Reduced bone mineral density

Symptom Information:

Symptom ID: HPO:0004349
Decreased bone mineral density Z score [HPO:0004349]
Decreased bone mineral density Z score [OMIM:Decreased bone mineral density Z score]
Cross references:
OMIM: "Decreased bone mineral density Z score" [OMIM:Decreased bone mineral density Z score]
Is a (Direct Parents):
HPO         Abnormality of bone mineral density
Is a (Whole tree): HPO:
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal bone structure(HPO:0003330)
                Abnormality of bone mineral density(HPO:0004348)
                   Reduced bone mineral density(HPO:0004349)
Database Frequency: 165 / 7739

All diseases associated with this symptom:

46,XX gonadal dysgenesis (Orphanet:243)
ACTH-dependent Cushing syndrome (Orphanet:99892)
ACTH-independent macronodular adrenal hyperplasia (Orphanet:189427)
Acroosteolysis, dominant type (Orphanet:955)
Adrenomyodystrophy (Orphanet:977)
Aggressive systemic mastocytosis (Orphanet:98850)
Alexander disease (Orphanet:58)
Alkaptonuria (Orphanet:56)
Amish lethal microcephaly (Orphanet:99742)
Aromatase deficiency (Orphanet:91)
Atypical Rett syndrome (Orphanet:3095)
Autosomal dominant hyper-IgE syndrome (Orphanet:2314)
Autosomal dominant hypocalcemia (Orphanet:428)
Autosomal dominant hypophosphatemic rickets (Orphanet:89937)
Autosomal recessive cutis laxa type 1 (Orphanet:90349)
Autosomal recessive cutis laxa type 2 (Orphanet:90350)
Autosomal recessive malignant osteopetrosis (Orphanet:667)
Beta-thalassemia (Orphanet:848)
Beta-thalassemia major (Orphanet:231214)
Bird headed-dwarfism, Montreal type (Orphanet:2617)
Brittle cornea syndrome (Orphanet:90354)
Bruck syndrome (Orphanet:2771)
CINCA syndrome (Orphanet:1451)
Carney complex (Orphanet:1359)
Cholestasis - lymphedema (Orphanet:1414)
Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (Orphanet:90794)
Classic galactosemia (Orphanet:79239)
Classical homocystinuria (Orphanet:394)
Cleidocranial dysplasia (Orphanet:1452)
Cole-Carpenter syndrome (Orphanet:2050)
Complete androgen insensitivity syndrome (Orphanet:99429)
Congenital bile acid synthesis defect type 1 (Orphanet:79301)
Congenital bile acid synthesis defect type 2 (Orphanet:79303)
Congenital cataracts - facial dysmorphism - neuropathy (Orphanet:48431)
Congenital erythropoietic porphyria (Orphanet:79277)
Cooper-Jabs syndrome (Orphanet:1488)
Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis (Orphanet:94062)
Coxoauricular syndrome (Orphanet:1508)
Cranioectodermal dysplasia (Orphanet:1515)
Cushing disease (Orphanet:96253)
Cushing syndrome (Orphanet:553)
Cushing syndrome due to ectopic ACTH secretion (Orphanet:99889)
Cutaneous mastocytosis (Orphanet:66646)
Cutis marmorata telangiectatica congenita (Orphanet:1556)
Cyprus facial-neuromusculoskeletal syndrome (Orphanet:2674)
Cystinosis (Orphanet:213)
De Barsy syndrome (Orphanet:2962)
Dent disease type 1 (Orphanet:93622)
Disorder of bile acid synthesis (Orphanet:79168)
Disorder of sex development - intellectual deficit (Orphanet:2983)
Duchenne and Becker muscular dystrophy (Orphanet:262)
Dyskeratosis congenita (Orphanet:1775)
Ehlers-Danlos syndrome type 7B (Orphanet:99876)
Ehlers-Danlos syndrome, dermatosparaxis type (Orphanet:1901)
Ehlers-Danlos syndrome, progeroid type (Orphanet:75496)
Ehlers-Danlos syndrome, spondylocheirodysplastic type (Orphanet:157965)
Extensor tendons of finger anomalies (Orphanet:3294)
Fabry disease (Orphanet:324)
Fanconi anemia (Orphanet:84)
Farber lipogranulomatosis (Orphanet:333)
Free sialic acid storage disease (Orphanet:834)
Galactosemia (Orphanet:352)
Gaucher disease (Orphanet:355)
Gaucher disease type 1 (Orphanet:77259)
Generalized congenital lipodystrophy with myopathy (Orphanet:228429)
Geroderma osteodysplastica (Orphanet:2078)
Gnathodiaphyseal dysplasia (Orphanet:53697)
Grange syndrome (Orphanet:79094)
Hallermann-Streiff syndrome (Orphanet:2108)
Hemochromatosis type 2 (Orphanet:79230)
Hemochromatosis, type 2A (OMIM:602390)
Hereditary hypophosphatemic rickets with hypercalciuria (Orphanet:157215)
Hereditary sensory and autonomic neuropathy type 2 (Orphanet:970)
Hutchinson-Gilford progeria syndrome (Orphanet:740)
Hypertrichotic osteochondrodysplasia, Cantu type (Orphanet:1517)
