Mandibular prognathia

Symptom Information:

Symptom ID: HPO:0000303
Synonyms:
Enlarged mandible [HPO:0000303]
Large mandible [HPO:0000303]
Mandible prognathism [HPO:0000303]
Mandibular prognathism [HPO:0000303]
Prognathia [HPO:0000303]
Prognathism [HPO:0000303]
Prominent chin [HPO:0000303]
Prominent jaw [HPO:0000303]
Relative mandibular prognathism [HPO:0000303]
Prognathism [Orphanet:3640]
Congenital prognathism (disorder) [Orphanet:3640]
Enlarged mandible [OMIM:Enlarged mandible]
Large mandible [OMIM:Large mandible]
Mandible prognathism [OMIM:Mandible prognathism]
Mandibular prognathism [OMIM:Mandibular prognathism]
Prognathia [OMIM:Prognathia]
Prognathism [OMIM:Prognathism]
Prominent chin [OMIM:Prominent chin]
Prominent jaw [OMIM:Prominent jaw]
Relative mandibular prognathism [OMIM:Relative mandibular prognathism]
Prognathism/prognathia [Orphanet:3640]
Prognathism [MedDRA:10051481]
Maxillary prognathism [MedDRA:10051481]
Mandibular prognathism [MedDRA:10051481]
Prognathism (in some patients) [OMIM:Prognathism (in some patients)]
Prognathism (rare) [OMIM:Prognathism (rare)]
Quality:
Cross references:
Orphanet:3640 "Prognathism/prognathia" [Orphanet:3640]
OMIM: "Enlarged mandible" [OMIM:Enlarged mandible]
OMIM: "Large mandible" [OMIM:Large mandible]
OMIM: "Mandible prognathism" [OMIM:Mandible prognathism]
OMIM: "Mandibular prognathism" [OMIM:Mandibular prognathism]
OMIM: "Prognathia" [OMIM:Prognathia]
OMIM: "Prognathism" [OMIM:Prognathism]
OMIM: "Prominent chin" [OMIM:Prominent chin]
OMIM: "Prominent jaw" [OMIM:Prominent jaw]
OMIM: "Relative mandibular prognathism" [OMIM:Relative mandibular prognathism]
OMIM: "Prognathism (in some patients)" [OMIM:Prognathism (in some patients)]
OMIM: "Prognathism (rare)" [OMIM:Prognathism (rare)]
UMLS:C0033324 "Prognathism" [Orphanet:3640]
Is a (Direct Parents):
Orphanet Abnormal facial shape
HPO         Abnormality of the mandible
MedDRA Musculoskeletal and connective tissue deformities of skull, face and buccal cavity
HPO         Abnormality of the chin
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal axial skeleton morphology(HPO:0009121)
                Abnormality of the skull(HPO:0000929)
                   Abnormality of facial skeleton(HPO:0011821)
                      Abnormality of the mandible(HPO:0000277)
                         Mandibular prognathia(HPO:0000303)
       Abnormality of head or neck(HPO:0000152)
          Abnormality of the head(HPO:0000234)
             Abnormality of the skull(HPO:0000929)
                Abnormality of facial skeleton(HPO:0011821)
                   Abnormality of the mandible(HPO:0000277)
                      Mandibular prognathia(HPO:0000303)
             Abnormality of the face(HPO:0000271)
                Abnormality of the chin(HPO:0000306)
                   Mandibular prognathia(HPO:0000303)
MedDRA:
Musculoskeletal and connective tissue disorders(MedDRA:10028395)
    Musculoskeletal and connective tissue deformities (incl intervertebral disc disorders)(MedDRA:10028377)
       Musculoskeletal and connective tissue deformities of skull, face and buccal cavity(MedDRA:10028378)
          Mandibular prognathia(HPO:0000303)
