Joint laxity

Symptom Information:

Symptom ID: HPO:0001388
Synonyms:
Lax joints [HPO:0001388]
Loose-jointedness [HPO:0001388]
Loosejointedness [HPO:0001388]
Joint hypermobility [Orphanet:46360]
Joint laxity (finding) [Orphanet:46360]
Range of joint movement increased (finding) [Orphanet:46360]
Hypermobility, Joint [Orphanet:46360]
Joint laxity [OMIM:Joint laxity]
Lax joints [OMIM:Lax joints]
Loose-jointedness [OMIM:Loose-jointedness]
Loosejointedness [OMIM:Loosejointedness]
Hyperextensible joints/articular hyperlaxity [Orphanet:46360]
Joint laxity [Orphanet:46360]
Joint laxity [MedDRA:10070874]
Joint hypermobility (in some patients) [OMIM:Joint hypermobility (in some patients)]
Joint hypermobility (large and small joints) [OMIM:Joint hypermobility (large and small joints)]
Joint hypermobility (rare) [OMIM:Joint hypermobility (rare)]
Joint laxity (elbow) [OMIM:Joint laxity (elbow)]
Joint laxity (elbow, wrist, fingers) [OMIM:Joint laxity (elbow, wrist, fingers)]
Joint laxity (except elbow) [OMIM:Joint laxity (except elbow)]
Joint laxity (fingers and wrist) [OMIM:Joint laxity (fingers and wrist)]
Joint laxity (hands and feet) [OMIM:Joint laxity (hands and feet)]
Joint laxity (hip, knee, shoulder, wrist, fingers) [OMIM:Joint laxity (hip, knee, shoulder, wrist, fingers)]
Quality:
Cross references:
HPO:0001382 "Joint hypermobility" [Orphanet:46360]
HPO:0005692 "Joint hyperflexibility" [Orphanet:46360]
Orphanet:46360 "Hyperextensible joints/articular hyperlaxity" [Orphanet:46360]
OMIM: "Joint laxity" [OMIM:Joint laxity]
OMIM: "Lax joints" [OMIM:Lax joints]
OMIM: "Loose-jointedness" [OMIM:Loose-jointedness]
OMIM: "Loosejointedness" [OMIM:Loosejointedness]
OMIM: "Joint hypermobility (in some patients)" [OMIM:Joint hypermobility (in some patients)]
OMIM: "Joint hypermobility (large and small joints)" [OMIM:Joint hypermobility (large and small joints)]
OMIM: "Joint hypermobility (rare)" [OMIM:Joint hypermobility (rare)]
OMIM: "Joint laxity (elbow)" [OMIM:Joint laxity (elbow)]
OMIM: "Joint laxity (elbow, wrist, fingers)" [OMIM:Joint laxity (elbow, wrist, fingers)]
OMIM: "Joint laxity (except elbow)" [OMIM:Joint laxity (except elbow)]
OMIM: "Joint laxity (fingers and wrist)" [OMIM:Joint laxity (fingers and wrist)]
OMIM: "Joint laxity (hands and feet)" [OMIM:Joint laxity (hands and feet)]
OMIM: "Joint laxity (hip, knee, shoulder, wrist, fingers)" [OMIM:Joint laxity (hip, knee, shoulder, wrist, fingers)]
UMLS:C0086437 "Hypermobility, Joint" [Orphanet:46360]
Is a (Direct Parents):
Orphanet Abnormal cartilage morphology
MedDRA Joint related disorders NEC
HPO         Joint hypermobility
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal joint morphology(HPO:0001367)
                Abnormality of joint mobility(HPO:0011729)
                   Joint hypermobility(HPO:0001382)
                      Joint laxity(HPO:0001388)
MedDRA:
Musculoskeletal and connective tissue disorders(MedDRA:10028395)
    Joint disorders(MedDRA:10023213)
