Excessive wrinkled skin

Symptom Information:

Symptom ID: HPO:0007392
Wrinkled skin [Orphanet:23150]
Wrinkled skin (finding) [Orphanet:23150]
Skin Wrinkling [Orphanet:23150]
Rippled skin [Orphanet:23150]
Skin wrinkling [Orphanet:23150]
Skin wrinkling [MedDRA:10040954]
Wrinkles [MedDRA:10040954]
Wrinkling [MedDRA:10040954]
Glabellar frown lines [MedDRA:10040954]
Frown lines [MedDRA:10040954]
Crow's feet [MedDRA:10040954]
Cross references:
HPO:0100678 "Premature skin wrinkling" [Orphanet:23150]
Orphanet:23150 "Rippled skin" [Orphanet:23150]
UMLS:C0037301 "Skin Wrinkling" [Orphanet:23150]
Is a (Direct Parents):
HPO         Abnormally lax or hyperextensible skin
MedDRA Skin dystrophies
HPO         Premature skin wrinkling
Orphanet Abnormality of the skin
Is a (Whole tree): HPO:
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of the skin(HPO:0000951)
             Generalized abnormality of skin(HPO:0011354)
                Prematurely aged appearance(HPO:0007495)
                   Premature skin wrinkling(HPO:0100678)
                      Excessive wrinkled skin(HPO:0007392)
                Abnormality of skin morphology(HPO:0011121)
                   Premature skin wrinkling(HPO:0100678)
                      Excessive wrinkled skin(HPO:0007392)
                   Abnormal elasticity of skin(HPO:0010647)
                      Abnormally lax or hyperextensible skin(HPO:0008067)
                         Excessive wrinkled skin(HPO:0007392)
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Cornification and dystrophic skin disorders(MedDRA:10011063)
       Skin dystrophies(MedDRA:10040837)
          Excessive wrinkled skin(HPO:0007392)
Database Frequency: 2 / 7739

All diseases associated with this symptom:

PYCR1-related DeBarsy syndrome (Orphanet:293633)
Transaldolase deficiency (Orphanet:101028)