasia - intellectual deficit - central nervous system malformation (Orphanet:1812)
Fabry disease (Orphanet:324)
Familial thyroid dyshormonogenesis (Orphanet:95716)
Fetal iodine syndrome (Orphanet:1910)
Fragile X-associated tremor/ataxia syndrome (Orphanet:93256)
Fucosidosis (Orphanet:349)
Generalized congenital lipodystrophy with myopathy (Orphanet:228429)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
Hallermann-Streiff syndrome (Orphanet:2108)
Hawkinsinuria (Orphanet:2118)
Hypohidrotic ectodermal dysplasia - hypothyroidism - ciliary dyskinesia (Orphanet:1882)
Hypothyroidism due to TSH receptor mutations (Orphanet:90673)
Hypothyroidism due to deficient transcription factors involved in pituitary development or function (Orphanet:226307)
IMMUNODEFICIENCY 31C (OMIM:614162)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
Idiopathic congenital hypothyroidism (Orphanet:95717)
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (Orphanet:37042)
Immunodeficiency due to CD25 deficiency (Orphanet:169100)
Infantile axonal neuropathy (Orphanet:2679)
Isolated anterior cervical hypertrichosis (Orphanet:3387)
Isolated growth hormone deficiency type III (Orphanet:231692)
Johanson-Blizzard syndrome (Orphanet:2315)
Jung-Wolff-Back-Stahl syndrome (Orphanet:2321)
Koolen-De Vries syndrome (Orphanet:96169)
LIG4 syndrome (Orphanet:99812)
Lhermitte-Duclos disease (Orphanet:65285)
MELAS (Orphanet:550)
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 2 (OMIM:614114)
MYXEDEMA (OMIM:255900)
Megalocornea-intellectual deficit syndrome (Orphanet:2479)
Methimazole embryofetopathy (Orphanet:1923)
Microcephaly - seizures - intellectual deficit - heart disease (Orphanet:2519)
Microphthalmia with brain and digit anomalies (Orphanet:139471)
Monosomy 18p (Orphanet:1598)
Mosaic variegated aneuploidy syndrome (Orphanet:1052)
Mullerian duct anomalies - limb anomalies (Orphanet:2491)
Muscular pseudohypertrophy - hypothyroidism (Orphanet:2349)
NEUROLOGIC, ENDOCRINE, AND PANCREATIC DISEASE, MULTISYSTEM, INFANTILE-ONSET (OMIM:616263)
Noonan syndrome-like disorder with loose anagen hair (Orphanet:2701)
Obesity - colitis - hypothyroidism - cardiac hypertrophy - developmental delay (Orphanet:88643)
Oculofaciocardiodental syndrome (Orphanet:2712)
Omenn syndrome (Orphanet:39041)
PGM1-CDG (Orphanet:319646)
PHACE syndrome (Orphanet:42775)
PITUITARY DWARFISM WITH LARGE SELLA TURCICA (OMIM:262710)
PITUITARY HORMONE DEFICIENCY, COMBINED, 1 (OMIM:613038)
PITUITARY HORMONE DEFICIENCY, COMBINED, 2 (OMIM:262600)
PMM2-CDG (Orphanet:79318)
POEMS syndrome (Orphanet:2905)
PREMATURE OVARIAN FAILURE 10 (OMIM:612885)
Panhypopituitarism (Orphanet:90695)
Pendred syndrome (Orphanet:705)
Peripheral hypothyroidism (Orphanet:226310)
Peripheral resistance to thyroid hormones (Orphanet:97927)
Permanent congenital hypothyroidism (Orphanet:226292)
Pituitary stalk interruption syndrome (Orphanet:95496)
Primary congenital hypothyroidism (Orphanet:226295)
Primary congenital hypothyroidism without thyroid developmental anomaly (Orphanet:95714)
Proteus-like syndrome (Orphanet:2969)
Proximal myotonic myopathy (Orphanet:606)
Pseudohypoparathyroidism type 1A (Orphanet:79443)
Pseudohypoparathyroidism type 1C (Orphanet:79444)
Pseudoxanthoma elasticum (Orphanet:758)
Renal cysts and diabetes syndrome (Orphanet:93111)
Resistance to thyrotropin-releasing hormone syndrome (Orphanet:99832)
Retinohepatoendocrinologic syndrome (Orphanet:3087)
SPONDYLOENCHONDRODYSPLASIA WITH IMMUNE DYSREGULATION (OMIM:607944)
Schinzel-Giedion syndrome (Orphanet:798)
Short stature - craniofacial anomalies - genital hypoplasia (Orphanet:2994)
Short stature - pituitary and cerebellar defects - small sella turcica (Orphanet:85442)
Smith-Magenis syndrome (Orphanet:819)
Solitary median maxillary central incisor syndrome (Orphanet:2286)
Stüve-Wiedemann syndrome (Orphanet:3206)
THYROID DYSHORMONOGENESIS 1 (OMIM:274400)
THYROID DYSHORMONOGENESIS 2A (OMIM:274500)
THYROID DYSHORMONOGENESIS 3 (OMIM:274700)
THYROID DYSHORMONOGENESIS 4 (OMIM:274800)
THYROID DYSHORMONOGENESIS 5 (OMIM:274900)
THYROID DYSHORMONOGENESIS 6 (OMIM:607200)
TUBEROUS SCLEROSIS 1 (OMIM:191100)
TUBEROUS SCLEROSIS 2 (OMIM:613254)
Thyroid ectopia (Orphanet:95712)
Thyroid hemiagenesis (Orphanet:95719)
Thyroid hypoplasia (Orphanet:95720)
Timothy syndrome (Orphanet:65283)
Townes-Brocks syndrome (Orphanet:857)
Transient congenital hypothyroidism (Orphanet:178045)
Tuberous sclerosis (Orphanet:805)
Whipple disease (Orphanet:3452)
Williams syndrome (Orphanet:904)
Wolcott-Rallison syndrome (Orphanet:1667)
Wolfram syndrome 1 (OMIM:222300)
X-linked central congenital hypothyroidism with late-onset testicular enlargement (Orphanet:329235)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)