Symptom Information:

Symptom ID: HPO:0001396
Occlusion of bile duct (disorder) [Orphanet:29180]
Cholestasis (finding) [Orphanet:29180]
Cholestatic liver disease [Orphanet:29180]
Cholestasis [Orphanet:29180]
Cholestatic hepatic disorder [Orphanet:29180]
Cholestasis [OMIM:Cholestasis]
Hepatitis/icterus/cholestasis [Orphanet:29180]
Bile duct obstruction [Orphanet:29180]
Bile duct obstruction [MedDRA:10056375]
Bile duct obstruction (excl calculus) [MedDRA:10056375]
Bile duct obstruction due to calculus [MedDRA:10056375]
Bile duct obstruction NOS [MedDRA:10056375]
Calculus of bile duct without mention of cholecystitis, with obstruction [MedDRA:10056375]
Extrahepatic biliary obstruction [MedDRA:10056375]
Intrahepatic biliary obstruction [MedDRA:10056375]
Obstruction of bile duct [MedDRA:10056375]
Obstruction of cystic duct [MedDRA:10056375]
Mirizzi syndrome [MedDRA:10056375]
Cholestasis [MedDRA:10008635]
Biliary stasis [MedDRA:10008635]
Cholestasis extrahepatic [MedDRA:10008635]
Cholestasis intrahepatic [MedDRA:10008635]
Cholestatic liver disease [MedDRA:10008635]
Liver cholestasis [MedDRA:10008635]
Pure intrahepatic cholestasis [MedDRA:10008635]
Cholestatic hepatic disorder [MedDRA:10008635]
Anicteric cholestasis [MedDRA:10008635]
Cholestasis (1 patient) [OMIM:Cholestasis (1 patient)]
Cholestasis (9%) [OMIM:Cholestasis (9%)]
Cholestasis (less common) [OMIM:Cholestasis (less common)]
Intrahepatic biliary obstruction [MedDRA:10022793]
Intrahepatic biliary tract obstruction [Orphanet:28220]
Intrahepatic biliary obstruction [Orphanet:28220]
Intrahepatic biliary tract atresia/obstruction [Orphanet:28220]
Hepatitis [MedDRA:10019717]
Inflammatory disease of liver (disorder) [Orphanet:29180]
Hepatitis [Orphanet:29180]
Extrahepatic biliary obstruction [MedDRA:10015819]
Extrahepatic biliary tract obstruction [Orphanet:28330]
Extrahepatic cholestasis (finding) [Orphanet:28330]
Extrahepatic obstructive biliary disease (disorder) [Orphanet:28330]
Cholestasis, Extrahepatic [Orphanet:28330]
Extrahepatic biliary tract atresia/obstruction [Orphanet:28330]
Cross references:
HPO:0002611 "Cholestatic liver disease" [Orphanet:29180]
Orphanet:29180 "Hepatitis/icterus/cholestasis" [Orphanet:29180]
Orphanet:28220 "Intrahepatic biliary tract atresia/obstruction" [Orphanet:28220]
Orphanet:28330 "Extrahepatic biliary tract atresia/obstruction" [Orphanet:28330]
OMIM: "Cholestasis" [OMIM:Cholestasis]
OMIM: "Cholestasis (1 patient)" [OMIM:Cholestasis (1 patient)]
OMIM: "Cholestasis (9%)" [OMIM:Cholestasis (9%)]
OMIM: "Cholestasis (less common)" [OMIM:Cholestasis (less common)]
UMLS:C0008370 "Cholestasis" [HPO:0001396]
UMLS:C0860204 "Cholestatic liver disease" [Orphanet:29180]
UMLS:C0008370 "Cholestasis" [Orphanet:29180]
UMLS:C0920027 "Cholestatic hepatic disorder" [Orphanet:29180]
UMLS:C0860211 "Intrahepatic biliary obstruction" [Orphanet:28220]
UMLS:C0019158 "Hepatitis" [Orphanet:29180]
UMLS:C0005398 "Cholestasis, Extrahepatic" [Orphanet:28330]
Is a (Direct Parents):
Orphanet Jaundice
MedDRA Obstructive bile duct disorders (excl neoplasms)
Orphanet Biliary tract abnormality
Orphanet Decreased liver function
HPO         Abnormality of the biliary system
MedDRA Cholestasis and jaundice
Is a (Whole tree): HPO:
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the abdomen(HPO:0001438)
          Abnormality of the abdominal organs(HPO:0002012)
             Abnormality of the liver(HPO:0001392)