Database Frequency: 179 / 7739
Resource:

All diseases associated with this symptom:

14q12 microdeletion syndrome (Orphanet:261144)
17p11.2 microduplication syndrome (Orphanet:1713)
17q12 microdeletion syndrome (Orphanet:261265)
3M syndrome (Orphanet:2616)
ACRODYSOSTOSIS 1 WITH OR WITHOUT HORMONE RESISTANCE (OMIM:101800)
ACROMEGALOID CHANGES, CUTIS VERTICIS GYRATA, AND CORNEAL LEUKOMA (OMIM:102100)
AREDYLD syndrome (Orphanet:1133)
AXENFELD-RIEGER SYNDROME, TYPE 2 (OMIM:601499)
Achalasia - microcephaly (Orphanet:929)
Acro-fronto-facio-nasal dysostosis (Orphanet:1784)
Acrodysostosis (Orphanet:950)
Acrodysostosis with multiple hormone resistance (Orphanet:280651)
Acromegaly (Orphanet:963)
Adenylosuccinate lyase deficiency (Orphanet:46)
Alpha-mannosidosis (Orphanet:61)
Aminopterin/methotrexate embryofetopathy (Orphanet:1908)
Angelman syndrome (Orphanet:72)
Anophthalmia - megalocornea - cardiopathy - skeletal anomalies (Orphanet:1101)
Aortic arch anomaly - peculiar facies - intellectual deficit (Orphanet:1110)
Apert syndrome (Orphanet:87)
Aspartylglucosaminuria (Orphanet:93)
Autosomal dominant osteosclerosis, Worth type (Orphanet:2790)
Autosomal dominant prognathism (Orphanet:2964)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
Barber-Say syndrome (Orphanet:1231)
Barth syndrome (Orphanet:111)
Beckwith-Wiedemann syndrome due to 11p15 microdeletion (Orphanet:231127)
Beckwith-Wiedemann syndrome due to 11p15 microduplication (Orphanet:96076)
Berardinelli-Seip congenital lipodystrophy (Orphanet:528)
Blepharophimosis - ptosis - esotropia - syndactyly - short stature (Orphanet:2057)
Blepharophimosis - radioulnar synostosis (Orphanet:1256)
Brachyolmia-amelogenesis imperfecta syndrome (Orphanet:2899)
Branchio-skeleto-genital syndrome (Orphanet:1299)
CATARACTS, CONGENITAL, WITH SENSORINEURAL DEAFNESS, DOWN SYNDROME-LIKEFACIAL APPEARANCE, SHORT STATURE, AND MENTAL RETARDATION (OMIM:601088)
COCKAYNE SYNDROME A (OMIM:216400)
COCKAYNE SYNDROME B (OMIM:133540)
COCKAYNE SYNDROME, TYPE III (OMIM:216411)
CRANIOMETADIAPHYSEAL DYSPLASIA (OMIM:269300)
CRANIOMETAPHYSEAL DYSPLASIA, AUTOSOMAL DOMINANT (OMIM:123000)
CRANIOMETAPHYSEAL DYSPLASIA, AUTOSOMAL RECESSIVE (OMIM:218400)
Camptodactyly syndrome, Guadalajara type 1 (Orphanet:1327)
Camurati-Engelmann disease (Orphanet:1328)
Choanal atresia - deafness - cardiac defects - dysmorphism (Orphanet:1200)
Christianson syndrome (Orphanet:85278)
Cockayne syndrome (Orphanet:191)
Coffin-Lowry syndrome (Orphanet:192)
Craniometadiaphyseal dysplasia, wormian bone type (Orphanet:85184)
Craniometaphyseal dysplasia (Orphanet:1522)
Crouzon disease (Orphanet:207)
DYGGVE-MELCHIOR-CLAUSEN DISEASE (OMIM:223800)
DYGGVE-MELCHIOR-CLAUSEN SYNDROME, X-LINKED (OMIM:304950)
Dental ankylosis (Orphanet:1077)
Dermato-cardio-skeletal syndrome, Borrone type (Orphanet:1266)
Dermo-odonto dysplasia (Orphanet:1660)
Developmental delay with autism spectrum disorder and gait instability (Orphanet:329195)
Distal 22q11.2 microduplication syndrome (Orphanet:261337)
Dyggve-Melchior-Clausen disease (Orphanet:239)
Epidermolysis bullosa simplex with anodontia/hypodontia (Orphanet:2325)
Fabry disease (Orphanet:324)
