Neutropenia

Symptom Information:

Symptom ID: HPO:0001875
Synonyms:
Peripheral neutropenia [HPO:0001875]
Neutropenic disorder (disorder) [Orphanet:48480]
Neutropenia (finding) [Orphanet:48480]
Neutropenia [Orphanet:48480]
Neutrophil count decreased [Orphanet:48480]
Neutropenia [OMIM:Neutropenia]
Peripheral neutropenia [OMIM:Peripheral neutropenia]
Polynuclear cells/neutrophils anomalies/neutropenia [Orphanet:48480]
Neutrophil count decreased [MedDRA:10029366]
Blood neutrophil count decreased [MedDRA:10029366]
Neutrophil count low [MedDRA:10029366]
Neutrophils reduced [MedDRA:10029366]
Plasma neutrophil count decreased [MedDRA:10029366]
Serum neutrophil count decreased [MedDRA:10029366]
Segmented cell decreased [MedDRA:10029366]
Absolute neutrophil count decreased [MedDRA:10029366]
Segmented neutrophil count decreased [MedDRA:10029366]
Neutropenia [MedDRA:10029354]
Neutropenia aggravated [MedDRA:10029354]
Chronic neutropenia [MedDRA:10029354]
Chronic neutropenia [OMIM:Chronic neutropenia]
Neutropenia (in 1 patient) [OMIM:Neutropenia (in 1 patient)]
Neutropenia (in some patients) [OMIM:Neutropenia (in some patients)]
Neutropenias [MedDRA:10029355]
Quality:
Cross references:
Orphanet:48480 "Polynuclear cells/neutrophils anomalies/neutropenia" [Orphanet:48480]
OMIM: "Neutropenia" [OMIM:Neutropenia]
OMIM: "Peripheral neutropenia" [OMIM:Peripheral neutropenia]
OMIM: "Chronic neutropenia" [OMIM:Chronic neutropenia]
OMIM: "Neutropenia (in 1 patient)" [OMIM:Neutropenia (in 1 patient)]
OMIM: "Neutropenia (in some patients)" [OMIM:Neutropenia (in some patients)]
UMLS:C0027947 "Neutropenia" [HPO:0001875]
UMLS:C0027947 "Neutropenia" [Orphanet:48480]
UMLS:C0853697 "Neutrophil count decreased" [Orphanet:48480]
Is a (Direct Parents):
Orphanet Abnormality of neutrophils
MedDRA Abnormality of leukocytes
MedDRA White blood cell analyses
Orphanet Abnormality of leukocytes
HPO         Abnormal neutrophil cell number
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of cellular immune system(HPO:0010987)
             Abnormality of leukocytes(HPO:0001881)
                Abnormality of myeloid leukocytes(HPO:0010974)
                   Abnormality of granulocytes(HPO:0001911)
                      Abnormality of neutrophils(HPO:0001874)
                         Abnormal neutrophil cell number(HPO:0011991)
                            Neutropenia(HPO:0001875)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of leukocytes(HPO:0001881)
             Abnormality of myeloid leukocytes(HPO:0010974)
                Abnormality of granulocytes(HPO:0001911)
                   Abnormality of neutrophils(HPO:0001874)
                      Abnormal neutrophil cell number(HPO:0011991)
                         Neutropenia(HPO:0001875)
MedDRA:
Blood and lymphatic system disorders(MedDRA:10005329)
    Abnormality of leukocytes(HPO:0001881)
       Neutropenia(HPO:0001875)
Investigations(MedDRA:10022891)
    Haematology investigations (incl blood groups)(MedDRA:10018851)
       White blood cell analyses(MedDRA:10047938)
          Neutropenia(HPO:0001875)
Database Frequency: 83 / 7739
Resource:

All diseases associated with this symptom:

3-@METHYLGLUTACONIC ACIDURIA WITH CATARACTS, NEUROLOGIC INVOLVEMENT,AND NEUTROPENIA (OMIM:616271)
AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE (OMIM:601495)
AGAMMAGLOBULINEMIA 3, AUTOSOMAL RECESSIVE (OMIM:613501)
AGAMMAGLOBULINEMIA 4, AUTOSOMAL RECESSIVE (OMIM:613502)
AGAMMAGLOBULINEMIA 7, AUTOSOMAL RECESSIVE (OMIM:615214)
Adult idiopathic neutropenia (Orphanet:2688)
Aspartylglucosaminuria (Orphanet:93)
Autosomal agammaglobulinemia (Orphanet:33110)
Autosomal dominant severe congenital neutropenia (Orphanet:486)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
Barth syndrome (Orphanet:111)
Blackfan-Diamond anemia (Orphanet:124)
COMBINED INFLAMMATORY AND IMMUNOLOGIC DEFECT (OMIM:216920)
Cartilage-hair hypoplasia (Orphanet:175)
Cohen syndrome (Orphanet:193)
Combined immunodeficiency due to STK4 deficiency (Orphanet:314689)
DIAMOND-BLACKFAN ANEMIA 11 (OMIM:614900)
DK1-CDG (Orphanet:91131)
ENCEPHALOMYOPATHY, MITOCHONDRIAL, DUE TO VOLTAGE-DEPENDENT ANION CHANNELDEFICIENCY (OMIM:614520)
ENTEROPATHY, FAMILIAL, WITH VILLOUS EDEMA AND IMMUNOGLOBULIN G2 DEFICIENCY (OMIM:600351)
FANCONI ANEMIA, COMPLEMENTATION GROUP A (OMIM:227650)
FANCONI ANEMIA, COMPLEMENTATION GROUP C (OMIM:227645)
FANCONI ANEMIA, COMPLEMENTATION GROUP D2 (OMIM:227646)
FANCONI ANEMIA, COMPLEMENTATION GROUP E (OMIM:600901)
FANCONI ANEMIA, COMPLEMENTATION GROUP G (OMIM:614082)
Familial isolated dilated cardiomyopathy (Orphanet:154)
Fanconi anemia (Orphanet:84)
Felty syndrome (Orphanet:47612)
Glutathione synthetase deficiency with 5-oxoprolinuria (Orphanet:289846)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 4 (OMIM:603552)
Hereditary folate malabsorption (Orphanet:90045)
Hermansky-Pudlak syndrome (Orphanet:79430)
Hermansky-Pudlak syndrome with neutropenia (Orphanet:183678)
Hyper-IgM syndrome type 3 (Orphanet:101090)
IMMUNODEFICIENCY 23 (OMIM:615816)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
Immunodeficiency by defective expression of HLA class 2 (Orphanet:572)
Kostmann syndrome (Orphanet:99749)
LAZY LEUKOCYTE SYNDROME (OMIM:150550)
LEUKOENCEPHALOPATHY, ARTHRITIS, COLITIS, AND HYPOGAMMAGLOBULINEMA (OMIM:608809)
Letterer-Siwe disease (Orphanet:99870)
Lichstenstein syndrome (Orphanet:2390)
MYELODYSPLASIA, IMMUNODEFICIENCY, FACIAL DYSMORPHISM, SHORT STATURE,AND PSYCHOMOTOR DELAY (OMIM:601347)
Methylmalonic acidemia with homocystinuria (Orphanet:26)
Methylmalonic acidemia with homocystinuria, type cblC (Orphanet:79282)
Methylmalonic acidemia with homocystinuria, type cblF (Orphanet:79284)
Methylmalonic acidemia with homocystinuria, type cblJ (Orphanet:369955)
Microcephalic primordial dwarfism, Toriello type (Orphanet:2643)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with variable craniofacial anomalies (Orphanet:369897)
Monocytopenia with susceptibility to infections (Orphanet:228423)
Myopathy, lactic acidosis, and sideroblastic anemia 2; MLASA2 (OMIM:613561)
NEUTROPENIA, CHRONIC FAMILIAL (OMIM:162700)
NEUTROPENIA, SEVERE CONGENITAL, 6, AUTOSOMAL RECESSIVE (OMIM:616022)
ONYCHOTRICHODYSPLASIA AND NEUTROPENIA (OMIM:258360)
PELGER-HUET ANOMALY (OMIM:169400)
Pearson syndrome (Orphanet:699)
Poikiloderma with neutropenia (Orphanet:221046)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Primary immunodeficiency syndrome due to p14 deficiency (Orphanet:90023)
Propionic acidemia (Orphanet:35)
RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER (OMIM:614470)
RETINAL VENOUS BEADING (OMIM:180080)
Recurrent infections-myelofibrosis-nephromegaly syndrome (Orphanet:369852)
SLC35A1-CDG (Orphanet:238459)
Schimke immuno-osseous dysplasia (Orphanet:1830)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Shwachman-Diamond syndrome (Orphanet:811)
THROMBOCYTOPENIA 5 (OMIM:616216)
THROMBOCYTOPENIA, CYCLIC (OMIM:188020)
TRIMETHYLAMINURIA (OMIM:602079)
Transaldolase deficiency (Orphanet:101028)
Transcobalamin deficiency (Orphanet:859)
Vitamin B12-responsive methylmalonic acidemia (Orphanet:28)
Vitamin B12-responsive methylmalonic acidemia type cblA (Orphanet:79310)
Vitamin B12-responsive methylmalonic acidemia type cblB (Orphanet:79311)
WHIM syndrome (Orphanet:51636)
Wolcott-Rallison syndrome (Orphanet:1667)
Wolfram syndrome, mitochondrial form (OMIM:598500)
X-linked dyserythropoetic anemia with abnormal platelets and neutropenia (Orphanet:363727)
X-linked hyper-IgM syndrome (Orphanet:101088)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)
[DEL] NEUTROPENIA, SEVERE CONGENITAL, 4, AUTOSOMAL RECESSIVE; SCN4 (OMIM:612541)