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Chromosome
(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
RLF2 Chromatin assembly complex, subunit p90 
Entry:YPR018w
Alias:CAC1; LRS8; PAX14; YP9531.12
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (13.5 %) ;  |  Homologs in   Hemiascomycota (83.5 %);  Basidiomycota (21.2 %);  Fungi (83.5 %);  Eukaryota (83.5 %);  Plants (15.9 %);  Mammalia (12.1 %);  Human (15.7 %);  Bacteria (19.7 %);  All except yeast (83.5 %)
  • similarity to human chromatin assembly factor I p150 chain
Functional Classification:
  • CELL CYCLE AND DNA PROCESSING
    ..DNA processing
    ....DNA synthesis and replication | 138 Entries | Evi
  • CELL CYCLE AND DNA PROCESSING
    ..DNA processing
    ....DNA restriction or modification
    ......DNA conformation modification (e.g. chromatin) | 187 Entries | Evi | PUBMED
  • PROTEIN FATE (folding, modification, destination)
    ..assembly of protein complexes | 199 Entries | Evi
  • CELL CYCLE AND DNA PROCESSING
    ..cell cycle
    ....nuclear and chromosomal cycle
    ......centromere/kinetochore complex maturation | 13 Entries | Evi | PUBMED
Pathway:
  • DNA replication
Localization:  RLF2 localization details
  • nucleus
  • nucleus
    ..chromosome structure
  • nucleus
    ..centromere/kinetochore
Remarks:
  • CAC1p sequence was determined by amino acid sequencing
  • possible coiled-coil region
Phenotypes:  Disruption: RLF2 details
  • viable
___
  • rlf2 disruption mutant is UV sensitive
  • increased UV-sensitivity, without significantly increased gamma-ray-sensitivity
  • rlf2 mutant shows pertubed telomeric chromatin and alterd Rap1p localization
___
  • Nucleic acid metabolism defects
    ..DNA repair mutants
    ....UV light sensitivity | 41 Entries
Click for larger Map
Physical Features
Coordinates:594473 - 596293 (W)
Length:1821 nt
Contig:chrXVI
Exon Coordinates:594473 - 596293
GC Content:38.5 %
Protein Length:606 aa
Isoelectric Point:6.38
Molecular Weight:70210.2 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z49919
PIR: S57552
UniProtKB: Q12495
NCBI: NP_015343
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
    • To submit new information about this entry, please write to

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