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(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
MBF1 Multiprotein bridging factor mediates GCN4-dependent transcriptional activation 
Entry:YOR298c-a
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (9.3 %) ;  |  Homologs in   Hemiascomycota (99.3 %);  Basidiomycota (49.7 %);  Fungi (99.3 %);  Eukaryota (99.3 %);  Plants (37.7 %);  Mammalia (45.7 %);  Human (44.4 %);  Bacteria (16.7 %);  All except yeast (99.3 %)
  • similarity to multiprotein bridging factor 1 of Bombyx mori <
  • similarity to D. discoideum vegetative specific protein H7
Functional Classification:
  • REGULATION OF METABOLISM AND PROTEIN FUNCTION
    ..regulation of protein activity
    ....regulator of transcription factor | 37 Entries | Evi | PUBMED
InterPro:
Localization:  MBF1 localization details
  • cytoplasm
  • nucleus
  • mitochondria
Remarks:
  • identified by SAGE expression analysis | PUBMED
  • by homology to hemiascomycetous yeasts this orf can be extended for 92 aa N-terminal | PUBMED
  • Due to a insertion of GC after a G at position 877622 verified by genomic PCR YOR298c-a/MBF1 coordinates change from 877403 - 877227 to 877682 - 877227, 454nt (151aa). | Evi | PUBMED
    Phenotypes:  Disruption: MBF1 details
    • viable
    ___
    • null mutant shows reduced transcription of HIS3
    Click for larger Map
    Physical Features
    Coordinates:877684 - 877229 (C)
    Length:456 nt
    Contig:chrXV
    Exon Coordinates:877684 - 877229
    GC Content:46.3 %
    Protein Length:151 aa
    Isoelectric Point:10.61
    Molecular Weight:16403.7 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z75206
    PIR: S72394
    UniProtKB: O14467
    Additional Links:
    LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer
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