Hypocalcemic vitamin D-resistant rickets (Orphanet:93160)
Idiopathic juvenile osteoporosis (Orphanet:85193)
Indolent systemic mastocytosis (Orphanet:98848)
Intellectual deficit, Buenos-Aires type (Orphanet:3079)
Intellectual deficit, X-linked - dysmorphism - cerebral atrophy (Orphanet:2958)
Isolated glycerol kinase deficiency (Orphanet:408)
Juvenile Paget disease (Orphanet:2801)
Kaler-Garrity-Stern syndrome (Orphanet:2324)
Kallmann syndrome (Orphanet:478)
Larsen-like osseous dysplasia - short stature (Orphanet:2370)
Lichstenstein syndrome (Orphanet:2390)
Linear verrucous nevus syndrome (Orphanet:2611)
Lipodystrophy due to peptidic growth factors deficiency (Orphanet:1979)
Lowry-MacLean syndrome (Orphanet:2409)
Marfan syndrome (Orphanet:558)
Marshall-Smith syndrome (Orphanet:561)
Mastocytosis (Orphanet:98292)
McCune-Albright syndrome (Orphanet:562)
Megalocornea-intellectual deficit syndrome (Orphanet:2479)
Menkes disease (Orphanet:565)
Metaphyseal chondrodysplasia, Spahr type (Orphanet:2501)
Metaphyseal dysplasia - maxillary hypoplasia - brachydacty (Orphanet:2504)
Microcephalic osteodysplastic primordial dwarfism types 1 and 3 (Orphanet:2636)
Mikati-Najjar-Sahli syndrome (Orphanet:2558)
Mu heavy-chain disease (Orphanet:100024)
Mucolipidosis type 3 (Orphanet:577)
Mucopolysaccharidosis type 4 (Orphanet:582)
Nasu-Hakola disease (Orphanet:2770)
Neu-Laxova syndrome (Orphanet:2671)
Occipital horn syndrome (Orphanet:198)
Oculocerebral hypopigmentation syndrome, Preus type (Orphanet:2720)
Oculocerebrorenal syndrome (Orphanet:534)
Oculocutaneous albinism type 1A (Orphanet:79431)
Orofaciodigital syndrome type 1 (Orphanet:2750)
Osteochondrodysplatic nanism - deafness - retinitis pigmentosa (Orphanet:2653)
Osteogenesis imperfecta (Orphanet:666)
Osteogenesis imperfecta type 4 (Orphanet:216820)
Osteopenia - myopia - hearing loss - intellectual deficit - facial dysmorphism (Orphanet:91133)
Osteopetrosis (Orphanet:2781)
Osteopetrosis with renal tubular acidosis (Orphanet:2785)
Osteoporosis - macrocephaly - blindness - joint hyperlaxity (Orphanet:2787)
Osteoporosis - pseudoglioma (Orphanet:2788)
Pachydermoperiostosis (Orphanet:2796)
Parastremmatic dwarfism (Orphanet:2646)
Partial androgen insensitivity syndrome (Orphanet:90797)
Pearson syndrome (Orphanet:699)
Perinatal lethal hypophosphatasia (Orphanet:247623)
Phakomatosis pigmentovascularis (Orphanet:2875)
Poland syndrome (Orphanet:2911)
Primary hyperoxaluria (Orphanet:416)
Primary intestinal lymphangiectasia (Orphanet:90362)
Primary pigmented nodular adrenocortical disease (Orphanet:189439)
Progressive familial intrahepatic cholestasis (Orphanet:172)
Prolidase deficiency (Orphanet:742)
Proximal tubulopathy - diabetes mellitus - cerebellar ataxia (Orphanet:3390)
Pseudoprogeria syndrome (Orphanet:2985)
Recessive dystrophic epidermolysis bullosa-generalized other (Orphanet:89842)
Rett syndrome (Orphanet:778)
Richards-Rundle syndrome (Orphanet:1399)
Richieri Costa-da Silva syndrome (Orphanet:3101)
Rothmund-Thomson syndrome (Orphanet:2909)
Rothmund-Thomson syndrome type 2 (Orphanet:221016)
SPONASTRIME dysplasia (Orphanet:93357)
Sakati-Nyhan syndrome (Orphanet:3128)
Schwartz-Jampel syndrome (Orphanet:800)
Segmental outgrowth - lipomatosis - arteriovenous malformation - epidermal nevus (Orphanet:137608)
Severe generalized recessive dystrophic epidermolysis bullosa (Orphanet:79408)
Short-limb skeletal dysplasia with severe combined immunodeficiency (Orphanet:935)
Shprintzen-Goldberg syndrome (Orphanet:2462)
Shwachman-Diamond syndrome (Orphanet:811)
Sialidosis type 2 (Orphanet:87876)
Spinocerebellar ataxia - dysmorphism (Orphanet:1185)
Spondylo-ocular syndrome (Orphanet:85194)
Spondyloepimetaphyseal dysplasia, Irapa type (Orphanet:93351)
Stickler syndrome (Orphanet:828)
Stüve-Wiedemann syndrome (Orphanet:3206)
Systemic mastocytosis (Orphanet:2467)
Telecanthus - hypertelorism - strabismus - pes cavus (Orphanet:3293)
Torg-Winchester syndrome (Orphanet:3460)
Trisomy 20p (Orphanet:261318)
Turner syndrome (Orphanet:881)
Urban-Rogers-Meyer syndrome (Orphanet:3409)
Werner syndrome (Orphanet:902)
Williams syndrome (Orphanet:904)
Wolcott-Rallison syndrome (Orphanet:1667)
Wolf-Hirschhorn syndrome (Orphanet:280)
X-linked hypophosphatemia (Orphanet:89936)