       Joint related disorders NEC(MedDRA:10027685)
          Joint laxity(HPO:0001388)
Database Frequency: 117 / 7739
Resource:

All diseases associated with this symptom:

15q24 microdeletion syndrome (Orphanet:94065)
48,XXYY syndrome (Orphanet:10)
ACHARD SYNDROME (OMIM:100700)
Acromesomelic dysplasia, Maroteaux type (Orphanet:40)
Aneurysm - osteoarthritis syndrome (Orphanet:284984)
Arterial tortuosity syndrome (Orphanet:3342)
Aspartylglucosaminuria (Orphanet:93)
Atkin-Flaitz syndrome (Orphanet:1193)
Autosomal dominant Larsen syndrome (Orphanet:503)
Autosomal recessive cutis laxa type 1 (Orphanet:90349)
BRITTLE CORNEA SYNDROME 1 (OMIM:229200)
BRUCK SYNDROME 1 (OMIM:259450)
Blepharophimosis-intellectual deficit syndrome, Ohdo type (Orphanet:2728)
Brittle cornea syndrome (Orphanet:90354)
Bruck syndrome (Orphanet:2771)
CATEL-MANZKE SYNDROME (OMIM:616145)
CLARK-BARAITSER SYNDROME (OMIM:300602)
COFFIN-SIRIS SYNDROME (OMIM:135900)
CUTIS LAXA, AUTOSOMAL RECESSIVE, TYPE IA (OMIM:219100)
Cabezas syndrome (Orphanet:85293)
Cardiodysrhythmic potassium-sensitive periodic paralysis (Orphanet:37553)
Catel-Manzke syndrome (Orphanet:1388)
Cerebro-facio-articular syndrome (Orphanet:314679)
Cerebro-facio-thoracic dysplasia (Orphanet:1394)
Coffin-Siris syndrome (Orphanet:1465)
Congenital muscular dystrophy, Ullrich type (Orphanet:75840)
Costello syndrome (Orphanet:3071)
Cranioectodermal dysplasia (Orphanet:1515)
Cranioectodermal dysplasia 1 (OMIM:218330)
Cranioectodermal dysplasia 2 (OMIM:613610)
Cranioectodermal dysplasia 3 (OMIM:614099)
Craniofrontonasal dysplasia (Orphanet:1520)
Craniolenticulosutural dysplasia (Orphanet:50814)
Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies (Orphanet:221145)
DESBUQUOIS DYSPLASIA 1 (OMIM:251450)
DESBUQUOIS DYSPLASIA 2 (OMIM:615777)
Desbuquois syndrome (Orphanet:1425)
Dislocation of the hip - dysmorphism (Orphanet:2412)
Down syndrome (Orphanet:870)
EHLERS-DANLOS SYNDROME, AUTOSOMAL DOMINANT, TYPE UNSPECIFIED (OMIM:130090)
EHLERS-DANLOS SYNDROME, BEASLEY-COHEN TYPE (OMIM:608763)
EHLERS-DANLOS SYNDROME, PROGEROID TYPE, 1 (OMIM:130070)
EPIPHYSEAL DYSPLASIA, BAUMANN TYPE (OMIM:610797)
Ear-patella-short stature syndrome (Orphanet:2554)
Ehlers-Danlos syndrome type 11 (Orphanet:2295)
Ehlers-Danlos syndrome type 2 (Orphanet:90318)
Ehlers-Danlos syndrome, arthrochalasic type (Orphanet:1899)
Ehlers-Danlos syndrome, cardiac valvular type (Orphanet:230851)
Ehlers-Danlos syndrome, dermatosparaxis type (Orphanet:1901)
Ehlers-Danlos syndrome, fibronectinemic type (Orphanet:75501)
Ehlers-Danlos syndrome, hypermobility type (Orphanet:285)
Ehlers-Danlos syndrome, kyphoscoliotic type (Orphanet:1900)
Ehlers-Danlos syndrome, musculocontractural type (Orphanet:2953)
Ehlers-Danlos syndrome, periodontitis type (Orphanet:75392)
Ehlers-Danlos syndrome, progeroid type (Orphanet:75496)
Ehlers-Danlos syndrome, spondylocheirodysplastic type (Orphanet:157965)
Floating-Harbor syndrome (Orphanet:2044)