                Abnormality of the biliary system(HPO:0004297)
Hepatobiliary disorders(MedDRA:10019805)
    Bile duct disorders(MedDRA:10004606)
       Obstructive bile duct disorders (excl neoplasms)(MedDRA:10029976)
    Hepatic and hepatobiliary disorders(MedDRA:10019654)
       Cholestasis and jaundice(MedDRA:10008636)
Database Frequency: 136 / 7739

All diseases associated with this symptom:

Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins (Orphanet:217371)
Adult Still's disease (Orphanet:829)
Alagille syndrome (Orphanet:52)
Alagille syndrome due to 20p12 microdeletion (Orphanet:261600)
Alagille syndrome due to a JAG1 point mutation (Orphanet:261619)
Alagille syndrome due to a NOTCH2 point mutation (Orphanet:261629)
Alpha-1-antitrypsin deficiency (Orphanet:60)
Alpha-thalassemia (Orphanet:846)
Alveolar echinococcosis (Orphanet:284)
Apolipoprotein A-I deficiency (Orphanet:425)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Autoimmune hemolytic anemia (Orphanet:98375)
Autoimmune hemolytic anemia, warm type (Orphanet:90033)
Autosomal agammaglobulinemia (Orphanet:33110)
Autosomal dominant beta2-microglobulinic amyloidosis (Orphanet:314652)
Babesiosis (Orphanet:108)
Benign recurrent intrahepatic cholestasis (Orphanet:65682)
Beta-thalassemia (Orphanet:848)
Beta-thalassemia major (Orphanet:231214)
Bifunctional enzyme deficiency (Orphanet:300)
Budd-Chiari syndrome (Orphanet:131)
Carcinoma of the gallbladder (Orphanet:56044)
Carney triad (Orphanet:139411)
Central congenital hypothyroidism (Orphanet:226298)
Cerebrotendinous xanthomatosis (Orphanet:909)
Cholangiocarcinoma (Orphanet:70567)
Cholestasis - lymphedema (Orphanet:1414)
Cholestasis - pigmentary retinopathy - cleft palate (Orphanet:1415)
Cholesteryl ester storage disease (Orphanet:75234)
Choreoacanthocytosis (Orphanet:2388)
Chronic mucocutaneous candidiasis (Orphanet:1334)
Ch├ędiak-Higashi syndrome (Orphanet:167)
Classic galactosemia (Orphanet:79239)
Congenital bile acid synthesis defect type 1 (Orphanet:79301)
Congenital bile acid synthesis defect type 2 (Orphanet:79303)
Congenital bile acid synthesis defect type 3 (Orphanet:79302)
Congenital bile acid synthesis defect type 4 (Orphanet:79095)
Congenital hypothyroidism (Orphanet:442)
Congenital hypothyroidism due to developmental anomaly (Orphanet:95711)
Congenital hypothyroidism due to transplacental passage of maternal TSH-binding inhibitory antibodies (Orphanet:95715)
Congenital rubella syndrome (Orphanet:290)
Congenital toxoplasmosis (Orphanet:858)
Crigler-Najjar syndrome (Orphanet:205)
Crigler-Najjar syndrome type 1 (Orphanet:79234)
Crigler-Najjar syndrome type 2 (Orphanet:79235)
Crimean-Congo hemorrhagic fever (Orphanet:99827)
Cryoglobulinemic vasculitis (Orphanet:91138)
Disorder of bile acid synthesis (Orphanet:79168)
Distomatosis (Orphanet:1685)
Dominant beta-thalassemia (Orphanet:231226)
Drug rash with eosinophilia and systemic symptoms (Orphanet:139402)
Drug-induced autoimmune hemolytic anemia (Orphanet:90037)
Dubin-Johnson syndrome (Orphanet:234)
Familial renal amyloidosis (Orphanet:85450)
Familial thyroid dyshormonogenesis (Orphanet:95716)
Fumaric aciduria (Orphanet:24)
GRACILE syndrome (Orphanet:53693)
Galactose epimerase deficiency (Orphanet:79238)
Galactosemia (Orphanet:352)
Gastrointestinal stromal tumor (Orphanet:44890)
Gaucher disease (Orphanet:355)
Gaucher disease type 1 (Orphanet:77259)
Gaucher disease type 2 (Orphanet:77260)
Glycogen storage disease due to glycogen branching enzyme deficiency (Orphanet:367)
