Abnormal pyramidal signs

Symptom Information:

Symptom ID: HPO:0007256
Synonyms:
Corticospinal signs [HPO:0007256]
Pyramidal tract dysfunction [HPO:0007256]
Pyramidal tract signs [HPO:0007256]
Pyramidal symptoms [Orphanet:43310]
Pyramidal sign (finding) [Orphanet:43310]
Pyramidal sign [Orphanet:43310]
Corticospinal signs [OMIM:Corticospinal signs]
Pyramidal tract dysfunction [OMIM:Pyramidal tract dysfunction]
Pyramidal tract signs [OMIM:Pyramidal tract signs]
Pyramidal syndrome [Orphanet:43310]
Corticospinal signs (87% of patients in 1 report) [OMIM:Corticospinal signs (87% of patients in 1 report)]
Pyramidal signs [OMIM:Pyramidal signs]
Pyramidal signs (1 family) [OMIM:Pyramidal signs (1 family)]
Pyramidal signs (1 patient) [OMIM:Pyramidal signs (1 patient)]
Pyramidal signs (21% of patients) [OMIM:Pyramidal signs (21% of patients)]
Pyramidal signs (in 1 patient) [OMIM:Pyramidal signs (in 1 patient)]
Pyramidal signs (in some) [OMIM:Pyramidal signs (in some)]
Pyramidal signs (less common) [OMIM:Pyramidal signs (less common)]
Pyramidal symptoms [OMIM:Pyramidal symptoms]
Pyramidal syndrome [OMIM:Pyramidal syndrome]
Pyramidal tract dysfunction (juvenile-onset, less common) [OMIM:Pyramidal tract dysfunction (juvenile-onset, less common)]
Pyramidal tract signs (in some patients) [OMIM:Pyramidal tract signs (in some patients)]
Quality:
Cross references:
Orphanet:43310 "Pyramidal syndrome" [Orphanet:43310]
OMIM: "Corticospinal signs" [OMIM:Corticospinal signs]
OMIM: "Pyramidal tract dysfunction" [OMIM:Pyramidal tract dysfunction]
OMIM: "Pyramidal tract signs" [OMIM:Pyramidal tract signs]
OMIM: "Corticospinal signs (87% of patients in 1 report)" [OMIM:Corticospinal signs (87% of patients in 1 report)]
OMIM: "Pyramidal signs" [OMIM:Pyramidal signs]
OMIM: "Pyramidal signs (1 family)" [OMIM:Pyramidal signs (1 family)]
OMIM: "Pyramidal signs (1 patient)" [OMIM:Pyramidal signs (1 patient)]
OMIM: "Pyramidal signs (21% of patients)" [OMIM:Pyramidal signs (21% of patients)]
OMIM: "Pyramidal signs (in 1 patient)" [OMIM:Pyramidal signs (in 1 patient)]
OMIM: "Pyramidal signs (in some)" [OMIM:Pyramidal signs (in some)]
OMIM: "Pyramidal signs (less common)" [OMIM:Pyramidal signs (less common)]
OMIM: "Pyramidal symptoms" [OMIM:Pyramidal symptoms]
OMIM: "Pyramidal syndrome" [OMIM:Pyramidal syndrome]
OMIM: "Pyramidal tract dysfunction (juvenile-onset, less common)" [OMIM:Pyramidal tract dysfunction (juvenile-onset, less common)]
OMIM: "Pyramidal tract signs (in some patients)" [OMIM:Pyramidal tract signs (in some patients)]
UMLS:C0234132 "Pyramidal sign" [Orphanet:43310]
Is a (Direct Parents):
HPO         Abnormality of central motor function
Orphanet [DEL]Motor deficit/trouble
HPO         Gordon reflex
HPO         Oppenheim reflex
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Abnormality of central motor function(HPO:0011442)
                Abnormal pyramidal signs(HPO:0007256)
MedDRA:
Database Frequency: 116 / 7739
Resource:

All diseases associated with this symptom:

3-@METHYLGLUTACONIC ACIDURIA WITH CATARACTS, NEUROLOGIC INVOLVEMENT,AND NEUTROPENIA (OMIM:616271)
