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(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
RTG1 Basic helix-loop-helix transcription factor that regulates CIT2 gene expression 
Entry:YOL067c
Alias:O1165
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (6.9 %) ;  |  Homologs in   Hemiascomycota (98.3 %);  Basidiomycota (17.2 %);  Fungi (98.3 %);  Eukaryota (98.3 %);  Plants (13 %);  Mammalia (11.9 %);  Human (10.8 %);  Bacteria (21.5 %);  All except yeast (98.3 %)

  • weak similarity to N.crassa nuc1 and Rtg3p
Functional Classification:
  • METABOLISM
    ..C-compound and carbohydrate metabolism
    ....regulation of C-compound and carbohydrate metabolism | 127 Entries | Evi
  • TRANSCRIPTION
    ..RNA synthesis
    ....mRNA synthesis
    ......transcriptional control | 495 Entries | Evi
  • PROTEIN FATE (folding, modification, destination)
    ..protein targeting, sorting and translocation | 280 Entries | Evi | PUBMED
  • REGULATION OF METABOLISM AND PROTEIN FUNCTION
    ..regulation of protein activity
    ....regulator of transcription factor | 37 Entries | Evi | PUBMED
  • TRANSCRIPTION
    ..RNA synthesis
    ....mRNA synthesis
    ......general transcription activities
    ........transcription initiation | 46 Entries | Evi | PUBMED
InterPro:
Localization:  RTG1 localization details
  • cytoplasm
  • nucleus
Remarks:
  • level of protein does not differ between rho0 and rho+ cells
  • helix-loop-helix domain is required for transactivation
Phenotypes:  Disruption: RTG1 details
  • viable
___
  • null mutants are auxotrophic for glutamate and cannot utilize acetate as carbon source
___
  • Auxotrophies, carbon and nitrogen utilization defects
    ..Nitrogen utilization
    ....Glutamate auxotrophy | 4 Entries
Click for larger Map
Physical Features
Coordinates:202518 - 201985 (C)
Length:534 nt
Contig:chrXV
Exon Coordinates:202518 - 201985
GC Content:49.8 %
Protein Length:177 aa
Isoelectric Point:5.89
Molecular Weight:19016.1 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z74809
EMBL: M97690
PIR: S66760
UniProtKB: P32607
NCBI: NP_014574
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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