Focal dermal hypoplasia (Orphanet:2092)
Fragile X syndrome (Orphanet:908)
HAJDU-CHENEY SYNDROME (OMIM:102500)
HELSMOORTEL-VAN DER AA SYNDROME (OMIM:615873)
HEMANGIOMATOSIS, CUTANEOUS, WITH ASSOCIATED FEATURES (OMIM:234800)
Hydrocephaly - tall stature - joint laxity (Orphanet:2181)
Hypospadias - intellectual deficit, Goldblatt type (Orphanet:2261)
Johanson-Blizzard syndrome (Orphanet:2315)
Joubert syndrome 18 (OMIM:614815)
Kaler-Garrity-Stern syndrome (Orphanet:2324)
LOEYS-DIETZ SYNDROME 1 (OMIM:609192)
LOEYS-DIETZ SYNDROME 2 (OMIM:610168)
LOEYS-DIETZ SYNDROME, TYPE 2A (OMIM:608967)
LUJAN-FRYNS SYNDROME (OMIM:309520)
Larsen-like osseous dysplasia - short stature (Orphanet:2370)
Larsen-like syndrome, B3GAT3 type (Orphanet:284139)
Loeys-Dietz syndrome type 1 (Orphanet:60030)
MACROEPIPHYSEAL DYSPLASIA WITH OSTEOPOROSIS, WRINKLED SKIN, AND AGEDAPPEARANCE (OMIM:248010)
MEIER-GORLIN SYNDROME 1 (OMIM:224690)
METAPHYSEAL DYSPLASIA WITHOUT HYPOTRICHOSIS (OMIM:250460)
MICROCEPHALY, SHORT STATURE, AND IMPAIRED GLUCOSE METABOLISM (OMIM:616033)
MUSCULAR DYSTROPHY, CONGENITAL, MEROSIN-POSITIVE (OMIM:609456)
Marfan syndrome type 2 (Orphanet:284973)
Megalencephaly-capillary malformation-polymicrogyria syndrome (Orphanet:60040)
Menkes disease (Orphanet:565)
Metaphyseal dysostosis - intellectual deficit - conductive deafness (Orphanet:2502)
Microcephaly - glomerulonephritis - marfanoid habitus (Orphanet:2172)
Monosomy 18q (Orphanet:1600)
Mucopolysaccharidosis type 4A (Orphanet:309297)
Mucopolysaccharidosis type 4B (Orphanet:309310)
Multiple endocrine neoplasia type 2B (Orphanet:247709)
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia (Orphanet:363972)
OSTEOGENESIS IMPERFECTA, TYPE VIII (OMIM:610915)
OSTEOGENESIS IMPERFECTA, TYPE X (OMIM:613848)
OSTEOGENESIS IMPERFECTA, TYPE XI (OMIM:610968)
OSTEOGENESIS IMPERFECTA, TYPE XIII (OMIM:614856)
Occipital horn syndrome (Orphanet:198)
Perinatal lethal hypophosphatasia (Orphanet:247623)
Peters-plus syndrome (Orphanet:709)
Pseudoachondroplasia (Orphanet:750)
Renal coloboma syndrome (Orphanet:1475)
Renal cysts and diabetes syndrome (Orphanet:93111)
Rubinstein-Taybi syndrome due to CREBBP mutations (Orphanet:353277)
SHORT syndrome (Orphanet:3163)
SOTOS SYNDROME 1 (OMIM:117550)
Shprintzen-Goldberg syndrome (Orphanet:2462)
Sotos syndrome (Orphanet:821)
Spondyloepimetaphyseal dysplasia with joint laxity (Orphanet:93359)
Spondyloepimetaphyseal dysplasia with multiple dislocations (Orphanet:93360)
Spondyloepimetaphyseal dysplasia, Shohat type (Orphanet:93352)
Spondyloepimetaphyseal dysplasia, aggrecan type (Orphanet:171866)
Spondyloepiphyseal dysplasia, Reardon type (Orphanet:163662)
Syndromic microphthalmia type 5 (Orphanet:178364)
TMEM165-CDG (Orphanet:314667)
VAN MALDERGEM SYNDROME 1 (OMIM:601390)
VAN MALDERGEM SYNDROME 2 (OMIM:615546)
WARBURG MICRO SYNDROME 1 (OMIM:600118)
Williams syndrome (Orphanet:904)
Wilson disease (Orphanet:905)
X-linked Ehlers-Danlos syndrome (Orphanet:75497)