ALG13-CDG (Orphanet:324422)
AMYOTROPHIC LATERAL SCLEROSIS 10 WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA (OMIM:612069)
Adenylosuccinate lyase deficiency (Orphanet:46)
Adult neuronal ceroid lipofuscinosis (Orphanet:79262)
Adult polyglucosan body disease (Orphanet:206583)
Adult-onset autosomal dominant leukodystrophy (Orphanet:99027)
Alexander disease (Orphanet:58)
Alpha-N-acetylgalactosaminidase deficiency type 1 (Orphanet:79279)
Alpha-mannosidosis (Orphanet:61)
Ataxia with vitamin E deficiency (Orphanet:96)
Atypical Gaucher disease due to saposin C deficiency (Orphanet:309252)
Atypical progressive supranuclear palsy (Orphanet:99750)
Autosomal dominant Charcot-Marie-Tooth disease type 2A2 (Orphanet:99947)
Autosomal dominant spastic paraplegia type 13 (Orphanet:100994)
Autosomal dominant spastic paraplegia type 19 (Orphanet:100999)
Autosomal dominant spastic paraplegia type 4 (Orphanet:100985)
Autosomal recessive ataxia due to ubiquinone deficiency (Orphanet:139485)
Autosomal recessive cerebellar ataxia - saccadic intrusion (Orphanet:95434)
Autosomal recessive spastic paraplegia type 11 (Orphanet:2822)
Autosomal recessive spastic paraplegia type 28 (Orphanet:101008)
Autosomal recessive spastic paraplegia type 46 (Orphanet:320391)
Autosomal recessive spastic paraplegia type 7 (Orphanet:99013)
BASAL GANGLIA CALCIFICATION, IDIOPATHIC, 1 (OMIM:213600)
Behavioral variant of frontotemporal dementia (Orphanet:275864)
Behr syndrome (Orphanet:1239)
Behçet disease (Orphanet:117)
Bilateral frontoparietal polymicrogyria (Orphanet:101070)
Bilateral generalized polymicrogyria (Orphanet:208447)
Bilateral striopallidodentate calcinosis (Orphanet:1980)
Biotin-responsive basal ganglia disease (Orphanet:65284)
CADDS (Orphanet:369942)
CARASIL (Orphanet:199354)
CHOREOATHETOSIS, FAMILIAL INVERTED (OMIM:118750)
Cerebrotendinous xanthomatosis (Orphanet:909)
Coats plus syndrome (Orphanet:313838)
Cogan syndrome (Orphanet:1467)
Combined oxidative phosphorylation defect type 15 (Orphanet:319524)
Congenital cataracts - facial dysmorphism - neuropathy (Orphanet:48431)
Cystinosis (Orphanet:213)
Cystinuria (Orphanet:214)
Dentatorubral pallidoluysian atrophy (Orphanet:101)
Dihydropyrimidinuria (Orphanet:38874)
Dystonia 16 (Orphanet:210571)
ENCEPHALOPATHY, PROGRESSIVE, WITH OR WITHOUT LIPODYSTROPHY (OMIM:615924)
Ethylmalonic encephalopathy (Orphanet:51188)
Free sialic acid storage disease (Orphanet:834)
Friedreich ataxia 1 (OMIM:229300)
Fucosidosis (Orphanet:349)
Gaucher disease type 3 (Orphanet:77261)
Giant axonal neuropathy (Orphanet:643)
Hereditary sensory and autonomic neuropathy with spastic paraplegia (Orphanet:139578)
Huntington disease-like 3 (Orphanet:157946)
Hurler syndrome (Orphanet:93473)
Hurler-Scheie syndrome (Orphanet:93476)
Hyperornithinemia-hyperammonemia-homocitrullinuria (Orphanet:415)
Hypomyelination - congenital cataract (Orphanet:85163)
Hypotonia-speech impairment-severe cognitive delay syndrome (Orphanet:371364)
Infantile dystonia-parkinsonism (Orphanet:238455)
Infantile neuroaxonal dystrophy (Orphanet:35069)
