|
|
| Search ORF/Gene/Description |
|
|
|
Chromosome
(chrI - chrXVI,chrMito,2-micron) |
|
|
|
|
|
|
| |
| |
|
|
| Entry: | YLL039c | | Alias: | L0904; SCD2 | | Classification: | known protein | 5422 Entries | Evi
|
PUBMED
| | Feature Type: | CDS | | Features |  |
Blast-Simap
DNA VIEW
PROTEIN VIEW
| | Similarity: |
nearly identical to other ubiquitin precursors | | Functional Classification: | - CELL TYPE DIFFERENTIATION
..fungal/microorganismic cell type differentiation
....fungal and other eukaryotic cell type differentiation
......development of asco- basidio- or zygospore
| 167 Entries | Evi
|
PUBMED
- PROTEIN FATE (folding, modification, destination)
..protein modification
....modification by ubiquitination, deubiquitination
| 79 Entries | Evi
|
PUBMED
- PROTEIN FATE (folding, modification, destination)
..assembly of protein complexes
| 199 Entries | Evi
- PROTEIN FATE (folding, modification, destination)
..protein/peptide degradation
....cytoplasmic and nuclear protein degradation
| 188 Entries | Evi
- PROTEIN WITH BINDING FUNCTION OR COFACTOR REQUIREMENT (structural or catalytic)
..protein binding
| 392 Entries | Evi
|
PUBMED
| |
InterPro:
| | | Localization: | UBI4 localization details | | Remarks: | induced during sporulationinduced by starvation, cadmium, DNA-damaging agents, and heat shockcatabolite derepession is dependent on HAP2/3/4 binding site at -542 and on Hap1pdisruption of the PHO85 gene inappropriately triggers the derepression of stress response genes, HSP12 and UBI4 |
PUBMED
polyubiquitin;5 monomeres (76 aa) + N mature protein cleaved from polyubiquitin (ubi4) or from fusion genes with ribosomal proteins (s37, cep52a, and cep52b)UBI4 gene codes for a polyprotein containing 5 exact head to tail repeats of ubiquitin, there is a final amino-acid (asn) after the last repeat | | Phenotypes: | Disruption: UBI4 details___
mutant cells lose viability when grown to stationary phase in glucose-rich medium or when starved for nitrogenubi4 mutants are hypersensitive to growth at 38.5Cubi4 mutants are more sensitive to amino acid analogs and to starvation for nitrogen and carbon than wildtype cellsubi4 mutants are unable to sporulateexpression of a Lys-63 mutant ubiquitin in ubi4-deleted cells affects stress resistancemutation of leucine at position 8 to alanine is lethalmutant cells are sensitive to H2O2 inactivation ___
Conditional phenotypes
..Heat-sensitivity (ts) | 313 Entries Mating and sporulation defects
..other mating and sporulation defects | 54 Entries Stress response defects
..Starvation sensitivity | 26 Entries Stress response defects
..Oxidizing agents
....H2O2
......H2O2 sensitivity | 18 Entries Stress response defects
..other stress response defects | 9 Entries Sensitivity to aminoacid analogs and other drugs
..other aminoacid analogs and other drugs | 51 Entries | | Overexpression: | overexpression can suppress cdc34-2 mutation |
| |
| Additional Links: |
To submit new information about this entry, please write to  |
|
|
|
