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Chromosome
(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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MPact protein interaction

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WUBLAST DNA/Protein

About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
PDR12 `Full-size` ABC transporter of the plasma membrane acting as a weak organic acids extrusion pump 
Entry:YPL058c
Alias:LPE14
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (44.8 %) ;  |  Homologs in   Hemiascomycota (84.4 %);  Basidiomycota (40.1 %);  Fungi (84.4 %);  Eukaryota (84.4 %);  Plants (25.8 %);  Mammalia (11.7 %);  Human (13.3 %);  Bacteria (11 %);  All except yeast (84.4 %)
  • strong similarity to Snq2p, YNR070w and similarity to Pdr5p, S.pombe hba2 and bfr1+ protein
Functional Classification:
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....drug/toxin transport | 39 Entries | Evi | PUBMED
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport facilities
    ....transport ATPases | 54 Entries | Evi | PUBMED
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transport facilities
    ....ABC transporters | 28 Entries | Evi
  • PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
    ..nucleotide/nucleoside/nucleobase binding
    ....ATP binding | 191 Entries | Evi | PUBMED
  • CELLULAR TRANSPORT, TRANSPORT FACILITIES AND TRANSPORT ROUTES
    ..transported compounds (substrates)
    ....C-compound and carbohydrate transport | 63 Entries | Evi | PUBMED
EC Number:
  • 3.6.3.44: Hydrolases
    ..Acting on Acid Anhydrides
    ....Acting on acid anhydrides; catalysing transmembrane movement of substances
    ......xenobiotic-transporting ATPase | 5 Entries | Evi | PUBMED
TC Class:
  • The Driven Transporters
    ..The P-P Bond Hydrolysis - Driven Transporters
    ....The ATP Binding Cassette (ABC) Superfamily
    ......The Pleiotropic Drug Resistance (PDR) Subfamily | 9 Entries | Evi | PUBMED
InterPro:
Localization:  PDR12 localization details
  • cell periphery
  • integral membrane / endomembranes (not assigned to a specific membrane)
Phenotypes:  Disruption: PDR12 details
  • viable
Click for larger Map
Physical Features
Coordinates:450374 - 445839 (C)
Length:4536 nt
Contig:chrXVI
Exon Coordinates:450374 - 445839
GC Content:39.1 %
Protein Length:1511 aa
Isoelectric Point:6.4
Molecular Weight:171066 Da
Transmembrane Domains:Begin - End / Length (aa)
595 - 617 / 23
624 - 646 / 23
656 - 678 / 23
764 - 786 / 23
1177 - 1199 / 23
1211 - 1233 / 23
1248 - 1269 / 22
1290 - 1312 / 23
1322 - 1340 / 19
1353 - 1372 / 20
1447 - 1466 / 20
11 TM- Domains
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: U39205
PIR: S60932
UniProtKB: Q02785
NCBI: NP_015267
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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