Facial dysmorphism - shawl scrotum - joint laxity (Orphanet:1778)
Familial osteodysplasia, Anderson type (Orphanet:2769)
Familial scaphocephaly syndrome, McGillivray type (Orphanet:168624)
Fragile X syndrome (Orphanet:908)
Freeman-Sheldon syndrome (Orphanet:2053)
GAPO syndrome (Orphanet:2067)
GM1 gangliosidosis (Orphanet:354)
Geroderma osteodysplastica (Orphanet:2078)
Glomerulonephritis - sparse hair - telangiectasis (Orphanet:2087)
Gorlin syndrome (Orphanet:377)
HYPERPHOSPHATASIA WITH MENTAL RETARDATION SYNDROME 1 (OMIM:239300)
Hydrocephalus - costovertebral dysplasia - Sprengel anomaly (Orphanet:2180)
Hyperostosis corticalis generalisata (Orphanet:3416)
Hyperphosphatasia-intellectual deficiency syndrome (Orphanet:247262)
Hypospadias - hypertelorism - coloboma and deafness (Orphanet:157788)
Intellectual deficit - athetosis - microphthalmia (Orphanet:1236)
Intellectual deficit - dysmorphism - hypogonadism - diabetes mellitus (Orphanet:3044)
Intellectual deficit - polydactyly - uncombable hair (Orphanet:3082)
Intellectual deficit, Buenos-Aires type (Orphanet:3079)
Intellectual deficit, X-linked - Dandy-Walker malformation - basal ganglia disease - Seizures (Orphanet:1568)
Intellectual deficit, X-linked - hypogammaglobulinemia - progressive neurological deterioration (Orphanet:85317)
Intellectual deficit, X-linked - seizures - psoriasis (Orphanet:3052)
Intellectual deficit, X-linked, Armfield type (Orphanet:85276)
Intellectual deficit, X-linked, Snyder type (Orphanet:3063)
Intellectual deficit, X-linked, Wilson type (Orphanet:85290)
Jackson-Weiss syndrome (Orphanet:1540)
Kaler-Garrity-Stern syndrome (Orphanet:2324)
Kleefstra syndrome (Orphanet:261494)
LEOPARD SYNDROME 1 (OMIM:151100)
LEOPARD SYNDROME 2 (OMIM:611554)
LIPODYSTROPHY, CONGENITAL GENERALIZED, TYPE 1 (OMIM:608594)
LIPODYSTROPHY, CONGENITAL GENERALIZED, TYPE 2 (OMIM:269700)
Late-onset localized junctional epidermolysis bullosa - intellectual deficit (Orphanet:231556)
Lenz-Majewski hyperostotic dwarfism (Orphanet:2658)
Lethal osteosclerotic bone dysplasia (Orphanet:1832)
MACROCEPHALY/MEGALENCEPHALY SYNDROME, AUTOSOMAL RECESSIVE (OMIM:248000)
MARFANOID HABITUS WITH SITUS INVERSUS (OMIM:609008)
MAXILLOFACIAL DYSOSTOSIS (OMIM:155000)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 24 (OMIM:615828)
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 41 (OMIM:615637)
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 48 (OMIM:616269)
MENTAL RETARDATION, OBESITY, MANDIBULAR PROGNATHISM, AND EYE AND SKINANOMALIES (OMIM:606772)
MENTAL RETARDATION, X-LINKED 21 (OMIM:300143)
MENTAL RETARDATION, X-LINKED, SYNDROMIC 14 (OMIM:300676)
MENTAL RETARDATION, X-LINKED, SYNDROMIC, CHUDLEY-SCHWARTZ TYPE (OMIM:300861)
MMEP syndrome (Orphanet:3434)
MUCOLIPIDOSIS III ALPHA/BETA (OMIM:252600)
MYASTHENIC SYNDROME, CONGENITAL, 4C, ASSOCIATED WITH ACETYLCHOLINERECEPTOR DEFICIENCY (OMIM:608931)
Macrocephaly - spastic paraplegia - dysmorphism (Orphanet:2429)
Maxillo-nasal dysplasia (Orphanet:1248)
McCune-Albright syndrome (Orphanet:562)
McDonough syndrome (Orphanet:2471)
Microbrachycephaly - ptosis - cleft lip (Orphanet:2511)
Microcephaly - cleft palate (Orphanet:2521)