Griscelli disease (Orphanet:381)
Griscelli disease type 2 (Orphanet:79477)
Hashimoto-Pritzker syndrome (Orphanet:99872)
Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 (Orphanet:137681)
Hydatidosis (Orphanet:400)
Hyperbiliverdinemia (Orphanet:276405)
Hypermethioninemia encephalopathy due to adenosine kinase deficiency (Orphanet:289290)
Hypothyroidism due to TSH receptor mutations (Orphanet:90673)
Hypothyroidism due to deficient transcription factors involved in pituitary development or function (Orphanet:226307)
Ichthyosis - hypotrichosis - sclerosing cholangitis (Orphanet:59303)
Idiopathic congenital hypothyroidism (Orphanet:95717)
Isolated CoQ-cytochrome C reductase deficiency (Orphanet:1460)
Isolated polycystic liver disease (Orphanet:2924)
Isolated sedoheptulokinase deficiency (ORPHA:440713)
Isolated thyroid-stimulating hormone deficiency (Orphanet:90674)
Jeune syndrome (Orphanet:474)
Johanson-Blizzard syndrome (Orphanet:2315)
Kawasaki disease (Orphanet:2331)
Klatskin tumor (Orphanet:99978)
Lambert syndrome (Orphanet:1296)
Lathosterolosis (Orphanet:46059)
Legionellosis (Orphanet:549)
Leprechaunism (Orphanet:508)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
Lichen planopilaris (Orphanet:525)
MEDNIK syndrome (Orphanet:171851)
Menkes disease (Orphanet:565)
Mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency (Orphanet:279934)
Mitochondrial trifunctional protein deficiency (Orphanet:746)
Mixed-type autoimmune hemolytic anemia (Orphanet:90036)
Mucopolysaccharidosis type 7 (Orphanet:584)
Muscular pseudohypertrophy - hypothyroidism (Orphanet:2349)
Navajo neurohepatopathy (Orphanet:255229)
Neonatal diabetes - congenital hypothyroidism - congenital glaucoma - hepatic fibrosis - polycystic kidneys (Orphanet:79118)
Neonatal hemochromatosis (Orphanet:446)
Nephronophthisis 16 (OMIM:615382)
Nephronophthisis 18 (OMIM:615862)
Nephronophthisis 19 (OMIM:616217)
Nephronophthisis 9 (OMIM:613824)
Niemann-Pick disease type C (Orphanet:646)
Obesity due to pro-opiomelanocortin deficiency (Orphanet:71526)
Occipital horn syndrome (Orphanet:198)
Pearson syndrome (Orphanet:699)
Peripheral hypothyroidism (Orphanet:226310)
Peripheral resistance to thyroid hormones (Orphanet:97927)
Permanent congenital hypothyroidism (Orphanet:226292)
Polyarteritis nodosa (Orphanet:767)
Primary congenital hypothyroidism (Orphanet:226295)
Primary congenital hypothyroidism without thyroid developmental anomaly (Orphanet:95714)
Progressive familial intrahepatic cholestasis (Orphanet:172)
Relapsing polychondritis (Orphanet:728)
Renal cysts and diabetes syndrome (Orphanet:93111)
Renal tubulopathy - encephalopathy - liver failure (Orphanet:254902)
Renal-hepatic-pancreatic dysplasia (Orphanet:294415)
Resistance to thyrotropin-releasing hormone syndrome (Orphanet:99832)
Reynolds syndrome (Orphanet:779)
Rift valley fever (Orphanet:319251)
Rotor syndrome (Orphanet:3111)
Saldino-Mainzer syndrome (Orphanet:140969)
Senior-Loken syndrome 9 (OMIM:616629)
Short-rib thoracic dysplasia 10 with or without polydactyly (OMIM:615630)
Syndromic diarrhea (Orphanet:84064)
Thyroid ectopia (Orphanet:95712)
Thyroid hemiagenesis (Orphanet:95719)
Thyroid hypoplasia (Orphanet:95720)
Transient congenital hypothyroidism (Orphanet:178045)
Wolcott-Rallison syndrome (Orphanet:1667)
Wolman disease (Orphanet:75233)
X-linked agammaglobulinemia (Orphanet:47)
Yellow fever (Orphanet:99829)
Zellweger syndrome (Orphanet:912)