| Entry: | YLL016w |
| Alias: | L1305; L1309; SCD25; YLL017w |
| Feature Type: | pseudogene |
| Features |
| Similarity: |
similarity to S.kluyveri CDC25, Cdc25p, S.pombe ste6 and mammalian cdc25 proteinssimilarity to other guanine-nucleotide releasing factors of the CDC25 family |
| Functional Classification: | - INTERACTION WITH THE ENVIRONMENT
..cellular sensing and response to external stimulus
....perception of nutrients and nutritional adaptation
| 33 Entries | Evi
- METABOLISM
..C-compound and carbohydrate metabolism
....regulation of C-compound and carbohydrate metabolism
| 127 Entries | Evi
- CELL CYCLE AND DNA PROCESSING
..cell cycle
....mitotic cell cycle and cell cycle control
| 447 Entries | Evi
- REGULATION OF METABOLISM AND PROTEIN FUNCTION
..regulation of protein activity
....regulator of G-protein signalling
| 15 Entries | Evi
|
|
InterPro:
| |
| Localization: | SDC25 localization details |
| Remarks: | L1305 and L1309 can be joined to one genen the S288C strain, there is a stop codon between YLL017W and YLL016W, the ORFs that comprise SDC25, while in other strains the stop codon is absent and the ORFs are merged into one longer ORF contains a copy of the SH3 domain |
PUBMED
contains a cyclin destruction box and is unstable |
PUBMED
C-terminal part is 47% identical to Cdc25p, similartity of N-terminus is lower |
PUBMED
C-terminal part can enhance GDP/GTP exchange on Ras2p |
PUBMED
|
| Phenotypes: | Disruption: SDC25 details___
null mutant has no phenotype |
PUBMED
|
| Overexpression: | overexpression replaces Cdc25p functionally |
PUBMED
|
| Suppression: | C-terminal part suppresses cdc25 |
PUBMED
complete SDC25 gene does not suppress cdc25 |
PUBMED
|
