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(chrI - chrXVI,chrMito,2-micron)

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About CYGD


MIPS Fungal Genomes

mips home MIPS-FUNGI-ADM      FTP
REX2 Putative 3`-5` exonuclease 
Entry:YLR059c
Alias:L2159; YNT20
Classification:known protein | 5422 Entries | Evi | PUBMED
Feature Type:CDS
Features
   Blast-Simap    DNA VIEW    PROTEIN VIEW

Similarity:
Paralogs (6.1 %) ;  |  Homologs in   Hemiascomycota (94.1 %);  Basidiomycota (34.6 %);  Fungi (94.1 %);  Eukaryota (94.1 %);  Plants (31.3 %);  Mammalia (31.2 %);  Human (29.8 %);  Bacteria (31.6 %);  All except yeast (94.1 %)

  • similarity to hypothetical proteins HI1715 (H.influenzae) and o204a (E.coli)
Functional Classification:
  • METABOLISM
    ..nucleotide/nucleoside/nucleobase metabolism
    ....polynucleotide degradation | 86 Entries | Evi | PUBMED
InterPro:
Localization:  REX2 localization details
  • nucleus
  • mitochondria
  • mitochondria
    ..mitochondrial matrix
 TargetP: Mitochondrion  (RC = 1)
 Mitop2:  Mitochondrial probability - 98  %
Remarks:
  • YNT20 plays a role in the yme1-mediated mitochondrial DNA escape pathway | PUBMED
  • N-terminal mitochondrial targeting sequence, typical for two-step-cleavage | PUBMED
Phenotypes:  Disruption: REX2 details
  • viable
___
  • cold-sensitive respiratory growth defect | PUBMED
Click for larger Map
Physical Features
Coordinates:260548 - 259739 (C)
Length:810 nt
Contig:chrXII
Exon Coordinates:260548 - 259739
GC Content:48.1 %
Protein Length:269 aa
Isoelectric Point:6.56
Molecular Weight:30870.4 Da
Retrieve Sequence: DNA /Protein
Literature | References
CYGD curated Lit.:PubMed
PubMed:Search abstracts
PubMed Central:Search full-text articles
Sequence References:
EMBL: Z73231
EMBL: X94607
EMBL: L47977
PIR: S61633
UniProtKB: P54964
NCBI: NP_013160
Additional Links:
LinkOut:
  • SGD - Saccharomyces Genome Database
  • YGOB - Yeast Gene Order Browser
  • yMGV - yeast Microarray Global Viewer

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