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(chrI - chrXVI,chrMito,2-micron)

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  VIII  IX  X  XI  XII  XIII
  XIV  XV  XVI  Mito
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About CYGD


MIPS Fungal Genomes
mips home MIPS-FUNGI-ADM      FTP
FUS2 Protein required for cell fusion during mating 
Entry:YMR232w
Alias:YM9959.14
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW
Similarity:
Paralogs (19.6 %) ;  |  Homologs in   Hemiascomycota (89.5 %);  Basidiomycota (11.7 %);  Fungi (89.5 %);  Eukaryota (89.5 %);  Plants (14.7 %);  Mammalia (17.1 %);  Human (17.1 %);  Bacteria (19 %);  All except yeast (89.5 %)
    Functional Classification:
    • INTERACTION WITH THE ENVIRONMENT
      ..cellular sensing and response to external stimulus
      ....chemoperception and response
      ......pheromone response, mating-type determination, sex-specific proteins | 189 Entries | Evi
    Pathway:
    • | default mating pathway requires Axl1p, Fus1p, Fus2p, Fus3p, Pea2p, Rvs161p, Bni1p and Spa2p
    • | these proteins are also required for efficient cell fusion during chemotropic mating
    InterPro:
    Localization:  FUS2 localization details
    • cytoplasm
    • mitochondria
    Remarks:
    • fusion is only moderately impaired when 1 or 2 of the 4 FUS1/FUS2 genes of the diploid parents is mutated
    • fusion is severely impaired when 3 or 4 of the 4 FUS1/FUS2 genes of the diploid parents are mutated
      Phenotypes:  Disruption: FUS2 details
      • viable
      Overexpression:
      • suppresses spa2p default mating defect
      Click for larger Map
      Physical Features
      Coordinates:736925 - 738958 (W)
      Length:2034 nt
      Contig:chrXIII
      Exon Coordinates:736925 - 738958
      GC Content:34 %
      Protein Length:677 aa
      Isoelectric Point:8.98
      Molecular Weight:79037.6 Da
      Retrieve Sequence: DNA /Protein
      Literature | References
      CYGD curated Lit.:PubMed
      PubMed:Search abstracts
      PubMed Central:Search full-text articles
      Sequence References:
      EMBL: Z49939
      PIR: S57599
      UniProtKB: Q05670
      NCBI: NP_013959
      Additional Links:
      LinkOut:
    • SGD - Saccharomyces Genome Database
    • YGOB - Yeast Gene Order Browser
    • yMGV - yeast Microarray Global Viewer
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