Microcephaly - glomerulonephritis - marfanoid habitus (Orphanet:2172)
Microcephaly - lymphedema - chorioretinopathy (Orphanet:2526)
Monosomy 18q (Orphanet:1600)
Mowat-Wilson syndrome (Orphanet:2152)
Mucolipidosis type 3 (Orphanet:577)
Mucopolysaccharidosis type 2 (Orphanet:580)
Mucopolysaccharidosis type 2, attenuated form (Orphanet:217093)
Mucopolysaccharidosis type 2, severe form (Orphanet:217085)
Mucopolysaccharidosis type 4A (Orphanet:309297)
Mucopolysaccharidosis type 4B (Orphanet:309310)
Myhre syndrome (Orphanet:2588)
Nance-Horan syndrome (Orphanet:627)
Neurofaciodigitorenal syndrome (Orphanet:2673)
Noonan syndrome with multiple lentigines (Orphanet:500)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 2 (OMIM:259710)
Oculo-reno-cerebellar syndrome (Orphanet:2715)
Oculocerebrorenal syndrome (Orphanet:534)
Oculodentodigital dysplasia (Orphanet:2710)
Oculoosteocutaneous syndrome (Orphanet:2713)
Odonto-tricho-ungual-digito-palmar syndrome (Orphanet:69082)
Oro-mandibular-limb hypogenesis syndrome (Orphanet:2749)
Osteoglophonic dwarfism (Orphanet:2645)
Osteopetrosis (Orphanet:2781)
Osteopetrosis with renal tubular acidosis (Orphanet:2785)
PERMANENT MOLARS, SECONDARY RETENTION OF (OMIM:157950)
Pfeiffer syndrome (Orphanet:710)
Pitt-Hopkins-like syndrome 2 (OMIM:614325)
Postaxial polydactyly - dental and vertebral anomalies (Orphanet:2916)
Progeroid syndrome, Petty type (Orphanet:2963)
Proteus-like syndrome (Orphanet:2969)
Pyle disease (Orphanet:3005)
Rabson-Mendenhall syndrome (Orphanet:769)
Radial hypoplasia - triphalangeal thumbs - hypospadias - maxillary diastema (Orphanet:2252)
Renal cysts and diabetes syndrome (Orphanet:93111)
Renpenning syndrome (Orphanet:3242)
Rhizomelic dysplasia, Patterson-Lowry type (Orphanet:2831)
Rothmund-Thomson syndrome (Orphanet:2909)
SCLEROSTEOSIS 1 (OMIM:269500)
SCLEROSTEOSIS 2 (OMIM:614305)
SOTOS SYNDROME 1 (OMIM:117550)
Sakati-Nyhan syndrome (Orphanet:3128)
Scalp-ear-nipple syndrome (Orphanet:2036)
Scheie syndrome (Orphanet:93474)
Sclerosteosis (Orphanet:3152)
Severe intellectual deficit - epilepsy - anal anomalies - distal phalangeal hypoplasia (Orphanet:94066)
Severe intellectual deficit and progressive spastic paraplegia (Orphanet:280763)
Sheldon-Hall syndrome (Orphanet:1147)
Short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome (Orphanet:314394)
Simpson-Golabi-Behmel syndrome (Orphanet:373)
Skeletal dysplasia - epilepsy - short stature (Orphanet:1858)
Smith-Magenis syndrome (Orphanet:819)
Sotos syndrome (Orphanet:821)
Spondyloepimetaphyseal dysplasia, aggrecan type (Orphanet:171866)
Syndromic X-linked intellectual deficit due to JARID1C mutation (Orphanet:85279)
TENORIO SYNDROME (OMIM:616260)
Trismus - pseudocamptodactyly (Orphanet:3377)
VAN BUCHEM DISEASE, TYPE 2 (OMIM:607636)
W syndrome (Orphanet:2804)
Waardenburg syndrome (Orphanet:3440)
Waardenburg syndrome type 1 (Orphanet:894)
Waardenburg syndrome type 3 (Orphanet:896)
Weaver syndrome (Orphanet:3447)
Wilson-Turner syndrome (Orphanet:3459)
X-linked creatine transporter deficiency (Orphanet:52503)
X-linked intellectual deficit - cerebellar hypoplasia (Orphanet:137831)
X-linked intellectual deficit with marfanoid habitus (Orphanet:776)