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(chrI - chrXVI,chrMito,2-micron)

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  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
GRE2 Methylglyoxal reductase (NADPH-dependent) 
Entry:YOL151w
Alias:AOA342; O0446
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (59 %) ;  |  Homologs in   Hemiascomycota (93.6 %);  Basidiomycota (38.2 %);  Fungi (93.6 %);  Eukaryota (93.6 %);  Plants (33.1 %);  Mammalia (22.5 %);  Human (22.5 %);  Bacteria (35.1 %);  All except yeast (93.6 %)

  • strong similarity to YDR541c and YGL039w, similarity to plant dihydroflavonol-4-reductases
Functional Classification:
  • CELL RESCUE, DEFENSE AND VIRULENCE
    ..stress response
    ....osmotic and salt stress response | 59 Entries | Evi | PUBMED
  • CELL RESCUE, DEFENSE AND VIRULENCE
    ..detoxification
    ....detoxification by modification | 8 Entries | Evi | PUBMED
  • METABOLISM
    ..metabolism of vitamins, cofactors, and prosthetic groups
    ....biosynthesis of vitamins, cofactors, and prosthetic groups | 110 Entries | Evi
EC Number:
  • 1.1.1.78: Oxidoreductases
    ..Acting on the CH-OH group of donors
    ....With NAD+ or NADP+ as acceptor
    ......methylglyoxal reductase (NADH-dependent) | 1 Entry | Evi | PUBMED
InterPro:
Localization:  GRE2 localization details
  • cytoplasm
  • nucleus
Remarks:
  • induced by osmotic stress
  • methylglyoxal reductase (NADPH-dependent) | Evi | PUBMED
    Phenotypes:  Disruption: GRE2 details
    • viable
    Click for larger Map
    Physical Features
    Coordinates:43693 - 44721 (W)
    Length:1029 nt
    Contig:chrXV
    Exon Coordinates:43693 - 44721
    GC Content:41.6 %
    Protein Length:342 aa
    Isoelectric Point:5.78
    Molecular Weight:38169.6 Da
    Retrieve Sequence: DNA /Protein
    Literature | References
    CYGD curated Lit.:PubMed
    PubMed:Search abstracts
    PubMed Central:Search full-text articles
    Sequence References:
    EMBL: Z74893
    EMBL: Z48239
    PIR: S60386
    UniProtKB: Q12068
    NCBI: NP_014490
    Additional Links:
    LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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