Infantile-onset ascending hereditary spastic paralysis (Orphanet:293168)
Isolated cytochrome C oxidase deficiency (Orphanet:254905)
Juvenile amyotrophic lateral sclerosis (Orphanet:300605)
Juvenile neuronal ceroid lipofuscinosis (Orphanet:79264)
Juvenile parkinsonism with intellectual deficit due to DNAJC6 deficiency (Orphanet:352497)
Juvenile primary lateral sclerosis (Orphanet:247604)
Kufor-Rakeb syndrome (Orphanet:306674)
L-2-hydroxyglutaric aciduria (Orphanet:79314)
LEUKOENCEPHALOPATHY, BRAIN CALCIFICATIONS, AND CYSTS (OMIM:614561)
Leukoencephalopathy-palmoplantar keratoderma syndrome (Orphanet:2386)
Multiple osteochondromas (Orphanet:321)
Multiple sclerosis - ichthyosis - factor VIII deficiency (Orphanet:3151)
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A (OMIM:256600)
Nakajo-Nishimura syndrome (Orphanet:2615)
Neurodegeneration with brain iron accumulation due to C19orf12 mutation (Orphanet:289560)
Neurologic Waardenburg-Shah syndrome (Orphanet:163746)
Niemann-Pick disease type C (Orphanet:646)
Non-polyposis Turcot syndrome (Orphanet:99817)
Oculocerebral hypopigmentation syndrome, Cross type (Orphanet:2719)
PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE EARLY-ONSET (OMIM:260300)
PELIZAEUS-MERZBACHER DISEASE (OMIM:312080)
PORENCEPHALY 1 (OMIM:175780)
Pantothenate kinase-associated neurodegeneration (Orphanet:157850)
Parkinsonim due to ATP13A2 deficiency (Orphanet:314632)
Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity (Orphanet:53583)
Pelizaeus-Merzbacher-like disease (Orphanet:280270)
Pelizaeus-Merzbacher-like due to AIMP1 mutation (Orphanet:280293)
Peroxisomal acyl-CoA oxidase deficiency (Orphanet:2971)
Polyarteritis nodosa (Orphanet:767)
Progressive supranuclear palsy - parkinsonism (Orphanet:240085)
Pyruvate dehydrogenase E3-binding protein deficiency (Orphanet:255182)
Pyruvate dehydrogenase deficiency (Orphanet:765)
Refsum disease (Orphanet:773)
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1 (OMIM:606002)
Sandhoff disease (Orphanet:796)
Sandhoff disease, adult form (Orphanet:309169)
Sandhoff disease, infantile form (Orphanet:309155)
Sandhoff disease, juvenile form (Orphanet:309162)
Severe motor and intellectual disabilities-sensorineural deafness-dystonia syndrome (Orphanet:369939)
Sjögren-Larsson syndrome (Orphanet:816)
Spinocerebellar ataxia type 1 (Orphanet:98755)
Spinocerebellar ataxia type 10 (Orphanet:98761)
Spinocerebellar ataxia type 13 (Orphanet:98768)
Spinocerebellar ataxia type 20 (Orphanet:101110)
Spinocerebellar ataxia type 3 (Orphanet:98757)
Spinocerebellar ataxia type 5 (Orphanet:98766)
Spinocerebellar ataxia type 7 (Orphanet:94147)
Spinocerebellar ataxia type 8 (Orphanet:98760)
Spinocerebellar ataxia with axonal neuropathy type 2 (Orphanet:64753)
Thiamine-responsive encephalopathy (Orphanet:199348)
Tropical spastic paraparesis (Orphanet:289326)
Whipple disease (Orphanet:3452)
X-linked Charcot-Marie-Tooth disease type 3 (Orphanet:101077)
X-linked spastic paraplegia type 16 (Orphanet:100997)
X-linked spinocerebellar ataxia type 4 (Orphanet:85292)
[DEL] SPASTIC PARAPLEGIA 7, AUTOSOMAL RECESSIVE (OMIM:607259)